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321.
Experiments with dry, fluidized spores were conducted in a test apparatus to delineate the extent of spore contamination and
deposition behavior under normal airflow conditions within a ventilation system. The surrogate biological warfare agent used
in experiments was the spore-forming bacterium Bacillus atrophaeus. Viable-spore-counting methods were used in the study because they provide the most important number for estimating human
health effects. Three common ventilation duct materials were evaluated: flexible plastic, galvanized steel, and internally
insulated fiberglass. Transport efficiency ranged from 9 to 13% in steel and fiberglass ducts; transport efficiency was far
less (0.1–4%) in plastic duct. Results showed that the deposition of surrogate biological warfare agent was significantly
different in the three duct materials evaluated. All experimentally determined, dimensionless deposition velocities were in
the range of theoretical predictions for dimensionless roughness, k
+=10. All were 10–100 times greater than the velocities predicted for ducts with smoother surfaces, k
+=0.1. For plastic duct, greater dimensionless deposition velocities were likely the result of charge forces between spores
and surface. However, for the steel duct, a relatively large dimensionless deposition velocity was unexpected. These findings
imply that building contamination will likely vary, depending on the specific type of duct material used throughout an affected
area. Results of this study may aid in refining existing particle-transport models and remediation activities. 相似文献
322.
J. Madureira M. C. M. Alvim-Ferraz S. Rodrigues C. Gonçalves M. C. Azevedo E. Pinto 《人类与生态风险评估》2009,15(1):159-169
The purpose of this study was: (i) to characterize the school indoor environment; (ii) to evaluate self-reported prevalence of disease symptoms among Portuguese teachers; and (iii) to evaluate, as far as we know for the first time in Portugal, the impact of the indoor air quality of schools on the prevalence of disease symptoms among teachers. The study was performed in the city of Oporto, starting in 2004; it included the analysis of questionnaires fulfilled by schoolteachers (n = 177), walkthrough surveys of schools grounds, buildings, and individual classrooms (n = 76), as well as indoor air monitoring. Respirable particle increase was related to chalk use and CO2 concentrations widely exceeded reference values. Schools located near traffic lines presented higher benzene and toluene concentrations. The guideline for total viable microorganism concentration was exceeded in 35.6% of classrooms. Significant increases in disease symptoms among teachers could be related to poor indoor air quality, which was mainly due to inefficient ventilation and influence of traffic emissions. Statistically significant correlations were found between central nervous system injuries and the levels of CO2 and total volatile organic compounds, and between upper respiratory problems and mucosal irritation and the levels of TVOC and respirable particles. 相似文献
323.
Exposure to contaminants below lethal concentrations may affect the performance of organisms, resulting in measurable differences in behavior. We measured the response of the benthic invertebrate Gammarus pulex (Crustacea, Amphipoda) to sublethal concentrations of three pharmaceuticals, fluoxetine, ibuprofen and carbamazepine, and the cationic surfactant cetyltrimethylammonium bromide (CTAB). Responses in behavior during exposure were analyzed using the multivariate method of Principal Response Curves (PRC). The PRC results show that exposure to low pharmaceutical concentrations (range 1–100 ng/l) resulted in increased ventilation, whereas exposure to control or to high concentrations (1 μ g/l–1 mg/L) resulted in increased locomotion. Exposure to CTAB resulted in decreased locomotion and increased ventilation at increasing concentrations. The results of our experiments indicate that increased ventilation can be used as a general sign of stress, but not necessarily an early warning signal for mortality. 相似文献
324.
Pronounced seasonal and daily oxygen concentration changes are characteristic for Amazonian floodplain lakes. Studies on the fish fauna of the Lago Camaleão, Solimões River, Amazonas, Brazil, showed several fish species which are able to survive prolonged periods of heavy hypoxia. Twenty species belonging to eight families were observed in the laboratory in order to determine their respiratory adaptations to hypoxic conditions and oxygen concentrations at which the fish present respiratory adaptations. Finally, the fish species were distributed throughout the habitats of Lake Camaleão according to their adaptation responses. Ten fish species used the surface water for aquatic surface respiration, four species used atmospheric oxygen for aerial respiration, four species used oxygen supplied by the exudation of the roots of floating macrophytes and two exhibited a high tolerance to hypoxic conditions, and well-developed physiological biochemical mechanisms. The fish fauna is well adapted to low oxygen concentrations. The large variety of morpho-anatomical adaptations associated with biochemical and physiological mechanisms to tolerate hypoxic and anoxic conditions enable the 20 fish species to exploit several habitats of Lago Camaleão, such as floating aquatic macrophyte meadows, open water and near the shoreline. 相似文献
325.
James L. Sumich 《Marine Mammal Science》2021,37(3):870-887
A bioenergetic model is developed from empirically derived equations of morphometric, ventilatory and thermoregulatory variables to compare estimated field metabolic rates (FMR) of gray whale calves to estimates of unregulated body heat losses and consequent required thermogenesis at birth, natal lagoon departure, and weaning. Estimates of FMR are based on rates of oxygen consumption. Body surface and ventilatory heat fluxes are evaluated separately, then combined to estimate minimum total heat losses from birth to weaning at three ambient water temperature regimes typical of winter natal lagoons and Oregon coastal waters and arctic conditions during summer. Modeled heat losses of neonates in winter lagoons are half their estimated mean FMR. Neonates in good body condition appear to be capable of tolerating heat losses experienced in 10°C water without additional thermogenic activities above their estimated resting metabolic rates. This study provides new evidence that no thermoregulatory advantage accrues to neonates or to their mothers by being born in warm winter natal lagoons or by remaining there several weeks longer than other gray whales. Consequently, avoidance or reduced risk of killer whale predation seems a more likely candidate than reduced heat loss as the principal fitness benefit of low-latitude winter migrations. 相似文献
326.
东莨菪碱抑制呼吸效应及其机制 总被引:1,自引:0,他引:1
本文给兔侧脑室、犬椎动脉以及静脉注射东莨菪碱,从呼吸频率、潮气量、通气量及血气分析多项指标皆观察到东莨菪碱有明显抑制作用,且存在剂量依赖关系。东茛菪碱尚能拮抗毛果靶香碱的呼吸效应,但不能拮抗6β-乙酰氧基去甲托烷呼吸抑制效庆,反而起协同作用。上述结果提示示东莨菪碱引起呼吸抑制可能与民呼吸中枢M1受体有关。 相似文献
327.