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961.
Michael J. Sheehan Elizabeth A. Tibbetts 《Evolution; international journal of organic evolution》2009,63(12):3106-3113
Identifying broad‐scale evolutionary processes that maintain phenotypic polymorphisms has been a major goal of modern evolutionary biology. There are numerous mechanisms, such as negative frequency‐dependent selection, that may maintain polymorphisms, although it is unknown which mechanisms are prominent in nature. Traits used for individual recognition are strikingly variable and have evolved independently in numerous lineages, providing an excellent model to investigate which factors maintain ecologically relevant phenotypic polymorphisms. Theoretical models suggest that individuals may benefit by advertising their identities with distinctive, recognizable phenotypes. Here, we test the benefits of advertising one's identity with a distinctive phenotype. We manipulated the appearance of Polistes fuscatus paper wasp groups so that three individuals had the same appearance and one individual had a unique, easily recognizable appearance. We found that individuals with distinctive appearances received less aggression than individuals with nondistinctive appearances. Therefore, individuals benefit by advertising their identity with a unique phenotype. Our results provide a potential mechanism through which negative frequency‐dependent selection may maintain the polymorphic identity signals in P. fuscatus. Given that recognition is important for many social interactions, selection for distinctive identity signals may be an underappreciated and widespread mechanism underlying the evolution of phenotypic polymorphisms in social taxa. 相似文献
962.
Voltage gated proton channels and NADPH oxidase function cooperatively in phagocytes during the respiratory burst, when reactive oxygen species are produced to kill microbial invaders. Although these molecules are distinct entities, with no proven physical interaction, their presence and activity in many cells appears to be coordinated. We describe these interactions and discuss several types of mechanisms that might explain them. 相似文献
963.
964.
Potential impact of rising seawater temperature on copepods due to coastal power plants in subtropical areas 总被引:3,自引:0,他引:3
Zhi-Bing Jiang Quan-Zhen Chen Yi-Jun Huang Xiao-Qun Xu 《Journal of experimental marine biology and ecology》2009,368(2):196-201
The major objective of this study is to understand the upper thermal limits and potential impact of temperature elevation on copepods caused by coastal power plants. Laboratory experiments were designed to evaluate the upper incipient lethal temperature (UILT) and critical thermal maximum (CTMax) of eight coastal copepod species collected from a subtropical bay in spring and summer. The 48h-UILT of copepods acclimatized at 16.0, 20.0, 28.0 °C were 26.4-29.1, 27.3-30.1, 32.9-36.9 °C, respectively. And the CTMax of copepods acclimatized at 28.0 °C was 35.80-41.03 °C. The UILT of copepods increased significantly with rising acclimatization temperatures, but the difference values between UILT and acclimatization temperatures decreased, which indicated that the seawater temperature elevation induced the growing mortalities of copepods with increasing natural seawater temperatures from the thermal addition of power plants. The results also showed that estuarine copepods had more tolerances to the thermal stress than those from other more stable marine environments. As to the calanoid copepod species, there was a significant negative correlation between the CTMax and body length (p < 0.01). So it seemed that the copepod species with large body size were more sensitive to the thermal addition than the smaller ones. Thus, owing to the temperature increase, the copepod species diversity might reduce and the composition of copepod communities might tend to be small-sized in natural sea areas close to the coastal power plants. 相似文献
965.
Mutations in the intermediate filament (IF) protein desmin cause severe forms of myofibrillar myopathy characterized by partial aggregation of the extrasarcomeric desmin cytoskeleton and structural disorganization of myofibrils. In contrast to prior expectations, we showed that some of the known disease-causing mutations, such as DesA360P, DesQ389P and DesD399Y, are assembly-competent and do allow formation of bona fide IFs in vitro and in vivo. We also previously demonstrated that atomic force microscopy can be employed to measure the tensile properties of single desmin IFs. Using the same approach on filaments formed by the aforementioned mutant desmins, we now observed two different nanomechanical behaviors: DesA360P exhibited tensile properties similar to that of wild-type desmin IFs, whereas DesQ389P and DesD399Y exhibited local variations in their tensile properties along the filament length. Based on these findings, we hypothesize that DesQ389P and DesD399Y may cause muscle disease by altering the specific biophysical properties of the desmin filaments, thereby compromising both its mechanosensing and mechanotransduction ability. 相似文献
966.
