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171.
Abstract:  Over the past three decades Ordovician pteraspidomorphs (armoured jawless fish) have been recorded from the fringes of the Gondwana palaeocontinent, in particular Australia and South America. These occurrences are dominated by arandaspid agnathans, the oldest known group of vertebrates with extensive biomineralisation of the dermoskeleton. Here we describe specimens of arandaspid agnathans, referable to the genus Sacabambaspis Gagnier, Blieck and Rodrigo, from the Ordovician of Oman, which represent the earliest record of pteraspidomorphs from the Arabian margin of Gondwana. These are among the oldest arandaspids known, and greatly extend the palaeogeographical distribution of the clade around the periGondwanan margin. Their occurrence within a very narrow, nearshore ecological niche suggests that similar Middle Ordovician palaeoenvironmental settings should be targeted for further sampling.  相似文献   
172.
Abstract:  The taxonomy, biostratigraphical and palaeogeographical distribution of the Lower Ordovician graptolite genus Bryograptus is evaluated. Bryograptus is recognized as a distinct triradiate anisograptid with a multiramous, pendent rhabdosome. The species of the genus Bryograptus can be interpreted as shallow water faunal elements with a strongly limited biogeographical distribution to the Atlantic Faunal Realm. Bryograptus is restricted to a narrow interval in the Upper Tremadocian, the Bryograptus Biozone of Scandinavia and South America (Argentina), making it a taxon with a high potential for precise biostratigraphical correlations. The proximal end development can be used to differentiate the genus Bryograptus from other pendent multiramous graptoloid genera with a homoplastic rhabdosome development. Characteristics of the proximal end development and structure easily differentiate these genera in relief specimens, but not in flattened material.  相似文献   
173.
Abstract:  Trace fossils such as Climactichnites offer rare insights into the palaeobiology of Cambrian soft-bodied animals, especially those that inhabited emergent sand flats and are not known from body fossils. Analysis of field and museum Climactichnites , together with experiments on the preservation of similar modern trails, indicates that the tracemaker was an elongate, bilaterally symmetrical, dorsoventrally flattened, soft-bodied animal with a muscular foot. These characteristics are consistent with the tracemaker being a primitive mollusc or mollusc-like animal. Unlike most Neoproterozoic and Cambrian molluscs, the tracemaker could reach considerable size; at up to c . 69 cm long, it was one of the largest Cambrian animals of its time. When moving on the sediment surface, locomotion resulted from muscular waves generated along the sole of its flexible foot; the foot was extended and then clamped onto the substrate. Contraction of pedal muscles then pulled the body forward. Sedimentary structures associated with Climactichnites  wilsoni , such as polygonal desiccation cracks, raindrop impressions, adhesion structures and gas escape structures demonstrate that the animal inhabited intermittently subaerially exposed environments. The tracemaker's method of locomotion is similar to that employed by modern intertidal gastropods, which make Climactichnites -like trails on exposed sand flats. However, these modern trails are not preserved because of erosion by wind, waves, tides and subsequent bioturbation. Abundant microbial sedimentary structures are associated with C. wilsoni , and together with low levels of vertical bioturbation, intimate that microbial binding may have mediated the preservation of these early mollusc trails.  相似文献   
174.
Abstract:  A new neosuchian crocodylomorph, Susisuchus jaguaribensis sp. nov., is described based on fragmentary but diagnostic material. It was found in fluvial-braided sediments of the Lima Campos Basin, north-eastern Brazil, 115 km from where Susisuchus anatoceps was found, in rocks of the Crato Formation, Araripe Basin. S. jaguaribensis and S. anatoceps share a squamosal–parietal contact in the posterior wall of the supratemporal fenestra. A phylogenetic analysis places the genus Susisuchus as the sister group to Eusuchia, confirming earlier studies. Because of its position, we recovered the family name Susisuchidae, but with a new definition, being node-based group including the last common ancestor of Susisuchus anatoceps and Susisuchus jaguaribensis and all of its descendents. This new species corroborates the idea that the origin of eusuchians was a complex evolutionary event and that the fossil record is still very incomplete.  相似文献   
175.
