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Huzheng Yan Zhanwang Xiang Zhihui Zhong Zhiqiang Mo Tao Zhang Guanyu Chen Fujun Zhang Fei Gao 《Translational oncology》2017,10(1):90-98
PURPOSE: We aimed to evaluate the feasibility and clinical effectiveness of CT-guided 125I brachytherapy for distant oral and maxillofacial metastases. MATERIALS AND METHODS: We retrospectively analyzed 65 patients with 84 distant oral and maxillofacial metastases. Thirty-one patients with 38 lesions received 125I brachytherapy (group A) and 34 with 46 lesions received external beam radiotherapy (EBRT; group B). RESULTS: Median follow-up time was 16 months. The 3-, 6-, 12-, 18-, and 24-month local control rates for group A were 83.9%, 75.9%, 66.7%, 38.4%, and 25.0%, respectively; for group B they were 76.5%, 62.5%, 43.8%, 25.0%, and 0.0%, respectively (P < .05); the median local tumor progression-free survival times were 14 and 9 months, respectively. Group A had a better local tumor progression-free survival (LTPFS) relative to group B (P < .001; HR, 6.961 [95%CI, 2.109, 9.356]). Cox proportional hazards regression analysis indicated that 125I brachytherapy, tumor size, and primary pathological type were the independent factors affecting LTPFS. Additionally, 125I brachytherapy showed better performance in relieving patient clinical symptoms relative to EBRT (P < .05). Group A also had fewer complications than group B, especially regarding grade 3/4 complications according to Radiation Therapy Oncology Group grading criteria. Mean overall survival times in groups A and B were 17.1 and 14.8 months, respectively. CONCLUSION: CT-guided 125I brachytherapy is feasible and safe for distant oral and maxillofacial metastases; it achieved a better local control rate, longer LTPFS and fewer complications without compromising overall survival compared with EBRT. 相似文献
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甘肃高原毛茛一新变种 总被引:1,自引:0,他引:1
甘肃产高原毛茛-新变种,兴隆山毛茛Ranumculus tanguticus(Maxim.) Ovcz.var.xinglongshanicus Z.X.Penget Y.J.Zhang Var.now. 相似文献
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云南报春花属(报春花科)一新变种--长萼铁梗报春 总被引:1,自引:0,他引:1
报道了云南报春花属一新变种,即长萼铁梗报春Primula sinolisteri Balf.f.var.longicalyx D.W.Xue&C.Q.Zhang。新变种与原变种的不同之处在于:花冠喉部具环状附属物,外面无毛,花萼与冠筒近等长,长7—10mm。 相似文献
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芸香草和西昌香茅挥发油的化学成分张荣,苏中武,李承祜(第二军医大学药学院,上海200433)关键词芸香草,西昌香茅,挥发油ChemicalconstituentsofessentialoilsfromCymbopogondistons(NeesexS... 相似文献