全文获取类型
收费全文 | 483篇 |
免费 | 56篇 |
国内免费 | 79篇 |
出版年
2024年 | 1篇 |
2023年 | 22篇 |
2022年 | 13篇 |
2021年 | 25篇 |
2020年 | 22篇 |
2019年 | 35篇 |
2018年 | 32篇 |
2017年 | 24篇 |
2016年 | 19篇 |
2015年 | 24篇 |
2014年 | 16篇 |
2013年 | 53篇 |
2012年 | 23篇 |
2011年 | 17篇 |
2010年 | 18篇 |
2009年 | 26篇 |
2008年 | 23篇 |
2007年 | 25篇 |
2006年 | 14篇 |
2005年 | 22篇 |
2004年 | 17篇 |
2003年 | 17篇 |
2002年 | 10篇 |
2001年 | 14篇 |
2000年 | 12篇 |
1999年 | 7篇 |
1998年 | 11篇 |
1997年 | 6篇 |
1996年 | 11篇 |
1995年 | 7篇 |
1994年 | 5篇 |
1993年 | 5篇 |
1992年 | 2篇 |
1990年 | 2篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1987年 | 1篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 4篇 |
1982年 | 3篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1979年 | 4篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1976年 | 2篇 |
1975年 | 2篇 |
排序方式: 共有618条查询结果,搜索用时 0 毫秒
611.
Evidence of a genomic insertion in intron 2 of SOD1 causing allelic drop‐out during routine diagnostic testing for canine degenerative myelopathy 下载免费PDF全文
Degenerative myelopathy is a severe and progressive neurodegenerative disease and, in the majority of breeds, is associated with the c.118G>A substitution in exon 2 of the canine superoxide dismutase 1 (SOD1) gene. Our laboratories have been engaged in determining the cause of many discordant findings between the parental and the offspring genotypes found by different laboratories. In both cases, the discordant findings refer to actual heterozygous dogs that had been typed as homozygous for the variant allele. To that aim, the genomic context of the causative variant was investigated in two Hovawart dogs. An insertion of 54 nucleotides composed of a poly‐T stretch and 15 nucleotides containing the duplication of the exon 2–intron 2 junction was found. The insertion was responsible for the partial mismatch of the reverse primer used for a direct sequencing assay. The mismatch hampered the amplification of the corresponding allele and caused an evident drop‐out effect. The insertion is in complete linkage disequilibrium with the c.118G allele. The allele containing the insertion was highly prevalent in Hovawart dogs, accounting for the 26.6% of allele frequency. The insertion was also found in other unrelated breeds such as Rough Collies and Standard Poodles. In conclusion, the study illustrates the importance of correctly designing the primers to avoid inaccurate genotyping of the degenerative myelopathy causative variant in exon 2 of the SOD1 gene. 相似文献
612.
613.
Christophe W. Patterson Jonathan P. Drury 《Biological reviews of the Cambridge Philosophical Society》2023,98(6):2012-2027
Novel biotic interactions in shifting communities play a key role in determining the ability of species' ranges to track suitable habitat. To date, the impact of biotic interactions on range dynamics have predominantly been studied in the context of interactions between different trophic levels or, to a lesser extent, exploitative competition between species of the same trophic level. Yet, both theory and a growing number of empirical studies show that interspecific behavioural interference, such as interspecific territorial and mating interactions, can slow down range expansions, preclude coexistence, or drive local extinction, even in the absence of resource competition. We conducted a systematic review of the current empirical research into the consequences of interspecific behavioural interference on range dynamics. Our findings demonstrate there is abundant evidence that behavioural interference by one species can impact the spatial distribution of another. Furthermore, we identify several gaps where more empirical work is needed to test predictions from theory robustly. Finally, we outline several avenues for future research, providing suggestions for how interspecific behavioural interference could be incorporated into existing scientific frameworks for understanding how biotic interactions influence range expansions, such as species distribution models, to build a stronger understanding of the potential consequences of behavioural interference on the outcome of future range dynamics. 相似文献
614.
Betzi Pérez-Ortega Andrew P. Hendry 《Biological reviews of the Cambridge Philosophical Society》2023,98(5):1459-1471
Free-ranging wild vertebrates need to cope with natural and anthropogenic stressors that cause short and/or long-term behavioural and physiological responses. In areas of high human disturbance, the use of glucocorticoid (GC) hormones as biomarkers to measure stress responses is an increasingly common tool for understanding how animals cope with human disturbance. We conducted a meta-analysis to investigate how human disturbances such as habitat conversion, habitat degradation, and ecotourism influence baseline GC hormones of free-ranging wild vertebrates, and we further test the role of protected areas in reducing the impact of such disturbances on these hormones. A total of 58 studies met the inclusion criteria, providing 152 data points for comparing levels of GC hormones under disturbed and undisturbed conditions. The overall effect size suggests that human disturbance does not cause a consistent increase in levels of GC hormones (Hedges' g = 0.307, 95% CI = −0.062 to 0.677). However, when the data were analysed by disturbance type, living in unprotected areas or in areas with habitat conversion were found to increase GC hormone levels compared to living in protected or undisturbed areas. By contrast, we found no evidence that ecotourism or habitat degradation generates a consistent increase in baseline GC hormone levels. Among taxonomic groups, mammals appeared more sensitive to human disturbance than birds. We advocate the use of GC hormones for inferring major human-caused contributors to the stress levels of free-ranging wild vertebrates – although such information needs to be combined with other measures of stress and interpreted in the context of an organism's life history, behaviour, and history of interactions with human disturbance. 相似文献
615.
616.
617.
618.
B. S. Goel 《Biometrical journal. Biometrische Zeitschrift》1980,22(4):345-350
In this paper systematic designs for experiments with mixtures are developed. The plan of analysis of the experiment is discussed for a quadratic model of SCHEFF É (1958) for q-component mixture with orthogonal polynomials of third degree describing the time trends. 相似文献