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31.
An exact Markov chain model is formulated and computed for random mating in a haploid gamete pool. There are two versions
of the gamete, and there is a finite number of diploid monoecious organisms. The founder population is given, and the subsequent
generations allow a prescribed statistical distribution over different population sizes. The non-homogeneous Markov chain
works on the haploid gamete level provided the probability of self-fertilization is 1/n, where n is the number of diploid individuals. Standard deviations of gamete frequencies and fixation probabilities are calculated.
Effective population sizes for different population size distributions are estimated, including periodic bottlenecks. 相似文献
32.
Genetic characteristics of sei whales, Balaenoptera borealis, inhabiting the western North Pacific were analyzed at 17 microsatellite loci in a total of 89 whales obtained from the area
between 37°N–45°N and 147°E–166°E in 2002 (N = 39) and 2003 (N = 50). All the loci analyzed were polymorphic over the samples, some of the loci had more than 10 alleles, indicating a high
level of genetic variation within samples. No significant deviation from the expected Hardy–Weinberg genotypic proportion
was observed at the 17 loci in the samples. No evidence of genetic heterogeneity in allele frequencies was observed between
sexes within samples as well as between the two temporally different samples, indicating a single population of sei whales
inhabiting the western North Pacific. We finally tested and demonstrated that the population appeared not to suffer from genetic
bottleneck as a result of population decline from past commercial whaling. 相似文献
33.
Phillip C. Watts Stephen J. Kemp Ilik J. Saccheri David J. Thompson 《Ecological Entomology》2005,30(5):541-547
Abstract. 1. Good conservation management is underpinned by a thorough understanding of species' historical and contemporary dispersal capabilities along with the possible adaptive or neutral processes behind any spatio-temporal genetic structuring. These issues are investigated with respect to the rare damselfly Coenagrion mercuriale (Charpentier) – the only odonate species currently listed in the U.K.'s Biodiversity Action Plan – in east Devon where its distribution has become fragmented.
2. The two east Devon C. mercuriale populations, only 3.5 km apart, have accumulated strong differences in frequencies of alleles at 14 microsatellite loci as a consequence of poor adult dispersal and drift. There is no contemporary migration between sites.
3. A genetic signature of population decline at both sites corresponds with known demographic reductions. Coenagrion mercuriale in east Devon are now significantly genetically less diverse than those from a population stronghold in the Itchen Valley.
4. Colonies would benefit from improved connectivity between areas and possibly by a transfer of individuals from other ecologically similar areas.
5. Because C. mercuriale has a semivoltine life cycle throughout the U.K., the possibility that alternate-year cohorts are reproductively isolated is explored. Genetic differentiation among cohorts is an order of magnitude less than between sites, suggesting that some larvae delay their development into adults for a year and recruit to a different cohort.
6. To our knowledge, this is the first study to document migration and gene flow between alternate-year cohorts in a species of odonate. From a conservation standpoint, the cohorts do not require separate management. 相似文献
2. The two east Devon C. mercuriale populations, only 3.5 km apart, have accumulated strong differences in frequencies of alleles at 14 microsatellite loci as a consequence of poor adult dispersal and drift. There is no contemporary migration between sites.
3. A genetic signature of population decline at both sites corresponds with known demographic reductions. Coenagrion mercuriale in east Devon are now significantly genetically less diverse than those from a population stronghold in the Itchen Valley.
4. Colonies would benefit from improved connectivity between areas and possibly by a transfer of individuals from other ecologically similar areas.
5. Because C. mercuriale has a semivoltine life cycle throughout the U.K., the possibility that alternate-year cohorts are reproductively isolated is explored. Genetic differentiation among cohorts is an order of magnitude less than between sites, suggesting that some larvae delay their development into adults for a year and recruit to a different cohort.
6. To our knowledge, this is the first study to document migration and gene flow between alternate-year cohorts in a species of odonate. From a conservation standpoint, the cohorts do not require separate management. 相似文献
34.
