坐式八段锦联合足三里穴位按压对社区高龄衰弱患者效果分析

摘要 目的：探讨坐式八段锦联合足三里穴位按压对社区高龄衰弱患者效果分析。方法：前瞻性纳入2021年3月至2022年3月南京某社区50例高龄衰弱患者为研究对象,分为两组,对照组进行常规治疗及健康指导,观察组以对照组为基础,进行为期12周的坐式八段锦锻炼及足三里穴位按压,应用简化营养食欲问卷（SNAQ）、匹兹堡睡眠质量指数表（PSQI）、Tilburg衰弱量表、汉密尔顿焦虑量表（HAMA）和抑郁量表（HAMD）和SF-36生活质量评定量表评估干预前后两组患者的食欲、睡眠、衰弱、焦虑情绪、抑郁情绪和生活质量状况。结果：干预前,两组患者HAMA、HAMD评分、躯体衰弱维度、心理衰弱维度、社会衰弱维度、总分评分、食欲、睡眠、握力和各维度生活质量评分比较无差异（P＞0.05）;干预后,两组HAMA和HAMD评分均降低,且观察组较对照组低（P<0.05）;干预后,两组躯体衰弱维度、心理衰弱维度、社会衰弱维度、总分评分均降低,且观察组较对照组低（P<0.05）;干预后,两组食欲、睡眠均降低,而握力升高,且观察组食欲、睡眠均低于对照组,而握力高于对照组（P<0.05）;干预后,两组各维度生活质量评分均升高,且观察组较对照组高（P<0.05）。结论：社区高龄衰弱患者采用坐式八段锦联合足三里穴位按压干预,可有效改善食欲促进睡眠质量升高和促进衰弱病情转归,进而有利于调节患者负性情绪和促进预后生活质量改善。     

右美托咪定联合经皮穴位电刺激对混合痔剥扎术后患者肠胃功能及术后疼痛的影响

摘要 目的：探讨右美托咪定联合经皮穴位电刺激对混合痔剥扎术后患者肠胃功能及术后疼痛的影响。方法：选择2022年3月-2022年7月我院行混合痔剥扎术的患者60例,将60例患者随机分为对照组（30例）与观察组（30例）,对照组患者给予右美托咪定镇痛,观察组给予术前经皮穴位电刺激,时间为手术开始前2 min至手术结束,右美托咪定使用方法、剂量同对照组。对比两组患者术前、术后0.5 h、1 h、2 h、3 h的疼痛评分,对比两组患者的术后疼痛疗效,对比两组创面愈合时间、腐肉完全脱落时间、住院时间及胃肠功能恢复情况,对比两组术前、术后的血管活性肠肽、胃动素及胃泌素水平。结果：术前及术后3 h时,两组的疼痛评分对比无统计学意义（P>0.05）;术后0.5 h、1 h、2 h时,观察组的疼痛评分明显较对照组低（P<0.05）。观察组的术后疼痛有效率明显较对照组高,P<0.05。观察组的创面愈合时间、腐肉完全脱落时间及住院时间明显较对照组低（P<0.05）。观察组的肠鸣音恢复时间、术后恶心呕吐发生率及排气时间明显较对照组短（P<0.05）。术前,两组的血管活性肠肽、胃动素及胃泌素水平对比无统计学意义（P>0.05）;术后,两组血管活性肠肽、胃泌素水平升高,胃动素水平降低,且观察组变化幅度明显较对照组低（P<0.05）。结论：右美托咪定联合经皮穴位电刺激可改善混合痔剥扎术后患者肠胃功能及术后疼痛情况。     

Sex differences in the Ilia of a known sex and age sample of fetal and infant Skeletons

Ilia from a known sex, race, and age sample of fetal and infant skeletons from the collections of the Smithsonian Institution were evaluated for six metric and one nonmetric characters. Three indices calculated from the measurements were analyzed. The nonmetric trait was examined for fit with known sex. The three indices failed to show significant sex differences. The nonmetric trait, Auricular Surface Elevation, proved dependable (91% accurate) for the male Fetal and Six Month age groups.     

