纤维素生物转化过程工程的研究

虽有上百年的研究历史，但至今木质纤维素原料的低成本、大规模生物转化仍没有实现。导致这一问题的主要原因在于：纤维素生物转化涉及多个学科，是一个系统工程，目前往往从单一学科或单一技术的角度来研究，缺乏与原料相适应的集成工程技术。     

Delivery of Functionality in Complex Food Systems: Physically Inspired Approaches from Nanoscale to Microscale,Wageningen 18–21 October 2009

The Wageningen Delivery of Functionality symposium covered all aspects involved with food structural design to arrive at high-quality foods which meet demanding customer expectations and regulatory requirements. The symposium integrated aspects from the structural organization of foods at molecular and supramolecular scales to dedicated techniques required to describe and visualize such structures, the gastro-intestinal events and how to model these in a laboratory setting, and finally the impact those food structures and ingredients have on the consumer’s physiology and on the human perception. As an interdisciplinary platform, bringing together more than 160 researchers from academia and industry, the symposium meanwhile fulfills an important role in the food science community.     

鼻腔通气动力学的研究

人类的鼻腔是一个顶窄底宽,前后径大于左右径的不规则狭长腔隙。正常的鼻呼吸依赖于鼻腔适当的阻力。吸入的空气抵达鼻阈即分成层流和紊流,前者是进行气体交换的主要部分。鼻腔的诸多几何参数是影响鼻腔通气的主要因素,如鼻腔最小横截面积(ｎａｓａｌｍｉｎｉｍａｌｃｒｏｓｓｓｅｅｔｉｏｎａｌａｒｅａ,ＮＭＣＡ)鼻腔容积(ｎａｓａｌｃａｖｉｔｙｖｏｌｕｍｅ,ＮＣＶ)、鼻腔最小横截面积到前鼻孔的距离(ｄｉｓｔａｎｃｅｏｆｔｈｅｍｉｎｉｍａｌｃｒｏｓｓｓｅｃｔｉｏｎａｌａｒｅａｔｏｔｈｅｎｏｓｔｒｉｌ,ＤＣＡＮ)。人们为求得准确…     

耐药细菌蛋白质的分泌——新抗攻击的靶点

几十年来,由于抗生素的大量使用,导致了细菌对很多药物的抗药性.为了克服细菌的抗药性问题,需要用新的思路去发掘新的抗生素,包括发掘细菌细胞中存在的抗生素作用的新靶点.蛋白质的分泌过程对于细菌是生死攸关的,它可能成为新药物的适合靶点.     

双手双足并指(趾)多指(趾)多掌(蹠)骨畸形家系的分析

遗传性多指并指畸形国内已有报道,均属常染色体显性遗传。我们发现了一个呈性连锁显性遗传的双手双足并指(趾)多指(趾)多掌(蹠)骨畸形的家系,现报告如下。 一、家系调查 先证者罗××,女,25岁,其家系成员分布在怀化市及郊区公社,世代务农,家系中无     

Psychiatric Molecular Genetics and the Ethics of Social Promises

A recent literature review of commentaries and ‘state of the art’ articles from researchers in psychiatric genetics (PMG) offers a consensus about progress in the science of genetics, disappointments in the discovery of new and effective treatments, and a general optimism about the future of the field. I argue that optimism for the field of psychiatric molecular genetics (PMG) is overwrought, and consider progress in the field in reference to a sample estimate of US National Institute of Mental Health funding for this paradigm for the years 2008 and 2009. I conclude that the amounts of financial investment in PMG is questionable from an ethical perspective, given other research and clinical needs in the USA.     

Genes with expression levels correlating to drip loss prove association of their polymorphism with water holding capacity of pork

Six genes that were known to exhibit expression levels that are correlated to drip loss BVES, SLC3A2, ZDHHC5, CS, COQ9, and EGFR have been for candidate gene analysis. Based on in silico analysis SNPs were detected, confirmed by sequencing, and used for genotyping. The SNPs were genotyped in about 1,800 animals from six pig populations including commercial herds of Pietrain (PI) and German Landrace (DL), different commercial herds of Pietrain × (German Large White × German Landrace) (PIF1(a/b/c)), and one experimental F₂-population Duroc × Pietrain (DUPI). Comparative and genetic mapping established the location of BVES on SSC1, of SLC3A2 and ZDHHC5 on SSC2, of CS on SSC5, of COQ9 on SSC6 and of EGFR on SSC9, respectively, coinciding with QTL regions for carcass and meat quality traits. BVES, SLC3A2, and CS revealed association at least with drip loss and with several other measures of water holding capacity (WHC). Moreover, COQ9 and EGFR were associated with several meat quality traits such as meat color and/or thawing loss. This study reveals statistic evidence in addition to the functional relationship of these genes to WHC previously evidenced by expression analysis. This study reveals positional and genetic statistical evidence for a link of genetic variation at these loci or close to them and promotes those six candidate genes as functional and/or positional candidate genes for meat quality traits.