无菌粉针剂生产的工程控制策略解析

在经济技术的推动下,制药行业迅速发展,无菌生产的作用日益突出。但其生产过程较为复杂,对其要求极为严格,必须严格控制生产过程。在此以无菌粉针剂生产为例,先简述了其工艺特点,然后分析了整个生产过程中的质量控制。     

The RAF family：an expanding network of post—traslational controls and protein—protein interactions

Protein kinase RAF is strategically located in the “Ras-MAP-kinase signal transduction pathway“,a principle system which transmits signals from growth factor receptors to the nucleus,resulting in cell proliferation.Growth factor responses are mediated in part by activation of Ras,which in turn activates RAF to phosphorylate MEK,its downstream substrate.MEK activates MAPkinase to in fluence nuclear events.it is clear.however,that a network of signals other than those carred by Ras plays a role in RAF regulation.These orthogonal influences are mediated bu:serine/threonine kinases,tyrosine kinases,and protein-protein interactions.As a further complication to the RAF network,three isoforms of RAF have been established which have divergent N-terminal regulatory domains,Whereas these divergent regulatory domains implicate isoform-specific functions,no clear evidence or hypothesis for distinct functions for individual isoforms has been presented.Recently,“isoform-specific protein interactions“have been identified among numerous proteins interacting with RAF,These studies may serve to delineate independent functions for RAF isoforms.     

雄果蝇－神经细胞控制求爱指令

日本研究人员2011年2月10日在美国《神经元》（Neuron）杂志上报告说，他们发现了果蝇的求爱机制。如果能证实脊椎动物也有类似的机制，就有可能以此提高家畜等的繁殖效率。     

谈卫生事业单位电算化会计系统中的内部控制

伴随着科技的发展，电算化会计在各企事业单位中的普及，对内部控制制度的冲击产生了一些新问题，通过分析内部控制现状厦电算化对内部控制的影响，阐述了使其适应发展趋势的几点建议。     

唾液,涌流不息的生命之泉

<正>唾液的功能润滑作用唾液中含黏液素,可使口腔组织润滑、柔软,使其顺利地执行咀嚼、吞咽、自洁、语言等功能。     

Corrigendum to ＂The Mechanics and Trajectory Control in Locust Jumping＂ [Journal of Bionic Engineering, 2013, 10, 194-200]

This communication gives the corrigendum to the paper ＂The Mechanics and Trajectory Control in Locust Jumping＂, Journal of Bionic Engineering, 2013, 10, 194-200. doi： 10.1016/S1672-6529（13）60215-2     

水质微生物检验的质量控制

探讨影响水质微生物检验质量的因素,做好检验前、中、后的质量控制,特别是操作过程的质量控制,确保检验的准确性和可靠性。     

生命力及其尊严

在很长一段时间里，许多人认为只有动物才具有复杂的、各式各样的行为。但是现代生物学家们发现，植物能够做动物所做的一切事情，而且植物行为比动物行为具有更多的独特性、趣味性及隐秘性。植物世界有爱情也有战争，有智慧也有文化，在生物进化的长河中不断地接受、抗争、适应以及智慧地成长。