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811.
The human gut microbiota comprises approximately 100 trillion microbial cells and has a significant effect on many aspects of human physiology including metabolism, nutrient absorption and immune function. Disruption of this population has been implicated in many conditions and diseases, including examples such as obesity, inflammatory bowel disease and colorectal cancer that are highlighted in this review. A logical extension of these observations suggests that the manipulation of the gut microbiota can be employed to prevent or treat these conditions. Thus, here we highlight a variety of options, including the use of changes in diet (including the use of prebiotics), antimicrobial-based intervention, probiotics and faecal microbiota transplantation, and discuss their relative merits with respect to modulating the intestinal community in a beneficial way. 相似文献
812.
JAN ŠOBOTNÍK GILLES LEPOINT JEAN‐MICHEL MARTIN OLIVIER J. HARDY ALAIN DEJEAN YVES ROISIN 《Ecological Entomology》2011,36(2):261-269
1. In the current ecological classification of termites, four feeding groups (I–IV) are recognised, corresponding to a gradient of decomposition from sound wood to highly mineralised organic matter in the soil. 2. Nitrogen stable isotopes (hereafter δ15N) were used to place termites from French Guiana rainforests along a wood‐soil decomposition gradient, to test (i) whether feeding group assignation based on morphological characters was accurate and actually represented diet specialisation thresholds, and (ii) to what extent the dietary specialization of species is explained by phylogeny (phylogenetic autocorrelation). 3. δ15N values vary over a range of 13‰, suggesting that diet diversification contributes to the high species diversity in French Guiana. δ15N values span a similar interval in all Termitidae subfamilies. Ranges of different subfamilies broadly overlap, although each of them diversified preferentially on one side of the wood‐soil decomposition gradient. Congeneric species share similar feeding habits, whereas distant species tend to feed on distinct substrates. 4. Feeding groups did not completely match stable isotope data: there was no discontinuity between Groups III and IV, and no correlation between anatomical criteria used to distinguish these groups and δ15N values. Nor was there any consistent difference in δ15N values between wood feeders of the families Rhinotermitidae (Group I) and Termitidae (Group II). We also suggest that species feeding outside the wood‐soil gradient should be distinguished for their peculiar feeding requirements. 相似文献
813.
G. A. Daneri A. R. Carlini A. Harrington L. Balboni C. M. Hernandez 《Polar Biology》2008,31(11):1365-1372
The diet of non-breeding male Antarctic fur seals, Arctocephalus gazella, was investigated at Stranger Point, King George Island, through the analysis of scats during three consecutive summer seasons
(1996, 1997, 1998). Overall, fish and krill were the most frequent prey occurring, respectively, in an average of 82.9% and
78.8% of samples (n = 131), followed by penguins (22.8%) and cephalopods (17.8%). Myctophids constituted almost 90% of the fish predated, with
Electrona antarctica and Gymnoscopelus nicholsi being the most abundant and frequent species consumed. All fish taxa identified were krill feeding species suggesting that
seals foraged mainly on a krill and a fish community associated with krill aggregations. However, a seasonal change was observed
in the relative proportions of the different prey taxa, with a progressive decrease with time in the occurrence of krill and
a concomitant increase of fish, penguins and squid. Possible influence of the strong 1997/98 ENSO event is discussed. 相似文献
814.
P F Puech F Cianfarani F Ribot i Trafi 《American journal of physical anthropology》1989,80(3):305-312
The three functional domains of the upper canines of Dryopithecus from Spain are analysed through microscopic examination. Evidence is presented that shows a food choice in concordance with open woodland habitat. 相似文献
815.
William J. Sutherland Clive W. Anderson 《Biological journal of the Linnean Society. Linnean Society of London》1987,30(2):99-114
We consider the idea that foraging animals seek to achieve a certain threshold intake of food per day rather than maximising mean energy intake. Earlier experiments and theoretical work have shown that under these conditions animals should respond to variance in reward. We identify six possible sources of such variance and produce models for five of them (the sixth is already solved). These models describe (1) whether to feed in habitats possessing small or large prey, (2) whether to feed on clumped or dispersed prey, (3) which prey items to eat, (4) the effects of misidentification of prey selection, (5) whether to feed singly or join a flock and (6) when to move between patches when the travel time between them is variable. The results are often radically different from those of traditional models and we discuss their biological significance. 相似文献
816.
