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961.
Almani Shahneela Talpur Farah Naz Memon Najma Afridi Hassan Imran 《Biological trace element research》2020,193(2):357-363
Biological Trace Element Research - The present study was undertaken to generate a database for selenium (Se) content present in minced and processed meat products abundantly available in the... 相似文献
962.
Etvi Juntunen Riikka ArppeLaura Kalliomäki Teppo SalminenSheikh M. Talha Tiina MyyryläinenTero Soukka Kim Pettersson 《Analytical biochemistry》2016
Many quantitative and semiquantitative lateral flow (LF) assays have been introduced for clinical analytes such as biomarkers for cancer or acute myocardial infarction (AMI). Various detection technologies involving quantitative analyzing devices have been reported to have sufficient analytical sensitivity and quantification capability for clinical point-of-care tests. Fluorescence-based detection technologies such as quantum dots, Eu(III) nanoparticles, and photon-upconverting nanoparticles (UCNPs) have been introduced as promising solutions for point-of-care devices because of their high detectability by optical sensors. Lateral flow assays can be used for various sample types, e.g., urine, saliva, cerebrospinal fluid, and blood. This study focuses on the properties of serum and plasma because of their relevance in cancer and AMI diagnostics. The limit of detection was compared in LF assays having Eu(III) nanoparticles or UCNPs as reporters and the antibody configurations for two different analytes (prostate-specific antigen and cardiac troponin I (cTnI)). The results indicate a significant effect of anticoagulants in venipuncture tubes. The samples in K3EDTA tubes resulted in significant interference by decreased reporter particle mobility, and thus the limit of detection was up to eightfold less sensitive compared to serum samples. Despite the matrix interference in the cTnI assay with UCNP reporters, limits of detection of 41 ng/L with serum and 66 ng/L with the Li-heparin sample were obtained. 相似文献
963.
964.
Melanoides tuberculata in the Kuala Lumpur area of Malaysia were found to be entirely female, reproducing parthenogenetically. The reproductive system is extremely simple in structure and histology, lacking all the glandular developments common in most mesogastropods. Eggs pass into a cephalic brood-pouch where they develop to juveniles of 5–6 shell whorls before emergence. Numbers of developing young in the brood-pouches increased with shell height of the parents except for a decline in the few very largest snails. The highest brood-pouch count was 265, but average counts were much lower. 85 % of developing young in the brood-pouches were very early stages from eggs to embryos of one whorl only, perhaps implying that many eggs fail to develop successfully to young snails. Three localities studied yielded consistently different brood-pouch counts, implying variation in fecundity. Juveniles emerge from the brood-pouch most commonly between nightfall and midnight and normal emergence seems to require diurnal alternation of light and dark. In continuous darkness, brood-pouch counts increased markedly, perhaps as a result of greater activity and feeding during darkness. Several features of the reproductive biology suggest that Melanoides might become a useful experimental animal in freshwater studies. 相似文献
965.
Almalki Waleed Hassan Ghoneim Mohammed M. Alshehri Sultan Imam Syed Sarim Kazmi Imran Gupta Gaurav 《Molecular and cellular biochemistry》2022,477(9):2203-2211
Molecular and Cellular Biochemistry - In individuals with sepsis-related neurodegenerative illness, sleep and circadian rhythm disturbance are common. The alteration in genomic expression linked... 相似文献
966.
Brandt M. Gibson David J. Furbish Imran A. Rahman Mark W. Schmeeckle Marc Laflamme Simon A.F. Darroch 《Biological reviews of the Cambridge Philosophical Society》2021,96(1):129-152
Over 3.7 billion years of Earth history, life has evolved complex adaptations to help navigate and interact with the fluid environment. Consequently, fluid dynamics has become a powerful tool for studying ancient fossils, providing insights into the palaeobiology and palaeoecology of extinct organisms from across the tree of life. In recent years, this approach has been extended to the Ediacara biota, an enigmatic assemblage of Neoproterozoic soft-bodied organisms that represent the first major radiation of macroscopic eukaryotes. Reconstructing the ways in which Ediacaran organisms interacted with the fluids provides new insights into how these organisms fed, moved, and interacted within communities. Here, we provide an in-depth review of fluid physics aimed at palaeobiologists, in which we dispel misconceptions related to the Reynolds number and associated flow conditions, and specify the governing equations of fluid dynamics. We then review recent advances in Ediacaran palaeobiology resulting from the application of computational fluid dynamics (CFD). We provide a worked example and account of best practice in CFD analyses of fossils, including the first large eddy simulation (LES) experiment performed on extinct organisms. Lastly, we identify key questions, barriers, and emerging techniques in fluid dynamics, which will not only allow us to understand the earliest animal ecosystems better, but will also help to develop new palaeobiological tools for studying ancient life. 相似文献
967.
