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Anan'ev VN Anan'eva OV Kichikulova TP Manukhin BN 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2003,89(1):90-98
Changes in major paraments of alpha 1- and beta-adrenergic responses (EC50 and Pm) were studied in the intestine arterial blood vessels of rabbits adapted to cold for 1-30 days (daily cold exposures for 6 hours at -10 degrees C). It was shown that responses to phenylephrine, noradrenaline, adrenaline (alpha 1-agonists), isopropylnoradrenaline (beta-agonist) corresponded to the equation p = (Pm.An)/(EC50n + An) with n = 1 and n = 2, respectively. Adaptation to cold induced radically different changes in the major parameters of alpha- and beta-adrenergic responses. In the alpha-adrenergic responses, the parameters EC50 and Pm changed reciprocally. In the beta-adrenergic response, only Pm value changed while EC50 did not differ from the control over the entire period of adaptation to cold. The pronounced differences from the control gradually decreased within 1-30 days of adaptation. 相似文献
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Anan'eva TV Dvoretskiĭ AI 《Radiatsionnaia biologiia, radioecologiia / Rossi?skaia akademiia nauk》2000,40(3):266-271
It had been found that both the single prolonged irradiation and chronic (fractionated) one with doses of 25 and 50 cGy (1.75 mGy/min) caused essential modification of the biphase modulative effects of acetylcholine and gamma-aminobutyric acid upon K+ level in rat brain cortex slices to be compared to the acute lethal irradiation influence. The results of model experiments showed saturated fatty acids to be significant for the changes in regulative functions of nerve cell membranes after exposure to low dose-rate radiation. 相似文献
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Anan'eva TV Likholat EA Dvoretskiĭ AI 《Radiatsionnaia biologiia, radioecologiia / Rossi?skaia akademiia nauk》2000,40(4):410-415
It was shown that chronic 0.25 Gy irradiation of rats (0.01 Gy/day) at background of heavy metal penetration (Cu2+, 20 mg/l or Co2+, 5 mg/l) with drinking water had caused significant accumulation of the free-radical products proportional to exhausting antioxidant and oxidizing-reduction potential in various organs and tissues. Radiation was shown to be primary harmful factor for the brain, spleen, lungs, and blood plasma, whereas the liver and heart muscle were affected with chemicals at first. Under prolonged unfavourable influence the biochemical changes observed were sustainable and progressing that satisfied to transformation of protective-adaptive reactions into prepathology stage. 相似文献
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Tundra, chernozem (virgin and arable), sod-podzolic (coniferous forest, meadow, and arable), and grey forest (larch forest) soils were used to separate the contributions of fungi and bacteria to substrate-induced respiration (SIR) with the help of antibiotics. For soils with a high content of organic matter (tundra and chernozem: 12 and 8%, respectively), the procedure of selective inhibition of SIR has been optimized. The optimized procedure includes the application of high concentrations of streptomycin (50-120 mg/g of soil) and cycloheximide (50-80 mg/g of soil) and decreasing the weight of the analyzed soil sample. Soils under study have shown the predominant contribution of fungi (63-82%) to the total SIR. The fungal-bacterial ratio in the soils of natural ecosystems (0-5 cm, without litter) was 4.32, 2.19, 1.5, and 1.5 for tundra soil, virgin chernozem, coniferous (sod-podzolic soil), and larch (grey forest soil) forests, respectively. The lower layers of sod-podzolic (5-10 cm) and grey forest (48-58 cm) soils showed a decrease in the fungal and increase in the bacterial component in the total SIR. 相似文献
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I N Manzeniuk M S Vorob'eva N M Nikitiuk E A Arumova L P Anan'eva S G Baranova T G Viatkina A V Masiago A A Kozarenko Iu A Andre?chuk 《Antibiotiki i khimioterapii͡a》2004,49(8-9):25-28
One foreign and two Russian recombinant enzyme immunoassay test-systems were comparatively investigated under conditions of an encoded experiment. Sensitivity in the experiment with the Russian test-systems Borreliosis-ELISA-IgG and Lyme Best was 63.8 and 68.8% respectively. As for the test-system Borrelia IgG Recombinant, it was 47.5%. All the test-systems were highly specific (94.4 to 99.5%). The test-systems Lyme Best and Borrelia IgG Recombinant revealed partial cross reactions with sera from patients with systemic lupus erythematosus and leptospirosis. 相似文献
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S K Anan'eva 《Biulleten' eksperimental'no? biologii i meditsiny》1975,80(11):32-34
A study was made of the dynamics of the lysozyme activity of the serum in dogs which sustained clinical death on the background of a 2-hour hypovolemic hypotension due to blood loss. There was revealed a progressive increase in the lysozyme activity of the serum during the hypotension and during the first 30 minutes of the postreanimation period. Lysozyme activity of the serum was increased in the course of 4 days after the revival. The significance of the lysozyme activity of the serum as an index of hypoxic injury of the internal organs in terminal conditions is discussed. 相似文献