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1.
P. Bourke D. Ziuzina L. Han P.J. Cullen B.F. Gilmore 《Journal of applied microbiology》2017,123(2):308-324
There is a diverse range of microbiological challenges facing the food, healthcare and clinical sectors. The increasing and pervasive resistance to broad‐spectrum antibiotics and health‐related concerns with many biocidal agents drives research for novel and complementary antimicrobial approaches. Biofilms display increased mechanical and antimicrobial stability and are the subject of extensive research. Cold plasmas (CP) have rapidly evolved as a technology for microbial decontamination, wound healing and cancer treatment, owing to the chemical and bio‐active radicals generated known collectively as reactive oxygen and nitrogen species. This review outlines the basics of CP technology and discusses the interactions with a range of microbiological targets. Advances in mechanistic insights are presented and applications to food and clinical issues are discussed. The possibility of tailoring CP to control specific microbiological challenges is apparent. This review focuses on microbiological issues in relation to food‐ and healthcare‐associated human infections, the role of CP in their elimination and the current status of plasma mechanisms of action. 相似文献
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《Developmental cell》2023,58(15):1383-1398.e6
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Hybrid crosses and the genetic basis of interspecific divergence in lifespan in Pristionchus nematodes 下载免费PDF全文
Characterizing the genetic basis of among‐species variation in lifespan is a major goal of evolutionary gerontology research, but the very feature that defines separate species – the inability to interbreed – makes achieving this goal impractical, if not impossible, for most taxa. Pristionchus nematodes provide an intriguing system for tackling this problem, as female lifespan varies among species that can be crossed to form viable (although infertile) hybrids. By conducting reciprocal crosses among three species – two dioecious (long‐lived Pristionchus exspectatus and short‐lived Pristionchus arcanus) and one androdioecious (short‐lived Pristionchus pacificus) – we found that female lifespan was long for all hybrids, consistent with the hypothesis that the relatively short lifespans seen for P. pacificus hermaphrodites and P. arcanus females are caused by independent, recessive alleles that are masked in hybrid genomes. Cross‐direction had a small effect on survivorship for crosses involving P. exspectatus, indicating that nuclear–mitochondrial interactions may also influence Pristionchus longevity. Our findings suggest that long lifespan in P. exspectatus reflects the realization of an ancestral potential for extended longevity in the P. pacificus species complex. This work demonstrates the utility of interspecific hybrids for ageing research and provides a foundation for future work on the genetic architecture of interspecific lifespan variation. 相似文献
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《Biological reviews of the Cambridge Philosophical Society》2018,93(2):1192-1202
Hydra is emerging as a model organism for studies of ageing in early metazoan animals, but reef corals offer an equally ancient evolutionary perspective as well as several advantages, not least being the hard exoskeleton which provides a rich fossil record as well as a record of growth and means of ageing of individual coral polyps. Reef corals are also widely regarded as potentially immortal at the level of the asexual lineage and are assumed not to undergo an intrinsic ageing process. However, putative molecular indicators of ageing have recently been detected in reef corals. While many of the large massive coral species attain considerable ages (>600 years) there are other much shorter‐lived species where older members of some populations show catastrophic mortality, compared to juveniles, under environmental stress. Other studies suggestive of ageing include those demonstrating decreased reproduction, increased susceptibility to oxidative stress and disease, reduced regeneration potential and declining growth rate in mature colonies. This review aims to promote interest and research in reef coral ageing, both as a useful model for the early evolution of ageing and as a factor in studies of ecological impacts on reef systems in light of the enhanced effects of environmental stress on ageing in other organisms. 相似文献
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Cheng Qi Ao 《Journal of Plant Biology》2008,51(2):116-121
Platycrater arguta Sieb. et Zucc. is a rare and endangered species endemic to East Asia. It produces two floral morphs viz. bisexual and male
flowers. For bisexual flowers, simultaneous cytokinesis in the microsporocyte meiosis leads to a tetrahedral tetrad. The mature
pollen grain is shed at 2-cell stage. The young anther wall is composed of epidermis, endothecium that develops fibrous thickenings
at maturity, 1–2 middle layers and tapetum. The tapetum with uninucleate to binucleate cells, disintegrates in situ (glandular
tapetum), yet in a small percentage of the anthers (about 37.6%), the tapetum does not disintegrate, causing complete male
sterility. The ovules are anatropous, unitegmic, tenuinucellar and the formation of the embryo sac follows the monosporic,
Polygonum type. Antipodal cells are lacking in the mature embryo sacs. Before fertilization, two polar nuclei fuse into a
secondary nucleus. The formation of microsporangial wall, microsporogenesis and male gametogenesis in male flowers are analogous
to those in the bisexual. Prezygotic embryological characters ofP. arguta were reported for the first time, revealing that its endangerment is correlated with the abortion of pollen of a part but
not to the female development that is normal. 相似文献
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LIU Bing-yun CHEN Bing 《现代生物医学进展》2008,(12)
作为社会交往中的重要因素,共情是指理解并体验他人的情感和知觉感受的能力。目前的研究认为共情依赖于直接的投射机制而非逻辑推理。即观察到他人的情绪状态会涉及一部分处理自我情感的大脑结构的激活,该过程同时还会受到社会认知因素的调节。由于理解和间接体验他人痛觉的能力是维系社会纽带必不可少的,目前研究者越来越多地通过对痛觉共情的研究来揭示关于共情的普遍的神经机制。此外共情的动物模型、镜像神经元系统与共情的产生以及共情的调节等方向也将是研究的重点。 相似文献
10.
A. V. Kireyko I. A. Veselova T. N. Shekhovtsova 《Russian Journal of Bioorganic Chemistry》2006,32(1):71-77
Peroxidase oxidation of o-dianisidine, 3,3′,5,5′-tetramethylbenzidine, and o-phenylenediamine in the presence of sodium dodecyl sulfate (SDS), an anionic surfactant, was spectrophotometrically studied. It was found that 0.1–100 mM SDS concentrations stabilize intermediates formed in the peroxidase oxidation of these substrates. The cause of the stabilization is an electrostatic interaction between positively charged intermediates and negatively charged surfactant. 相似文献