967.
968.
Nicholas J Guido Michael Baym Jonathan A Kelner Bonnie Berger James E Galagan George M Church 《Molecular systems biology》2009,5(1)
In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux–balance analysis (FBA) and bi‐level optimization have been used to great effect in aiding metabolic engineering. These methods predict the result of genetic manipulations and allow for the best set of manipulations to be found computationally. Bi‐level FBA is, however, limited in applicability because the required computational time and resources scale poorly as the size of the metabolic system and the number of genetic manipulations increase. To overcome these limitations, we have developed Genetic Design through Local Search (GDLS), a scalable, heuristic, algorithmic method that employs an approach based on local search with multiple search paths, which results in effective, low‐complexity search of the space of genetic manipulations. Thus, GDLS is able to find genetic designs with greater in silico production of desired metabolites than can feasibly be found using a globally optimal search and performs favorably in comparison with heuristic searches based on evolutionary algorithms and simulated annealing. 相似文献
969.
基于最大熵原理,针对目前对混交林测树因子概率分布模型研究的不足,提出了联合最大熵概率密度函数,该函数具有如下特点:1)函数的每一组成部分都是相互联系的最大熵函数,故可以综合混交林各主要组成树种测树因子的概率分布信息;2)函数是具有双权重的概率表达式,能体现混交林结构复杂的特点,在最大限度地利用混交林每一主要树种测树因子概率分布信息的同时,还能精确地全面反映混交林测树因子概率分布规律;3)函数的结构简洁、性能优良.用天目山自然保护区的混交林样地对混交林测树因子概率分布模型进行了应用与检验,结果表明:模型的拟合精度(R2=0.9655)与检验精度(R2=
0.9772)都较高.说明联合最大熵概率密度函数可以作为混交林测树因子概率分布模型,为全面了解混交林林分结构提供了一种可行的方法. 相似文献
0.9772)都较高.说明联合最大熵概率密度函数可以作为混交林测树因子概率分布模型,为全面了解混交林林分结构提供了一种可行的方法. 相似文献
970.
YANIS BOUCHENAK-KHELLADI † G. ANTHONY VERBOOM† TREVOR R. HODKINSON NICOLAS SALAMIN‡ OLIVIER FRANCOIS§ GRAINNE NÍ CHONGHAILE VINCENT SAVOLAINEN¶ 《Global Change Biology》2009,15(10):2397-2417
C4 grasses constitute the main component of savannas and are pervasive in other dry tropical ecosystems where they serve as the main diet for grazing animals. Among potential factors driving C4 evolution of grasses, the interaction between grasses and grazers has not been investigated. To evaluate if increased grazing pressure may have selected for higher leaf silica production as the grasses diverged, we reconstructed the phylogeny of all 800 genera of the grass family with both molecular (combined multiplastid DNA regions) and morphological characters. Using molecular clocks, we also calculated the age and number of origins of C4 clades and found that shifts from C3 to C4 photosynthesis occurred at least 12 times starting 30.9 million years ago and found evidence that the most severe drop in atmospheric carbon dioxide in the late Oligocene (between 33 and 30 million years ago) matches the first origin of C4 photosynthesis in Chloridoideae. By combining fossil and phylogenetic data for ungulates and implementing a randomization procedure, our results showed that the appearance of C4 grass clades and ungulate adaptations to C4 -dominated habitats match significantly in time. An increase of leaf epidermal density of silica bodies was found to correspond to postulated shifts in diversification rates in the late Miocene [24 significant shifts in diversification ( P <0.05) were detected between 23 and 3.7 million years ago]. For aristidoid and chloridoid grasses, increased grazing pressure may have selected for a higher leaf epidermal silica production in the late Miocene. 相似文献