BackgroundAcute kidney injury (AKI) is increasingly encountered in community settings and contributes to morbidity, mortality, and increased resource utilization worldwide. In low-resource settings, lack of awareness of and limited access to diagnostic and therapeutic interventions likely influence patient management. We evaluated the feasibility of the use of point-of-care (POC) serum creatinine and urine dipstick testing with an education and training program to optimize the identification and management of AKI in the community in 3 low-resource countries.Methods and findingsPatients presenting to healthcare centers (HCCs) from 1 October 2016 to 29 September 2017 in the cities Cochabamba, Bolivia; Dharan, Nepal; and Blantyre, Malawi, were assessed utilizing a symptom-based risk score to identify patients at moderate to high AKI risk. POC testing for serum creatinine and urine dipstick at enrollment were utilized to classify these patients as having chronic kidney disease (CKD), acute kidney disease (AKD), or no kidney disease (NKD). Patients were followed for a maximum of 6 months with repeat POC testing. AKI development was assessed at 7 days, kidney recovery at 1 month, and progression to CKD and mortality at 3 and 6 months. Following an observation phase to establish baseline data, care providers and physicians in the HCCs were trained with a standardized protocol utilizing POC tests to evaluate and manage patients, guided by physicians in referral hospitals connected via mobile digital technology. We evaluated 3,577 patients, and 2,101 were enrolled: 978 in the observation phase and 1,123 in the intervention phase. Due to the high number of patients attending the centers daily, it was not feasible to screen all patients to assess the actual incidence of AKI. Of enrolled patients, 1,825/2,101 (87%) were adults, 1,117/2,101 (53%) were females, 399/2,101 (19%) were from Bolivia, 813/2,101 (39%) were from Malawi, and 889/2,101 (42%) were from Nepal. The age of enrolled patients ranged from 1 month to 96 years, with a mean of 43 years (SD 21) and a median of 43 years (IQR 27–62). Hypertension was the most common comorbidity (418/2,101; 20%). At enrollment, 197/2,101 (9.4%) had CKD, and 1,199/2,101 (57%) had AKD. AKI developed in 30% within 7 days. By 1 month, 268/978 (27%) patients in the observation phase and 203/1,123 (18%) in the intervention phase were lost to follow-up. In the intervention phase, more patients received fluids (observation 714/978 [73%] versus intervention 874/1,123 [78%]; 95% CI 0.63, 0.94; p = 0.012), hospitalization was reduced (observation 578/978 [59%] versus intervention 548/1,123 [49%]; 95% CI 0.55, 0.79; p < 0.001), and admitted patients with severe AKI did not show a significantly lower mortality during follow-up (observation 27/135 [20%] versus intervention 21/178 [11.8%]; 95% CI 0.98, 3.52; p = 0.057). Of 504 patients with kidney function assessed during the 6-month follow-up, de novo CKD arose in 79/484 (16.3%), with no difference between the observation and intervention phase (95% CI 0.91, 2.47; p = 0.101). Overall mortality was 273/2,101 (13%) and was highest in those who had CKD (24/106; 23%), followed by those with AKD (128/760; 17%), AKI (85/628; 14%), and NKD (36/607; 6%). The main limitation of our study was the inability to determine the actual incidence of kidney dysfunction in the health centers as it was not feasible to screen all the patients due to the high numbers seen daily.ConclusionsThis multicenter, non-randomized feasibility study in low-resource settings demonstrates that it is feasible to implement a comprehensive program utilizing POC testing and protocol-based management to improve the recognition and management of AKI and AKD in high-risk patients in primary care.

Etienne Macedo and colleagues report on a point-of-care testing program for acute kidney injury and disease in high-risk primary care patients.  相似文献   
176.
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178.
Abstract:  The assemblage of large-bodied theropod remains from the Taynton Limestone Formation (middle Bathonian) of Stonesfield, Oxfordshire and the Chipping Norton Limestone Formation (lowest Bathonian) of New Park Quarry, Gloucestershire, UK is interpreted as monospecific. An assessment of morphological variation in theropod fossils from these localities reveals no taxonomically-significant variation among remains representing large-bodied individuals. Previous observations of anatomical variation among femora, ilia and scapulocoracoids are attributed to postmortem damage and deformation. Referral of all such material to the first named dinosaur taxon, Megalosaurus bucklandii Mantell, is therefore justified. ' Iliosuchus incognitus ' lacks autapomorphies and is a nomen dubium . However, other remains of small-bodied theropods from Stonesfield indicate a minimum of two small-bodied taxa that are distinct from M. bucklandii.  相似文献   
179.
This paper records the abstracts of the presentations given at the 11th Oamaru Penguin Symposium, held at the Opera House, Oamaru, New Zealand, 3 and 4 May, 2018.  相似文献   
180.
Abstract:  Eighteen gastropod and five bivalve species are taxonomically described from an Upper Oligocene succession cropping out near Otranto (southern Salento, Apulia, Italy). Among these, Tectarius ( Echininus ) japigiae , Hydrobia dubuissoni hydruntina , Pseudamnicola messapica , Pseudamnicola palmariggii and Stenothyrella salentina are new taxa. Nonmarine and lagoonal environments characterize almost the whole succession, as testified by species-poor assemblages rich in specimens of freshwater and oligo- to mesohaline prosobranchs, such as Neritinidae, Hydrobiidae, Stenothyridae, Thiaridae, Potamididae, Batillariidae, pulmonates, including Planorbidae and bivalves comprising Dreissenidae and Cyrenidae. The genera Theodoxus , Hydrobia , Melanoides , Potamides , Terebralia , Batillaria , Granulolabium , Mytilopsis and Polymesoda alternately dominate. Littoral marine elements, such as Tectarius , Turritella , Barbatia , Anadara and Chama , are scattered present in the succession, but some prevail towards the top. The fauna is palaeobiogeographically significant having strong affinities with those of the Oligo–Miocene basins of Aquitaine, Mainz, Bavaria, North Alpine Foreland, Vienna, Greece and Turkey. The analysed Otranto succession is assigned to the Chattian Galatone Formation of southernmost Apulia (Salento) based on lithological evidence and supported by the palaeontological data.  相似文献   
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