Enhanced Colon-Targeted Release of Propolis by pH-driven Encapsulation using Folic Acid Modified Carboxymethyl Chitosan

Food Biophysics - Propolis is a natural bioactive compound that is being explored as a nutraceutical because of its potential health benefits. In this study, propolis-loaded biopolymer...     

Regulation mechanism of lysC riboswitch in gram-positive bacterium Bacillus subtilis

Abstract

Communicated by Ramaswamy H. Sarma     

盐酸胍对口蹄疫病毒完整颗粒和空衣壳的影响

在口蹄疫病毒的复制过程中，会形成完整的病毒粒子（146S）和一定量的空衣壳（75S）。本试验研究了盐酸胍在不同时间和浓度下对口蹄疫病毒146S和75S的影响，并筛选出75S产量最高的条件。通过蔗糖密度梯度离心、透射电镜、特异性单域抗体包被的双抗夹心ELISA等方法对75S和146S进行定性和定量检测。结果表明在口蹄疫病毒（Foot-and-mouth disease virus,FMDV）感染BHK-21细胞2 h时，加入4 mmol/mL的盐酸胍，75S产量比同时间下加入盐酸胍浓度为2 mmol/mL和8 mmol/mL时得到的75S含量高两倍，约为146S的三倍。本研究为定量口蹄疫病毒75S形态的免疫学方法建立奠定了前期研究基础。     

Analysis of the distribution of chemical elements in Adelie penguin bone using synchrotron radiation X-ray fluorescence

We performed synchrotron radiation X-ray fluorescence (SR-XRF) analysis of Adelie penguin bones, collected in the maritime Antarctic. This method enabled us to determine the microscopic concentration profiles of chemical elements in transverse bone sections. Results show that: (1) there are different concentration profiles for elements in the bones; (2) the inter-correlation of elements in the bones is complex; (3) some trace elements, including toxic ones like Rb, Sr, Fe, Mn, Cu, Co, Ni, Ti, Zr, Br, As, Hg, and Cr, are also detected somewhere in the cross section of the bones. It is suggested that further studies be conducted to establish an SR-XRF database for polar and non-polar animals. This will be greatly beneficial for characterizing penguins by the microscopic distribution of elements in bone and for the understanding of elements' roles in animal metabolism.     

Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

1. Download : Download high-res image (100KB)
2. Download : Download full-size image

     

Role of joint language control during cross-language communication: evidence from cross-frequency coupling

How do bilingual interlocutors inhibit interference from the non-target language to achieve brain-to-brain information exchange in a task to simulate a bilingual speaker–listener interaction. In the current study, two electroencephalogram devices were employed to record pairs of participants’ performances in a joint language switching task. Twenty-eight (14 pairs) unbalanced Chinese–English bilinguals (L1 Chinese) were instructed to name pictures in the appropriate language according to the cue. The phase-amplitude coupling analysis was employed to reveal the large-scale brain network responsible for joint language control between interlocutors. We found that (1) speakers and listeners coordinately suppressed cross-language interference through cross-frequency coupling, as shown in the increased delta/theta phase-amplitude and delta/alpha phase-amplitude coupling when switching to L2 than switching to L1; (2) speakers and listeners were both able to simultaneously inhibit cross-person item-level interference which was demonstrated by stronger cross-frequency coupling in the cross person condition compared to the within person condition. These results indicate that current bilingual models (e.g., the inhibitory control model) should incorporate mechanisms that address inhibiting interference sourced in both language and person (i.e., cross-language and cross-person item-level interference) synchronously through joint language control in dynamic cross-language communication.     

Characteristics analysis of the complete Wurfbainia villosa chloroplast genome

Physiology and Molecular Biology of Plants - Wurfbainia villosa, which belongs to the huge family Zingiberaceae, is used in the clinic for the treatment of spleen and stomach diseases in southern...