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361.
Marthoni Vinicius Massaro Juliana Felden Lucas Adriano Pachla Débora Alessandra Antonetti David Augusto Reynalte-Tataje 《Zeitschrift fur angewandte Ichthyologie》2020,36(3):358-360
Length-weight relationship (LWRs) were determined for 13 fish species from the Uruguay River. The fish were caught in six locations and sampled at each location during each season, totaling 72 samplings, starting in May 2016 and ending in February 2018. Various materials were used such as gillnets (15; 20; 25 30; 40 and 80 mm, triple mesh 150.30.150 150.40.150 and 150.50.150 mm, 8 mm trawl). We also used two longlines, 100 m long, 30 hooks each (hooks 5/0 and 12/0), baited with small fish, corn and snail. Length-weight relationship were adjusted appropriately for all species (r2 > .95). The b values of the LRW equations ranged from 2.38 in Steindachnerina brevipinna to 3.62 in Pimelodus atrobrunneus. 相似文献
362.
Nicholas A. C. Marino Rafael D. Guariento Viviane Dib Fernanda D. Azevedo Vinicius F. Farjalla 《Hydrobiologia》2011,678(1):191-199
The primary goal of this study was to evaluate the relative importance of habitat physical properties, bottom-up and top-down
factors, and their interaction on algae biomass in tank-bromeliads. We sampled algae biomass (chlorophyll-a concentration),
micro-metazoan density, mosquito abundance, and several environmental variables, including nutrient concentrations and characteristics
of the habitat physical structure, in a survey of 64 tank-bromeliads of four different species (Aechmea nudicaulis, Aechmea lingulata, Neoregelia cruenta, and Vriesea neoglutinosa). We analyzed the complete and individual bromeliad species datasets using an information-theoretic model selection approach
(Akaike’s information criterion). Bromeliad species, maximum water volume, and bromeliad diameter comprised the best model
for determining chlorophyll-a concentrations for the complete dataset. The maximum water volume also comprised the best model
to explain chlorophyll-a concentrations in three of four bromeliad species datasets. Interactions between consumers and nutrient
concentration were included in the subsequent models, but they were not statistically significant. Taken together, these results
demonstrate that the impact of habitat size on the associated autotrophic biomass occurs possibly via changes in community
susceptibility to disturbances, particularly drought. We can conclude that habitat size is more important than resource availability
or herbivory on phytotelm autotrophic biomass regulation in these natural microcosms. 相似文献
363.
364.
Glaucia H. Braun Daniel M. M. Jorge Henrique P. Ramos Raquel M. Alves Vinicius B. da Silva Silvana Giuliatti 《Journal of biomolecular structure & dynamics》2013,31(4):347-355
Abstract Monoamine oxidase is a flavoenzyme bound to the mitochondrial outer membranes of the cells, which is responsible for the oxidative deamination of neurotransmitter and dietary amines. It has two distinct isozymic forms, designated MAO-A and MAO-B, each displaying different substrate and inhibitor specificities. They are the well-known targets for antidepressant, Parkinson's disease, and neuroprotective drugs. Elucidation of the x-ray crystallographic structure of MAO-B has opened the way for the molecular modeling studies. In this work we have used molecular modeling, density functional theory with correlation, virtual screening, flexible docking, molecular dynamics, ADMET predictions, and molecular interaction field studies in order to design new molecules with potential higher selectivity and enzymatic inhibitory activity over MAO-B. 相似文献
365.
Vinicius Toledo Ribas Bjrn Friedhelm Vahsen Lars Tatenhorst Veronica Estrada Vivian Dambeck Raquel Alves Almeida Mathias Bhr Uwe Michel Jan Christoph Koch Hans Werner Müller Paul Lingor 《Cell death & disease》2021,12(2)
Axonal damage is an early step in traumatic and neurodegenerative disorders of the central nervous system (CNS). Damaged axons are not able to regenerate sufficiently in the adult mammalian CNS, leading to permanent neurological deficits. Recently, we showed that inhibition of the autophagic protein ULK1 promotes neuroprotection in different models of neurodegeneration. Moreover, we demonstrated previously that axonal protection improves regeneration of lesioned axons. However, whether axonal protection mediated by ULK1 inhibition could also improve axonal regeneration is unknown. Here, we used an adeno-associated viral (AAV) vector to express a dominant-negative form of ULK1 (AAV.ULK1.DN) and investigated its effects on axonal regeneration in the CNS. We show that AAV.ULK1.DN fosters axonal regeneration and enhances neurite outgrowth in vitro. In addition, AAV.ULK1.DN increases neuronal survival and enhances axonal regeneration after optic nerve lesion, and promotes long-term axonal protection after spinal cord injury (SCI) in vivo. Interestingly, AAV.ULK1.DN also increases serotonergic and dopaminergic axon sprouting after SCI. Mechanistically, AAV.ULK1.DN leads to increased ERK1 activation and reduced expression of RhoA and ROCK2. Our findings outline ULK1 as a key regulator of axonal degeneration and regeneration, and define ULK1 as a promising target to promote neuroprotection and regeneration in the CNS.Subject terms: Cell death in the nervous system, Neurodegeneration, Spinal cord injury 相似文献