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蛋白质与酶工程是生物技术专业的核心、必修课程,在专业人才培养体系中具有重要地位。文中以教育部颁布的《高等学校课程思政建设指导纲要》为依据、结合专业及课程特色,科学设定教学目标,深入挖掘课程思政教育元素,从融入内容、方法路径及评价等方面进行了课程思政教学改革的探索和实践。通过精心开展教学设计,利用对分课堂、以学生为中心,从讲故事、谈生活、说案例、议热点、读文献、做训练入手,激发并培养学生的科学精神、公民品格、全球视野、生态文明、法治意识、家国情怀和文化自信素养,促进课程思政教育有机融入教学全过程,实现课程育人目标的同时推动教学卓越。 相似文献
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目的分析互联网教育对超声专业住培医师教学的影响。方法将我科接受超声专业住院医师规范化培训的50名住培医师为研究对象,其中以2019年1~4月的住培医师为对照组,以2020年1~4月的住培医师为实验组。对照组以传统教学方式教学,实验组以互联网教学为主要教学方式,两组住培医师通过考试成绩(笔试及技能)及问卷调查方法评估不同时期超声规范化培训的教学效果结果实验组的笔试和技能考核成绩低于对照组(P<0.05),考试通过率低于对照组(P<0.05)。从两组的问卷调查结果显示,实验组的住培医师认为在激发学习兴趣、提升交流能力、提高技能操作、满意带教老师、师生互动良好5个方面的肯定评价低于对照组(P<0.05);两组住培医师在关注人文关怀、临床思维培养2个方面比较,差异无统计学意义(P>0.05);两组在培养自学能力方面的肯定评价比较,实验组明显高于对照组(P<0.05)。与对照组比较,教师对实验组的教学气氛活跃、住培医师态度积极性及检查操作规范、报告书写规范4个方面的评价较低(P<0.05);教师对两组的课程安排与进度合理性的评价无差异性(P>0.05)。结论短期研究结果显示,以互联网教学为主的教学方式对超声住培教学质量造成一定负面影响,需加以教育经验总结,为今后教学工作的改进奠定基础。 相似文献
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IMPROV-ED trial: eHealth programme for faster recovery and reduced healthcare utilisation after CABG
van Steenbergen G. J. van Veghel D. ter Woorst J. van Lieshout D. Dekker L. 《Netherlands heart journal》2021,29(2):80-87
Netherlands Heart Journal - After coronary artery bypass grafting (CABG), healthcare utilisation is high and is partly unplanned. eHealth applications have been proposed to reduce healthcare... 相似文献
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Foreign health aid forms a substantial portion of health spending in many low- and middle-income countries (LMICs). It can be either vertical (funds earmarked for specific diseases) or horizontal (funds used for broad health sector strengthening). Historically, most health aid has been disbursed vertically toward key infectious diseases, with minimal allocations to noncommunicable diseases (NCDs). High NCD burden in LMICs underscores a need for increased assistance toward NCD objectives, but evidence on the outcomes of health aid for NCDs is sparse. We obtained annual data on cause-specific deaths and disability-adjusted life years (DALYs) for four leading NCDs across 116 countries, 2000–2016, and evaluated the relationship between these indicators and vertical and horizontal health aid using country fixed-effects models with 1-to-5-year lagged effects. After adjusting for fixed and time-variant country heterogeneity, vertical assistance for NCDs was significantly associated with subsequent reductions in NCD morbidity and mortality, particularly for persons under age 70 and for cardiovascular and chronic respiratory diseases. An additional dollar in per-capita NCD vertical assistance corresponded to reductions in the average annual NCD burden of 7,459 DALYs/281 deaths after one year, 7,728 DALYs/319 deaths after two years, and 8,957 DALYs/346 deaths after three years. The findings suggest that vertical assistance for NCD programs may be an appropriate mechanism for addressing short-term NCD needs in LMICs, where it may help to fill health sector gaps in NCD care, but longer-term evaluation is needed for assessing the role of horizontal assistance. 相似文献