Summary Deoxyfructosylserotonin (DFS), a stable derivative of serotonin, was shown to have an anti-leprosy effect (Mester and Antia). Therefore, a tryptophan-enriched food (NAL) was devised to increase the concentration of free tryptophan as serotonin precursor in blood.32 multibacillary lepromatous leprosy patients were divided in 3 groups receiving: 1) MDT (multi-drug therapy, control — 8 patients), 2) NAL (50 g/day — 13 patients) and 3) NAL + 1/2 MDT (11 patients). The clinical improvement (clinical score) was 24.2% for 1), 19.9% for 2) and 30.4% for 3). The loss of viability of theM. leprae bacilli in the mouse foot-pad test was 66% for 1), 75% for 2) and 70% for 3). The improvement by serodiagnosis (ELISA) was 19.4% for 1), 25.1% for 2) and 23.3% for 3).These preliminary results (6 months) suggest that the NAL-food is efficient against leprosy and apparently not very different from the control MDT in that respect. 相似文献
817.
Summary The diet composition of Brent Geese Branta bernicla on a salt-marsh was quantified. Puccinellia maritima was the principal food species, while Plantago maritima and Triglochin maritima were less commonly taken. Festuca rubra only acted as a substitute for Puccinellia when production of the latter species dropped. The metabolizable energy of the food plants ranged from 5 to 11 kJ·g–1. By assessing the ingestion rates of geese feeding on different food species, the net intake rate could be derived. Plantago and Triglochin appeared to be the most profitable plants to eat. The proportion of these species in the diet was restricted by (1) the capacity of the alimentary tract, since high intake rates combined with high water contents of the food plants easily led to overfill; and (2) the limited distribution of these plants, in combination with their rapid depletion by grazing geese. These latter factors led to an unequal allocation among individual geese. Most Plantago and Triglochin was obtained by dominant pairs within the flocks. The high quality of Puccinellia allowed geese to gain mass in spring, but the metabolizable energy of this plant species declined during the staging period, and Plantago and Triglochin increased in importance in supplying the geese with components with which to build their body reserves. The timing of the onset of spring growth of the various food species differed between years, and plant phenology was shown to have a profound effect on the final body reserves of the geese. 相似文献
818.
Spatial distribution of fruit-eating birds and fruiting shrubs of the Melastomataceae and Rubiaceae were examined on a 10 ha plot in tropical lowland wet forest of Costa Rica. Many plant species and most birds exhibited considerable spatial variation in their occurrence on the plot, as indicated by the distribution patterns of shrubs with ripe fruits and captures in mist nets, respectively. In many cases, captures of fruit-eating birds were correlated with abundance of fruiting plants, particularly for species that rely heavily on fruits. In general, fruit-eating birds concentrated their use of the plot to areas rich in fruiting shrubs. This differential use of certain areas likely results in differential visitation to fruiting plants located in these areas and in a heterogeneous dissemination of seeds into the habitat. 相似文献
819.
R. Casaux A. Baroni A. Ramón A. Carlini M. Bertolin C. Y. DiPrinzio 《Polar Biology》2009,32(2):307-310
A total of 14 scats of the Leopard Seal were collected on ice floes close to Cierva Point, Danco Coast, Antarctic Peninsula,
during February and March 2000. Krill was the most frequent and numerous prey and also constituted the bulk of the diet; penguins
and fish followed in importance by mass. Among fish, Gobionotothen gibberifrons was the most frequent prey and also predominated by mass whereas the myctophid Gymnoscopelus nicholsi was the most numerous prey. The results are compared with previous studies and the differences in the composition of the
diet observed among the Leopard Seal and other seals at the study area are discussed. 相似文献
820.
Hansjoerg Moest Andreas P. Frei Indranil Bhattacharya Matthias Geiger Bernd Wollscheid Christian Wolfrum 《Biochimica et Biophysica Acta (BBA)/Molecular and Cell Biology of Lipids》2013,1831(7):1208-1216
Increased triglyceride accumulation in adipocytes caused by a misbalance between energy intake and energy consumption, results in increased adipocyte size, excess adipose tissue, increased body weight and ultimately, obesity. It is well established that enlarged adipocytes exhibit malfunctions that contribute to whole body insulin resistance, a key factor for the development of type 2 diabetes. However, the underlying molecular cause for dysfunctional adipocyte behavior and signaling is poorly understood. Since the adipocyte cell surface proteome, or surfaceome, represents the cellular signaling gateway to the microenvironment, we studied the contribution of this subproteome to adipocyte malfunctions in obesity. By using the chemoproteomic Cell Surface Capture (CSC) technology, we established surfaceome maps of primary adipocytes derived from different mouse models for metabolic disorders. Relative quantitative comparison between these surfaceome maps revealed a set of cell surface glycoproteins with modulated location-specific abundance levels. RNAi mediated targeting of a subset of the detected obesity modulated cell surface glycoproteins in an in vitro model system provided functional evidence for their role in adiponectin secretion and the lipolytic activity of adipocytes. Thus, we conclude that the identified cell surface glycoproteins which exhibit obesity induced abundance changes and impact adipocyte function at the same time contribute to adipocyte malfunction in obesity. The regulation of their concerted activities could improve adipocyte function in obesity. 相似文献