经皮穴位电刺激联合全身麻醉对腹腔镜结直肠癌根治术患者炎性因子、T细胞亚群和认知功能的影响

摘要 目的：探讨经皮穴位电刺激（TEAS）联合全身麻醉对腹腔镜结直肠癌根治术患者炎性因子、T细胞亚群和认知功能的影响。方法：选取2018年6月~2019年9月期间我院收治的行腹腔镜结直肠癌根治术患者90例,根据随机数字表法分为对照组（n=45）和研究组（n=45）,对照组给予全身麻醉处理,研究组在对照组的基础上联合TEAS,比较两组患者炎性因子、T细胞亚群、认知功能及疼痛情况。结果：研究组术后1 d、术后5 d白介素-6（IL-6）、白介素-1（IL-1）和肿瘤坏死因子-α（TNF-α）低于对照组（P<0.05）。研究组术后1 d、术后5 d CD3⁺、CD4⁺/CD8⁺、CD4⁺高于对照组,CD8+则低于对照组（P<0.05）。研究组术后1 d、术后3 d、术后5 d、术后7 d简易智力状态检查表（MMSE）评分高于对照组（P<0.05）。研究组术后6 h、术后12 h、术后24 h、术后48 h视觉模拟评分法（VAS）评分低于对照组（P<0.05）。两组术后5 d、术后7 d认知功能障碍（POCD）发生率比较差异无统计学意义（P>0.05）;研究组术后1 d、术后3dPOCD发生率低于对照组（P<0.05）。结论：TEAS联合全身麻醉治疗腹腔镜结直肠癌根治术患者,可降低炎性反应,减轻免疫抑制,同时还可降低对机体认知功能的损害。     

经皮穴位电刺激对老年髋关节置换术患者脑氧代谢以及术后认知功能、镇痛效果的影响

目的:探讨经皮穴位电刺激(TEAS)对老年髋关节置换术患者脑氧代谢以及术后认知功能、镇痛效果的影响。方法:选取2016年1月～2018年7月期间我院收治的行髋关节置换术患者91例为研究对象,将研究对象根据随机数字表法分为对照组(n=45)和研究组(n=46),对照组给予常规麻醉处理,研究组在对照组基础上给予TEAS,比较两组脑氧代谢、术后认知功能以及镇痛效果,记录两组术后的不良反应发生情况。结果:在降压开始后20 min(T1)、降压开始后40 min(T2)、停止降压后20 min(T3)时间点时,两组静脉血氧含量(Cjv O2)较降压前即刻(T0)时间点升高,且研究组高于对照组(P0.05),两组脑动-静脉血氧含量差(Da-jvO2)、脑氧摄取率(CERO2)较T0时间点降低,且研究组低于对照组(P0.05)。两组患者术后72h简易智能量表(MMSE)评分均较术前24h降低,但研究组高于对照组(P0.05),研究组术后认知功能障碍(POCD)发生率低于对照组(P0.05)。与术前比较,两组患者术后8h、术后24h、术后48h视觉疼痛模拟量表(VAS)评分均升高(P0.05),但研究组术后8h、术后24h、术后48h等时间点VAS评分均低于对照组(P0.05)。两组患者不良反应总发生率比较无差异(P0.05)。结论:TEAS对老年髋关节置换术后患者的镇痛效果确切,可有效改善脑氧代谢情况,提高术后认知功能,临床应用价值较高。     

大鼠压杆行为的运动皮层局部场电位研究

目的：提取与大鼠右前肢运动相关联的初级运动皮层场电位的信号特征,并探讨依据局部场电位（LFP）识别前肢运动行为的可行性。方法：4只SD大鼠通过训练习得压杆取水操作,然后在左右脑初级运动皮层M1区分别植入多通道束状微电极,术后恢复后进行大鼠压杆行为实验,以2 kHz/s速率记录深部脑电信号及压杆状态信号,同步记录行为过程的视频信号。以通道间的差分信号作为局部场电位信号,分析局部场电位信号的时域特征,进行聚类分析。以压杆状态信号和视频分析为判定依据,对聚类结果进行分析。结果：局部场电位信号在大鼠压杆动作时明显增强,不同通道的局部场电位信号幅值、波形有差异,表明与前肢运动相关联的M1区局部场电位信号有空间分布特征;依据阈值准则从局部场电位信号检测压杆行为的检出率为80%。结论：依据局部场电位信号特征对大鼠前肢运动进行检测具有可行性。     

Bulk cellulose plastic materials from processing cellulose powder using back pressure-equal channel angular pressing

Bulk cellulose plastic materials with a continuous morphology were successfully processed from cellulose powder through back pressure-equal channel angular pressing (BP-ECAP) at 150 °C without using any additives. The strong shear deformation during the process caused an efficient deformation of cellulose granular and crystalline structures, resulting in effective chain penetration and strong intermolecular interactions throughout the whole material. The mechanical behaviour of the cellulose plastics was comparable to those of polymer/cellulose composites. Ball milling the cellulose powder prior to processing disrupted the crystalline structures thus resulting in more significant modifications of the molecular motions of the cellulose. The outcome of this research provides a potential methodology for manufacturing renewable and biodegradable bulk materials from cellulose-based agricultural waste.     

