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991.
Temporal integration of input is essential to the accumulation of information in various cognitive and behavioral processes, and gradually increasing neuronal activity, typically occurring within a range of seconds, is considered to reflect such computation by the brain. Some psychological evidence suggests that temporal integration by the brain is nearly perfect, that is, the integration is non-leaky, and the output of a neural integrator is accurately proportional to the strength of input. Neural mechanisms of perfect temporal integration, however, remain largely unknown. Here, we propose a recurrent network model of cortical neurons that perfectly integrates partially correlated, irregular input spike trains. We demonstrate that the rate of this temporal integration changes proportionately to the probability of spike coincidences in synaptic inputs. We analytically prove that this highly accurate integration of synaptic inputs emerges from integration of the variance of the fluctuating synaptic inputs, when their mean component is kept constant. Highly irregular neuronal firing and spike coincidences are the major features of cortical activity, but they have been separately addressed so far. Our results suggest that the efficient protocol of information integration by cortical networks essentially requires both features and hence is heterotic. 相似文献
992.
Munehiro Okamoto Minoru Nakao David Blair Malinee T. Anantaphruti Jitra Waikagul Akira Ito 《Parasitology international》2010,59(1):70-74
There has long been a debate as to the specific status of the cestode Taenia asiatica, with some people regarding it as a distinct species and some preferring to recognize it as a strain of Taenia saginata. The balance of current opinion seems to be that T. asiatica is a distinct species. In this study we performed an allelic analysis to explore the possibility of gene exchange between these closely related taxa. In total, 38 taeniid tapeworms were collected from humans living in many localities including Kanchanaburi Province, Thailand where the two species are sympatric. A mitochondrial DNA (mtDNA)-based multiplex PCR tentatively identified those parasites as T. asiatica (n = 20) and T. saginata (n = 18). Phylogenetic analyses of a mitochondrial cytochrome c oxidase subunit 1 (cox1) gene and two nuclear loci, for elongation factor-1 alpha (ef1) and ezrin-radixin-moesin (ERM)-like protein (elp), assigned all except two individual parasites to the species indicated by multiplex PCR. The two exceptional individuals, from Kanchanaburi Province, showed a discrepancy between the mtDNA and nuclear DNA phylogenies. In spite of their possession of sequences typical of the T. saginata cox1 gene, both were homozygous at the elp locus for one of the alleles found in T. asiatica. At the ef1 locus, one individual was homozygous for the allele found at high frequency in T. asiatica while the other was homozygous for the major allele in T. saginata. These findings are evidence of occasional hybridization between the two species, although the possibility of retention of ancestral polymorphism cannot be excluded. 相似文献
993.
994.
995.
Makoto Okamoto Yutaka Kurita Hiroya Sugisaki Takashi Asahida 《Ichthyological Research》2010,57(4):398-405
Larvae of bigmouth manefish Caristius macropus are described and illustrated on the basis of seven specimens (4.2–10.5 mm in body length) from the Kuroshio waters (0–60 m
depth) and the transition waters (surface) between the Kuroshio and Oyashio fronts of the western North Pacific. The present
larvae of C. macropus are distinguished from those of Paracaristius maderensis that inhabit the North Pacific by having 39–40 myomeres, 34 dorsal-fin rays, and 22 anal-fin rays. The present study, along
with previous studies of the early life stages of caristiids, shows that larvae of the family may be defined by the following
characters: body elongate in preflexion stage but becoming deep bodied and hatchet shaped after notochord flexion; anus located
near vertical through base of pectoral fin; head large, without spination or serration; a distinct vertical band on the posterior
tail throughout the larval stages, and two bands gradually appearing on the tail and trunk during the flexion and postflexion
stages; and melanophores present around the notochord tip by the flexion stage. Adult C. macropus are found in the subarctic and temperate waters of the North Pacific; however, the present study and other occurrences of
early life stages of the species probably indicate that C. macropus may spawn over a wide area in the North Pacific. 相似文献
996.
Takatomo Fujisawa Rei Narikawa Shinobu Okamoto Shigeki Ehira Hidehisa Yoshimura Iwane Suzuki Tatsuru Masuda Mari Mochimaru Shinichi Takaichi Koichiro Awai Mitsuo Sekine Hiroshi Horikawa Isao Yashiro Seiha Omata Hiromi Takarada Yoko Katano Hiroki Kosugi Satoshi Tanikawa Kazuko Ohmori Naoki Sato Masahiko Ikeuchi Nobuyuki Fujita Masayuki Ohmori 《DNA research》2010,17(2):85-103
997.
998.
Organization pattern of nacre in Pteriidae (Bivalvia: Mollusca) explained by crystal competition 总被引:5,自引:0,他引:5
Checa AG Okamoto T Ramírez J 《Proceedings. Biological sciences / The Royal Society》2006,273(1592):1329-1337
Bivalve nacre is a brick-wall-patterned biocomposite of aragonite platelets surrounded by organic matter. SEM-electron back scatter diffraction analysis of nacre of the bivalve family Pteriidae reveals that early aragonite crystals grow with their c-axes oriented perpendicular to the growth surface but have their a- and b-axes disoriented. With the accumulation of successive lamellae, crystals progressively orient themselves with their b-axes mutually parallel and towards the growth direction. We propose that progressive orientation is a result of competition between nacre crystals at the growth front of lamellae, which favours selection of crystals whose fastest growth axis (b-axis) is oriented parallel to the direction of propagation of the lamella. A theoretical model has been developed, which simulates competition of rhombic plates at the lamellar growth front as well as epitaxial growth of crystals onto those of the preceding lamella. The model predicts that disordered nacre progressively produces bivalve-like oriented nacre. As growth fronts become diffuse (as is the common case in bivalves) it takes longer for nacre to become organized. Formation of microdomains of nacre platelets with different orientations is also reproduced. In conclusion, not only the organic matrix component, but also the mineral phase plays an active role in organizing the final microstructure. 相似文献
999.
1000.
Spreading disease with transport-related infection 总被引:1,自引:0,他引:1
Transportation among regions is found as one of the main factors which affect the outbreak of diseases. It will change the disease dynamics and break infection out even if infectious diseases will go to extinction in each city without transport-related infection. In this paper, a mathematical model is proposed to demonstrate the dynamics of such disease propagation between two regions (or cities) due to the population dispersal and infection on transports. Further, our analysis shows that transport-related infection intensifies the disease spread if infectious diseases break out to cause an endemic situation in each region, in the sense that both the absolute and relative size of patients increase. This suggests that it is very essential to strengthen restrictions of passengers once we know infectious diseases appeared. 相似文献