Russian Journal of Bioorganic Chemistry - The abuse of antibiotics in therapy has lead to the development of resistance in the target organisms. The failure of presented antibiotics to control... 相似文献
968.
Imran Ali Lakhiar Tabinda Naz Syed Farman Ali Chandio Noman Ali Buttar 《Journal of Plant Interactions》2018,13(1):338-352
This review paper describes a novel approach to plant cultivation under soil-less culture. At present, global climate change is expected to raise the risk of frequent drought. Agriculture is in a phase of major change around the world and dealing with serious problems. In future, it would be difficult task to provide a fresh and clean food supply for the fast-growing population using traditional agriculture. Under such circumstances, the soil-less cultivation is the alternative technology to adapt effectively. The soil-less system associated with the Hydroponic and Aeroponics system. In the aeroponics system, plant roots are hanging in the artificially provided plastic holder and foam material replacement of the soil under controlled conditions. The roots are allowed to dangle freely and openly in the air. However, the nutrient rich-water deliver with atomization nozzles. The nozzles create a fine spray mist of different droplet size at intermittently or continuously. This review concludes that aeroponics system is considered the best plant growing method for food security and sustainable development. The system has shown some promising returns in various countries and recommended as the most efficient, useful, significant, economical and convenient plant growing system then soil and other soil-less methods. 相似文献
969.
Ping Wang Lin Zhou Pierce Jamieson Lin Zhang Zhixue Zhao Kevin Babilonia Wenyong Shao Lizhu Wu Roma Mustafa Imran Amin Alessandra Diomaiuti Daniela Pontiggia Simone Ferrari Yuxia Hou Ping He Libo Shan 《The Plant cell》2020,32(12):3978
Plant receptor-like kinases (RLKs) are important players in response to pathogen infections. Verticillium and Fusarium wilts, caused by Verticillium dahliae (Vd) and Fusarium oxysporum f. sp vasinfectum (Fov), respectively, are among the most devastating diseases in cotton (Gossypium spp). To understand the cotton response to these soil-borne fungal pathogens, we performed a genome-wide in silico characterization and functional screen of diverse RLKs for their involvement in cotton wilt diseases. We identified Gossypium hirsutum GhWAK7A, a wall-associated kinase, that positively regulates cotton response to both Vd and Fov infections. Chitin, the major constituent of the fungal cell wall, is perceived by lysin-motif-containing RLKs (LYKs/CERK1), leading to the activation of plant defense against fungal pathogens. A conserved chitin sensing and signaling system is present in cotton, including chitin-induced GhLYK5-GhCERK1 dimerization and phosphorylation, and contributes to cotton defense against Vd and Fov. Importantly, GhWAK7A directly interacts with both GhLYK5 and GhCERK1 and promotes chitin-induced GhLYK5-GhCERK1 dimerization. GhWAK7A phosphorylates GhLYK5, which itself does not have kinase activity, but requires phosphorylation for its function. Consequently, GhWAK7A plays a crucial role in chitin-induced responses. Thus, our data reveal GhWAK7A as an important component in cotton response to fungal wilt pathogens by complexing with the chitin receptors. 相似文献
970.
Anisomycin and cycloheximide, like growth factors, stimulate rapidly ATP turnover in 3T3 cells 总被引:1,自引:0,他引:1
Addition of EGF and insulin to quiescent cultures of 3T3 cells induce a rapid stimulation of ATP turnover. We show that, like growth factors, anisomycin and cycloheximide, two inhibitors of protein synthesis, induce in 3T3 cells, a rapid increase in ATP turnover. However, this effect was not the result of the inhibition of protein synthesis since puromycin, in the same experimental conditions, did not stimulate ATP turnover. 相似文献