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201.
M. Levy M. O. Susswein A. J. Susswein 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1993,172(6):749-758
Much of the neural circuitry controlling respiratory pumping in Aplysia has been well characterized, but the function of this movement is incompletely understood. To gain insight into possible functions of respiratory pumping, responses were examined for a 40 min exposure to two stimuli that modulate the movement: 1) increase and 2) decrease in seawater concentration. Thresholds were present for both stimuli to affect respiratory pumping. Above threshold, there were graded increases in the number of pumps elicited. There were decrements in respiratory pump frequency as a function of time exposed to the stimulus. Increased respiratory pumping did not contribute to volume regulation in response to exposure to altered seawaters, but was associated with increased defensive responses, such as escape locomotion (swimming) and inking. In addition, head shock, a well-established noxious stimulus, elicited temporal patterns of respiratory pumping similar to those elicited by altered seawaters. The data indicate that in our experimental conditions, respiratory pumping is elicited as part of an integrated defensive response to noxious seawaters. 相似文献
202.
P. Gal J. J. J. Smit A. Adiyaman A. R. Ramdat Misier P. P. H. M. Delnoy A. Elvan 《Netherlands heart journal》2015,23(2):96-99
IntroductionThe endoscopic laser balloon ablation system (EAS) is a relatively novel technique to perform pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF). The present study aimed to report the results of the first 50 patients treated in the Netherlands with the EAS in terms of procedural characteristics and AF-free survival.MethodsFifty patients successfully underwent EAS PVI. Median follow-up was 17 months. Mean age was 56 years, 82 % had paroxysmal AF.Results99 % of the pulmonary veins were successfully isolated with the EAS. Mean procedure time was 171 min and mean fluoroscopy time was 36 min. One procedure was complicated by a temporary phrenic nerve palsy (2 %). During follow-up, 58 % of patients remained free of AF without the use of antiarrhythmic drugs.ConclusionPVI with EAS is associated with a low risk of complications and a medium-term AF-free survival comparable with other PVI techniques.
Electronic supplementary material
The online version of this article (doi:10.1007/s12471-014-0624-y) contains supplementary material, which is available to authorized users. 相似文献203.
P. L. MILLER 《Physiological Entomology》1993,18(4):379-388
Abstract. Larvae of most stadia of Calopteryx splendens (Harris) have been shown to pump water in and out of the rectum for much of the time. In each cycle of pumping there are from three to seven inhalant stokes which progressively fill the ileum with water. A short pause intervenes before a strong compression of segments 5–8 expels the water in a jet. The pattern resembles the gulping ventilation of aeshnid and libellulid dragonfly larvae. Larvae made hypoxic or otherwise stressed show a rise in the frequency and amplitude of pumping. The increase in frequency is brought about by a reduction of the pause duration, while the gain of amplitude results from a rise in both the number of inhalations/cycle and the magnitude of the stroke volume of each inhalation. Some evidence concerning the role of stretch receptors in the execution of the cycle is presented. It is proposed that rectal pumping promotes the exchange of ions and dissolved gases between the rectal water and the hindgut epithelia, supplying mainly the chloride-absorbing cells in the rectal pads. Pumping also stirs the water in the vicinity of the caudal lamellae which are probably the insect's major sites of gaseous exchange. 相似文献
204.
205.
Jin‐Ming Hwang Chieh‐His Wu Wei‐Wen Kuo Gwo‐Ping Jong Chao‐Hung Lai Chang‐Hai Tsai Fuu‐Jen Tsai Mu‐Hsin Chang Jia‐Ping Wu Chih‐Yang Huang 《Cell biochemistry and function》2012,30(5):390-394
To investigate the changes of cardiomyocyte inflammation and fibrosis factors in heart of carotid artery balloon injury inflammatory rat model. Using rat carotid artery balloon injury model to detect left ventricular characteristics at 2 h, 2 days and 14 days after surgery using hematoxylin‐eosin (H&E) gross stain, Masson's trichome stain and Western blot analysis for inflammatory and fibrosis‐induced factors, tumour necrosis factor α (TNFα), JNK1, P38α, connective tissue growth factor (CTGF), SP1 and transforming growth factor β (TGFβ) protein expressions. The rat carotid arteries were injured after 2 h, 2 days and 14 days. Balloon‐angioplasty to H&E stain results showed the increasing trend of left ventricular wall at 2 h and 2 days; then, the left ventricular wall became thinner, and the left ventricular chamber became enlarged and dilated after 14 days of carotid artery balloon injury. In addition, the Masson's trichome stain results showed that the left ventricular section has fibrosis‐related blue staining (collagen) at 2 and 14 days after rat carotid artery balloon injury, and became even more severe at 14 days. Furthermore, we observed the protein expression level changs, which include TNFα, JNK1, P38α, CTGF, SP1 and TGFβ using Western blotting assay. All proteins were induced at 2 h, 2 days and then reached the maximal level at 14 days. The vessel inflammation was associated with cardiac inflammatory and fibrosis effects during or after carotid artery balloon injury. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
206.
We designed a water pumping system based on double-walled carbon nanotube. In this system, the inner tube was fixed as the water channel, while the exterior was moved similarly to the piston motion along the axial direction to induce pumping force. Molecular dynamics simulations confirmed that the water flux is sensitive to the motion velocity of the outer tube so that giant and controllable unidirectional water flow can be achieved in this system by varying the velocity. The enhancement of the pumping ability mainly results from the carbon–water van der Waals driving forces of the exterior tube and the osmosis pressure of the water reservoir. This design may open a new way for water pumping in the field of nanodevices. 相似文献