Model acupuncture point:Bone marrow-derived stromal stem cells are moved by a weak electromagnetic field

AIM To show the existence of a structural formative role of magnetic fields(MFs) with respect to biological objects by using our proposed model of an acupoint.METHODS We introduced a magnetised 10-100 μT metal rod(needle) into culture dishes with a negatively charged working surface and observed during 24 h how cells were arranged by MFs and by electrical fields(EFs) when attached. Rat and human bone marrow-derived stromal stem cells(r BMSCs and h BMSCs), human nonadherent mononuclear blood cells, NCTCs and A172 cells, and Escherichia coli(E. coli) were evaluated. The dish containing BMSCs was defined as the model of an acupoint. r BMSCs proliferative activity affected by the needle was investigated. For investigating electromagnetic field structures, we used the gas discharge visualisation(GDV) method.RESULTS During 24 h of incubation in 50-mm culture dishes, BMSCs or the nonadherent cells accumulated into a central heap in each dish. BMSCs formed a torus(central ring) with an inner diameter of approximately10 mm only upon the introduction of the needle in the centre of the dish. The cells did not show these effects in 35- or 90-mm culture dishes or hydrophobic dishes or rectangular cuvettes. NCTCs and A172 cells showed unstable the effects and only up to two weeks after thawing. Moreover, we observed that the appearance of these effects depended on the season. In winter, BMSCs showed no the effects. GDV experiments revealed that the resonant annular illumination gradually formed from 10 to 18-20 s in polar solutions with and without cell suspension of BMSCs, NCTCs and E. coli when using circular 50-mm dishes, stimulation at 115 V and switching of the electrode poles at 1 kH z. All these data demonstrate the resonant nature of the central ring. Significant influence of MFs on the rB MSC proliferation rate was not observed.CONCLUSION BMSCs can be moved by MFs when in the presence of a constant EF and MF, when the cells are in the responsive functional state, and when there is a resonant relationship between them.     

Enhanced insulin sensitivity using electroacupuncture on bilateral Zusanli acupoints (ST 36) in rats

In this study, intravenous glucose tolerance test (ivGTT) and insulin challenge test (ICT) were applied to evaluate the influence of electroacupuncture (EA) on insulin sensitivity in rats. Firstly, hypoglycemic activity was confirmed on normal Wistar rats (36+/-12%) and streptozotocin (STZ)-induced diabetic rats (13+/-8%) after 60 min of 15 Hz EA on bilateral Zusanli acupoints. The rats were divided into the experiment group (EG) and control group (CG) randomly. After fasting, plasma glucose and insulin levels were assayed in the normal Wistar rats undergoing ivGTT. Plasma glucose levels and hypoglycemic activity were also evaluated in the normal Wistar rats and STZ diabetic rats during ICT. As the data showed, EA improved the glucose tolerance from 15 to 90 min (p<0.005 compared with the plasma glucose levels of the CG) during ivGTT. In addition, significant improvement in the Homeostasis Model Assessment (HOMA) index was found in the EG from 15 to 90 min (p<0.005 compared with the CG). More hypoglycemic activity was achieved in normal Wistar and STZ diabetic rats in the EG than in the CG (from 30 to 60 min) during ICT. In conclusion, the results suggest that 15 Hz EA at bilateral Zusanli acupoints improved glucose tolerance. Thus, EA should be considered as an alternative method for improving insulin sensitivity and/or increase insulin-hypoglycemic activity in rats.     

改良手术方法治疗耳廓假性囊肿的疗效分析

目的:评价改进耳廓假性囊肿手术方法后治疗耳廓假性囊肿的疗效。方法:选择2011年2月至2012年7月在我科住院治疗耳廓假性囊肿患者56例,并将其随机分为常规手术组和改进手术组,观察和比较两组患者手术治疗后的痊愈率、显效率及总有效率。结果:所有病人经门诊随访半年以上。常规组1例痊愈(4.6%),4例显效(18.2%),16例有效(72.3%),1例无效(4.6%),总有效率95.5%(21/22);改进组24例痊愈(70.6%),9例显效(26.5%),1例有效(2.9%),总有效率100%(34/34),两组的痊愈率比较差异有显著性意义(P0.05),改进手术组的痊愈率显著高于常规手术组;两组的显效率比较差异有显著性意义(P0.05),改进手术组的显效率显著高于常规手术组;两组的总有效率比较差异没有有显著性意义(P0.05)。结论:改进耳廓假性囊肿手术方法后,术后术腔的渗液明显减少,缩短了换药时间,加快了伤口愈合的速度,避免了手术后因反复换药刺激引起耳廓机化、皮肤增厚而导致的耳廓变形。