全文获取类型
收费全文 | 4575篇 |
免费 | 549篇 |
国内免费 | 661篇 |
出版年
2023年 | 142篇 |
2022年 | 94篇 |
2021年 | 188篇 |
2020年 | 239篇 |
2019年 | 278篇 |
2018年 | 208篇 |
2017年 | 228篇 |
2016年 | 213篇 |
2015年 | 224篇 |
2014年 | 283篇 |
2013年 | 396篇 |
2012年 | 223篇 |
2011年 | 245篇 |
2010年 | 196篇 |
2009年 | 183篇 |
2008年 | 217篇 |
2007年 | 254篇 |
2006年 | 202篇 |
2005年 | 203篇 |
2004年 | 159篇 |
2003年 | 153篇 |
2002年 | 142篇 |
2001年 | 128篇 |
2000年 | 118篇 |
1999年 | 115篇 |
1998年 | 73篇 |
1997年 | 75篇 |
1996年 | 86篇 |
1995年 | 53篇 |
1994年 | 59篇 |
1993年 | 43篇 |
1992年 | 59篇 |
1991年 | 43篇 |
1990年 | 29篇 |
1989年 | 32篇 |
1988年 | 23篇 |
1987年 | 18篇 |
1986年 | 14篇 |
1985年 | 22篇 |
1984年 | 18篇 |
1983年 | 20篇 |
1982年 | 17篇 |
1981年 | 18篇 |
1980年 | 13篇 |
1979年 | 9篇 |
1978年 | 9篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1975年 | 7篇 |
1973年 | 4篇 |
排序方式: 共有5785条查询结果,搜索用时 15 毫秒
1.
Kelsey R. Downum Lee A. Swain Lavina J. Faleiro 《Archives of insect biochemistry and physiology》1991,17(4):201-211
Plant phototoxins are broad-spectrum biocides which adversely affect an array of potential plant enemies, including among others disease-causing pathogens, nematodes, insect herbivores, and competing plant species. Thus far, plants which contain these broad-spectrum allelochemicals have been found to occur in open habitats (i.e., in full sunlight) where a defensive mechanism mediated by light would seem to operate most effectively. The levels of available light in shaded environments, although considerably lower than full sun (1–10% of full sun), are equivalent to the intensities of light used to kill phototoxin-treated insects in laboratory studies. This suggests that phototoxic reactions might mediate important organismal interactions in shaded environments as well. In this study, more than 230 Costa Rican rainforest plants were bioassayed for phototoxic metabolites in an effort to ascertain their prevalence among plants growing in moderate to extreme shade. Microbial bioassays, employing Bacillus cereus (a gram positive bacterium), Escherichia coli (a gram negative bacterium), and Saccharomyces cerevisiae (a yeast) were used to rapidly and sensitively indicate phototoxic action and potential for insecticidal action. Tissue extracts from 12 plant families tested positive for phototoxins. This is the first report of phototoxins occurring in eight of those families (Acanthaceae, Campanulaceae, Gesnariaceae, Loganiaceae, Malpigaceae, Phytolaccaceae, Piperaceae, and Sapotaceae). The presence of phototoxins in rainforest plants suggests that phototoxic plant allelochemicals may function as important defenses in low-light, as well as high-light, environments. 相似文献
2.
Eiiti Kasuya 《Population Ecology》1993,35(2):251-255
An index of intensity of sexual selection proposed by Nishida (1992: Res. Popul. Ecol. 34: 373–382) was examined. Two examples were presented to show that Nishida's index was not free from confounding effect of mortality schedule. Importance of removing the phylogenetic effects in comparative analyses was also discussed. 相似文献
3.
Habitat management under the auspices of conservation biological control is a widely used approach to foster conditions that ensure a diversity of predator species can persist spatially and temporally within agricultural landscapes in order to control their prey (pest) species. However, an emerging new factor, global climate change, has the potential to disrupt existing conservation biological control programs. Climate change may alter abiotic conditions such as temperature, precipitation, humidity and wind that in turn could alter the life-cycle timing of predator and prey species and the behavioral nature and strength of their interactions. Anticipating how climate change will affect predator and prey communities represents an important research challenge. We present a conceptual framework—the habitat domain concept—that is useful for understanding contingencies in the nature of predator diversity effects on prey based on predator and prey spatial movement in their habitat. We illustrate how this framework can be used to forecast whether biological control by predators will become more effective or become disrupted due to changing climate. We discuss how changes in predator–prey interactions are contingent on the tolerances of predators and prey species to changing abiotic conditions as determined by the degree of local adaptation and phenotypic plasticity exhibited by species populations. We conclude by discussing research approaches that are needed to help adjust conservation biological control management to deal with a climate future. 相似文献
4.