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CRISPR/Cas9是新兴的基因编辑技术,在生命科学研究中发挥着重要的作用。将它引入本科生的实验教学,使本科生了解这项前沿科研技术很有意义。我们创建了一个基于CRISPR/ Cas9技术的本科教学实验体系。该实验体系侧重CRISPR/Cas9技术在哺乳动物细胞中的应用,选用一株基因组上被插入mCherry基因的小鼠胚胎成纤维细胞为实验材料,命名为STO-82。首先设计靶向mCherry的sgRNA,构建CRISPR-Cas9/sgRNA共表达质粒。经测序验证无误后,转染到STO-82细胞。采用流式细胞仪分析检测mCherry阴性和阳性两群细胞,分选出阴性单细胞并扩大培养。最后用测序检验单克隆细胞中靶标DNA序列的编辑情况。结果显示,靶位点有插入或缺失突变,说明体系创建成功。该实验体系将sgRNA设计、CRISPR-Cas9/sgRNA共表达质粒的构建、细胞转染、单细胞分选、单克隆细胞培养、测序序列分析等内容融合为一个综合实验,用于高年级本科生的实验教学。根据实际情况,将教学实践内容分解分块教学,也可以做完整性项目教学。本教学实践采用10人左右的小班分块教学,2人一组,经过3个班(共13组)的实践,绝大部分学生都能完成实验,得到预期结果。通过这个实验,学生加深了对CRISPR/Cas9技术的原理和实验流程的理解,锻炼了实验操作能力和严谨的科研思维,也使学生对该技术的医疗应用风险有了一些认识。 相似文献
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Saraswathi Umavathi Shahid Mahboob Marimuthu Govindarajan Khalid A. Al-Ghanim Zubair Ahmed P. Virik Norah Al-Mulhm Murugesh Subash Kasi Gopinath C. Kavitha 《Saudi Journal of Biological Sciences》2021,28(3):1808-1815
The present work aims to synthesize zinc oxide (ZnO) nanoparticles via green approaches using leaf extract of Parthenium hysterophorus. UV–vis and FT-IR tests confirmed the existence of biomolecules, active materials, and metal oxides. The X-ray diffraction structural study exposes the ZnO nanoparticles formation with hexagonal phase structures. SEM and TEM analysis reveal surface morphologies of ZnO nanoparticles and most of them are spherical with a size range of 10 nm. ZnO nanoparticles were revealed strong antimicrobial activity against both bacterial and fungal strains. The germination of seeds and vegetative growth of Sesamum indicum has been greatly improved. 相似文献
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Khalid Ghilan Asim Mehmood Zafar Ahmed Ahmed Nahari Mohammed J. Almalki Abdulrahman M. Jabour Fahad khan 《Saudi Journal of Biological Sciences》2021,28(1):643-650
BackgroundEfficiency remains one of the most important drivers of decision making in health care system. Fund allocators need to receive structured information about the cost healthcare services from hospitals for better decisions related to resource allocation and budgeting. The objective of the study was to estimate the unit cost for health services offered to inpatients in King Fahd Central hospital (KFCH) Jazan during the financial year 2018.MethodsWe applied a retrospective approach using a top-down costing method to estimate the cost of health care services. Clinical and Administrative departments divided into cost centres, and the unit cost was calculated by dividing the total cost of final care cost centres into the total number of patients discharged in one year. The average cost of inpatient services was calculated based on the average cost of each ward and the number of patients treated.ResultsThe average cost per patient stayed in KFCH was SAR 19,034, with the highest cost of SAR 108,561 for patients in the Orthopedic ward. The average cost of the patient in the Surgery ward, Plastic surgery, Neurosurgery, Medical ward, Pediatric ward and Gynecology ward was SAR 33,033, SAR 29,425, SAR 23,444, SAR 20,450, SAR 9579 and SAR 8636 respectively.ConclusionThis study provides necessary information about the cost of health care services in a tertiary care setting. This information can be used as a primary tool and reference for further studies in other regions of the country. Hence, this data can help to provide a better understanding of tertiary hospital costing in the region to achieve the privatization objective. 相似文献