John C. Marshall Jr. Bruce A. Kingsbury Dennis J. Minchella 《Conservation Genetics》2009,10(2):465-476
Habitat loss and isolation is pervasive in the Midwest U.S. Wetlands are experiencing particularly dramatic declines, yet
there is a paucity of information on the genetic impacts of these losses to obligate wetland vertebrates. We quantified the
genetic variation of extant populations of a shallow wetland specialist and evaluated potential reductions in population size
(i.e. bottlenecks) using seven polymorphic microsatellite DNA markers. We analyzed 228 copperbelly water snakes (Nerodia erythrogaster neglecta), representing populations from three states. Moderate genetic differentiation exists among all three regions (F
ST = 0.12, P < 0.001), with evidence for low levels of differentiation within the federally protected Ohio region (F
ST = 0.025, P = 0.007), and moderate to strong differentiation within the Indiana region (F
ST = 0.23, P < 0.001). Furthermore, Bayesian clustering (i.e. STRUCTURE) supports the separation of the Indiana sites, both from each
other and from all other sampling sites. However, it does not support the separation of the Ohio sites from the Kentucky sites.
Differentiation among sampling sites did not appear to be related to geographic distance, but rather depended on the quality
of terrestrial corridors used for dispersal. Mode shifts in allele frequencies and excess heterozygosity tests were negative,
while M-ratio tests were nearly all positive, indicating the likelihood of historical rather than contemporary population bottlenecks.
However, potential subspecific intergradation in the Kentucky region may have artificially lowered the M-ratio, and we suggest caution when using the M-ratio approach if intergradation is suspected. Our results have conservation implications for wetland management and management
of the copperbelly populations, and emphasizes the importance of protecting wetland complexes. 相似文献
35.
Sanne Boessenkool Sabrina S. Taylor Carolyn K. Tepolt Jan Komdeur Ian G. Jamieson 《Conservation Genetics》2007,8(3):705-714
For conservation purposes islands are considered safe refuges for many species, particularly in regions where introduced predators
form a major threat to the native fauna, but island populations are also known to possess low levels of genetic diversity.
The New Zealand archipelago provides an ideal system to compare genetic diversity of large mainland populations where introduced
predators are common, to that of smaller offshore islands, which serve as predator-free refuges. We assessed microsatellite
variation in South Island robins (Petroica australis australis), and compared large mainland, small mainland, natural island and translocated island populations. Large mainland populations
exhibited more polymorphic loci and higher number of alleles than small mainland and natural island populations. Genetic variation
did not differ between natural and translocated island populations, even though one of the translocated populations was established
with five individuals. Hatching failure was recorded in a subset of the populations and found to be significantly higher in
translocated populations than in a large mainland population. Significant population differentiation was largely based on
heterogeneity in allele frequencies (including fixation of alleles), as few unique alleles were observed. This study shows
that large mainland populations retain higher levels of genetic diversity than natural and translocated island populations.
It highlights the importance of protecting these mainland populations and using them as a source for new translocations. In
the future, these populations may become extremely valuable for species conservation if existing island populations become
adversely affected by low levels of genetic variation and do not persist. 相似文献
36.
Helen W. Nathan Mick N. Clout Jamie W. B. MacKay Elaine C. Murphy James C. Russell 《Population Ecology》2015,57(2):363-371
The ability of invasive species to recurrently establish populations from small numbers of founders, while threatened species struggle at the same low population sizes, is a paradox in conservation biology. Little is known about the mechanisms contributing to the post-arrival success of low density invasive populations as most invasive species research focuses on established, high density populations. Experimental studies are powerful, but generally limited to laboratory or invertebrate experiments. Here, we experimentally demonstrate that vertebrate mammal invasion from a very small (n = 2) number of founders follows relatively simple deterministic predictions. An intentional island invasion of introduced house mice (Mus musculus Linnaeus) from one founding pair closely tracked the density dependent logistic growth curve and reached the seasonal carrying capacity of a previously extant population in only 5 months. Carrying capacity reflected both density dependent and independent processes. In contrast to the previously incumbent population, the invading population retained a marked genetic signal of its recent founder event, but the populations were otherwise demographically indistinguishable. Stochastic events such as individual variability, supplemental immigration and ecological release, but not Allee effects, played important roles during colonisation, but following establishment dynamics rapidly became deterministic, with little demographic impact of reduced genetic diversity. The small population paradigm appears to have little influence on the population dynamics of highly successful invasive species. 相似文献
37.
《Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)》2016,32(11):1383-1396
Liver segmentation from abdominal computed tomography (CT) volumes is extremely important for computer-aided liver disease diagnosis and surgical planning of liver transplantation. Due to ambiguous edges, tissue adhesion, and variation in liver intensity and shape across patients, accurate liver segmentation is a challenging task. In this paper, we present an efficient semi-automatic method using intensity, local context, and spatial correlation of adjacent slices for the segmentation of healthy liver regions in CT volumes. An intensity model is combined with a principal component analysis (PCA) based appearance model to exclude complex background and highlight liver region. They are then integrated with location information from neighboring slices into graph cuts to segment the liver in each slice automatically. Finally, a boundary refinement method based on bottleneck detection is used to increase the segmentation accuracy. Our method does not require heavy training process or statistical model construction, and is capable of dealing with complicated shape and intensity variations. We apply the proposed method on XHCSU14 and SLIVER07 databases, and evaluate it by MICCAI criteria and Dice similarity coefficient. Experimental results show our method outperforms several existing methods on liver segmentation. 相似文献
38.
Alejandro P. Rooney Rodney L. Honeycutt Scott K. Davis James N. Derr 《Journal of molecular evolution》1999,49(5):682-690
A size-selected Balaena mysticetus genomic library was screened for clones containing simple sequence repeat, or microsatellite, loci. A total of 11 novel loci
was identified. These loci were combined with a set of 9 published loci, for a total of 20 markers, and were scored across
a sample of 108 bowhead whales from the Bering–Chukchi–Beaufort Seas population of bowhead whales. Genetic variability was
measured in terms of polymorphism information content values and unbiased heterozygosity. From the latter, estimates of long-term
effective population size were obtained. In addition, gametic phase disequilibrium among loci was investigated. Moderate to
high levels of polymorphism were found overall, and the long-term effective size estimates were large relative to total population
size. Tests of heterozygosity excess (Cornuet and Luikart 1996) and allele frequency distribution (Luikart et al. 1998) indicated
that the possibility of a recent genetic bottleneck in the Bering–Chukchi–Beaufort Seas population of bowhead whales is highly
unlikely. However, the fact that five loci displayed a statistically significant heterozygote deficiency remains to be explained.
Received: 3 November 1998 / Accepted: 28 April 1999 相似文献
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40.
The Japanese macaques (Macaca fuscata yakui) on Yakushima Island are an endemic subspecies and are closely related to the population of Kyushu, one of the main islands of Japan. Using feces collected throughout Yakushima Island, we examined mitochondrial DNA (mtDNA) to investigate the phylogeography of Japanese macaques. Six haplotypes were observed for a 203-bp fragment of the mtDNA control region. The nucleotide diversity () was low (0.0021). The genetic divergence within the Yakushima population was lower (0.009) than that among four haplotypes of the Kyushu population (0.015), calculated using Kimuras two-parameter method. The mismatch distribution analysis of the six haplotypes of the Yakushima population suggested that the Yakushima population had experienced a sudden expansion in population size, which could be related to the bottleneck effect. The geographic distribution of the mtDNA haplotypes was not uniform. One haplotype was distributed widely, whereas the other five haplotypes were distributed only in the lowlands. The low genetic diversity and biased distribution are discussed in relation to an environmental crash caused by ancient volcanic activity near this island, which is postulated to have happened about 7,300 years ago, and the delayed recovery of highland vegetation. 相似文献