Potential natural vegetation and pre‐anthropic pollen records on the Azores Islands in a Macaronesian context 下载免费PDF全文
This paper discusses the concept of potential natural vegetation (PNV) in the light of the pollen records available to date for the Macaronesian biogeographical region, with emphasis on the Azores Islands. The classical debate on the convenience or not of the PNV concept has been recently revived in the Canary Islands, where pollen records of pre‐anthropic vegetation seemed to strongly disagree with the existing PNV reconstructions. Contrastingly, more recent PNV model outputs from the Azores Islands show outstanding parallelisms with pre‐anthropic pollen records, at least in qualitative terms. We suggest the development of more detailed quantitative studies to compare these methodologies as an opportunity for improving the performance of both. PNV modelling may benefit by incorporating empirical data on past vegetation useful for calibration and validation purposes, whereas palynology may improve past reconstructions by minimizing interpretative biases linked to differential pollen production, dispersal and preservation. 相似文献
5.
The past few years have seen significant advances in our understanding of eukaryotic genomes. In the field of parasitology, this is best exemplified by the application of genome mapping techniques to the study of genome structure and function in the protozoan parasite, Leishmania. Although much is known about the organism and the diseases it causes, molecular genetics has only recently begun to play a major part in elucidating some of the unusual characteristics of this interesting parasite. Mapping of the small (35 Mb) genome and determination of the functional role of genes by the application of in vitro homologous gene targeting techniques are revealing novel avenues for the development of prophylactic measures. 相似文献
6.
7.
8.
9.
Natural antibodies to interferon-gamma 总被引:3,自引:0,他引:3
Natural antibodies to interferon (IFN)-γ were detected in the serum of virus-infected patients and also, at a low titre, in
the serum of healthy subjects. The increased titre of antibodies to IFN-γ in the sera of virus-infected patients, and its
decrease with clinical resolution, indicate that these antibodies are related to viral infection and probably reflect IFN-γ
production as a result of antigenic stimulationin vivo. Natural antibodies to IFN-γ were affinity purified and studied for their capability to interferein vitro with the multiple activities of the lymphokine. Data obtained show that these human anti-IFN-γ antibodies have no inhibitory
effect on the antiviral and antiproliferative activity of IFN-γ and do not interfere with the binding of the lymphokine to
its specific cell receptor. Instead, they can inhibit the expression of HLA-DR antigens induced by IFN-γ on U937 cells and
interfere, in mixed lymphocyte culture, with the proliferation of lymphocytes and the generation of cytotoxic lymphocytes.
Experiments in animal models suggest that natural antibodies to IFN-γ may have a role in the immunoregulatory process limiting
the intensity and/or duration of immune response. As they can interfere only with the immunomodulating activities of IFN-γ,
these antibodies might open up new therapeutic approaches to diseases with evidence of activated cell-mediated immunity. 相似文献
10.
Behnaz Valipour Kobra Velaei Ali Abedelahi Mohammad Karimipour Masoud Darabi Hojjatollah Nozad Charoudeh 《Journal of cellular physiology》2019,234(11):19352-19365
Natural killer (NK) cells have significant capability in tumor immune-surveillance. The ability of lyse transformed cells immediately in an antigen-independent manner make them an attractive candidate for cancer cell therapy. Despite employment of NK cells in cancer immunotherapy, clinical trials are faced with serious limitations such as trouble with the penetration of NK cells in tumor sites, limited in vivo persistence, and tumor microenvironment interference. Taken together, the NK-cell cancer therapy is still infant scenario that has a long way to be translated in clinic. Current article first reviews characteristic features of NK lymphocytes. Then, it discusses about important disruptive barriers and motivator in the developmental stages of NK cells like as tumor microenvironment. Finally, some revolutionary approaches are highlighted utilizing of NK cells in cancer therapy. 相似文献