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171.
172.
Jiří Doskočil 《Journal of molecular evolution》1996,42(5):512-524
The evolutionary past of intragenic repeats in protein-coding exons of c-, N-, L-, and s-myc-protooncogene subfamilies was elucidated. Apparently these genes evolved by succession of distinct unit events rather than
by a steady flow of random point mutations. An evolutionary event probably involved a duplication of the whole gene, which
was followed by amplification of progressively shorter oligonucleotide themes and motifs. The repeats were either joined in
tandem or one of the copies was transposed and integrated elsewhere within the same exon. In some instances multiple fragments
of an amplified theme were integrated at several sites. Direct repeats were found to prevail over inverted ones. By reconstructing
the fate of repeats in the course of evolution of vertebrates, the origins of some functional domains could be traced to the
initial amplification event. For example, an N-myc-specific domain was created by tandem duplication of a single-copy theme of L-myc exon; at the time of divergence of the c-myc and N-myc, the tandem duplex underwent a new round of duplication followed by transposition of the new copy, thus accounting for the
formation of a new domain specific for c-myc. The model proposed here may be regarded as a molecular-level equivalent of the theory of punctuated equilibria.
This is the author's last paper; it was submitted shortly before his death. The proofs were corrected by Michal Dvorak
Correspondence to: M. Dvorak 相似文献
173.
174.
耗散结构理论与其他热力学概念一起,可以解释生态学中的许多现象。生态系统是耗散系统,用耗散结构理论来分析和讨论生态平衡等问题更为合理、准确。等级系统理论是为理解和研究高度复杂系统而发展起来的系统理论。等级系统理论为研究生态系统的行为和特征提供了客观的、适用的概念构架和实践指南,并为生态系统科学的统一性理论的形成开辟了广阔前景。本文拟就耗散结构理论和等级系统理论的主要内容及其在生态学中的应用作一介绍和讨论。 相似文献
175.
The formation of two new groups of sooty mangabeys (N=6; N=11) comprised of individuals removed from their natal group of
98 animals led to dominance rank challenges with aggression and wounding, though this occurred after an interval of months.
Dominance rank challenges were not expected because, unlike rhesus macaques, adult female sooty mangabeys do not affiliate
with adult kin significantly more than nonkin and show minimal agonistic aiding even with adult kin, thus rank would seem
to be independent of aiding. Moreover, during the last nine years, severe wounding of adults in a large stable group of sooty
mangabeys has been virtually absent and agonistic behavior in a stable group of sooty mangabeys is exhibited at a low rate
compared to some macaque species. New members in the group of six maintained their relative ranks for 12 weeks after which
the beta supplanted the alpha female with no serious wounding. This ranking remained stable for 29 weeks after which the alpha
and beta females were supplanted with fatal wounds inflicted to the alpha and less severe wounds to the beta female. The second
subgroup also kept their relative ranks initially. However, after 27 weeks the lowest ranking female severely wounded the
next to last ranking female and 1 week later attacked and displaced the alpha female with minimal wounding. Fourteen weeks
later the beta female (formerly the alpha) attacked and severely wounded the new alpha female and regained the top dominance
position. These events suggest that although sooty mangabeys do not exhibit strong kin preferential behavior among adults,
they do have defined relationships within the long term, stable group. Removal from those defined relationships allows the
possibility of social reorganization that may be mediated by serious aggression. 相似文献
176.
Social dominance and interrenal cell activity in rainbow trout,Salmo gairdneri (Pisces,Salmonidae) 总被引:1,自引:0,他引:1
Synopsis The relationship between standing in a dominance hierarchy and physiological stress was studied in rainbow trout. Individual fish were assigned relative dominance ranks, based on behavioral observations in a large, simulated stream tank. These ranks were compared to histometric measures of interrenal cell activity. Fish, isolated individually in the stream tank had significantly lower levels of interrenal activity than fish from the crowded holding tank. Groups of fish in the stream tank formed stable, linear dominance hierarchies. Interrenal activity correlated inversely with dominance rank, with the exception that top ranking fish had higher activity than expected. Possible cause and effect relationships are discussed. 相似文献
177.
Two classes of tests for the hypothesis of bivariate symmetry are studied. For paired exponential survival times (t1j, t2j), the classes of tests are those based on t1j-t2j and those based on log t1j–log t2j. For each class the sign, signed ranks, t and likelihood ratio tests are compared via Pitman's criterion of asymptotic relative efficiency (ARE). For tests based on t1j — t2j, it is found that: (1) the efficacy of the paired t depends on the coefficient of variation (CV) of the pair means, (2) the signed rank test has the same ARE to the sign test as for the usual location problem. For tests based on log t1j — log t2j, the ARE comparisons reduce to the well-known results for the one-sample location problem for samples from a logistic density. Hence, the signed rank test is asymptotically efficient. Furthermore, analyses based on log t1j — log t2j are not complicated by the underlying pairing mechanism. 相似文献
178.
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180.