全文获取类型
收费全文 | 152篇 |
免费 | 9篇 |
国内免费 | 1篇 |
出版年
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 9篇 |
2020年 | 6篇 |
2019年 | 5篇 |
2018年 | 7篇 |
2017年 | 10篇 |
2016年 | 6篇 |
2015年 | 6篇 |
2014年 | 8篇 |
2013年 | 9篇 |
2012年 | 10篇 |
2011年 | 11篇 |
2010年 | 4篇 |
2009年 | 4篇 |
2008年 | 12篇 |
2007年 | 12篇 |
2006年 | 3篇 |
2005年 | 8篇 |
2004年 | 5篇 |
2003年 | 6篇 |
2002年 | 6篇 |
1999年 | 1篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1990年 | 1篇 |
1985年 | 1篇 |
1980年 | 1篇 |
1974年 | 2篇 |
排序方式: 共有162条查询结果,搜索用时 15 毫秒
61.
Muhammad Ashfaq Ghulam Shabbir Shah Ali Raza Noor Shahida Parveen Ansari Shahid Mansoor 《Biocontrol Science and Technology》2010,20(6):625-630
A parasitic wasp, Aenasius bambawalei, was studied for its biological parameters and parasitism levels in the cotton mealybug (Phenacoccus solenopsis). Biological parameters including parasitism efficiency, time to pupation, time to eclosion and adult sex ratio were studied under lab conditions. Parasitism levels in field collected mealybug were determined using PCR. Results showed an increase in parasitism over the study period, with higher parasitism levels in 2009 compared to the preceding 2 years. 相似文献
62.
63.
64.
Substance P (SP) is well known to promote inflammation in acute pancreatitis (AP) by interacting with neurokinin-1 receptor. However, mechanisms that terminate SP-mediated responses are unclear. Neutral endopeptidase (NEP) is a cell-surface enzyme that degrades SP in the extracellular fluid. In this study, we examined the expression and the role of NEP in caerulein-induced AP. Male BALB/c mice (20-25 g) subjected to 3-10 hourly injections of caerulein (50 μg/kg) exhibited reduced NEP activity and protein expression in the pancreas and lungs. Additionally, caerulein (10(-7) M) also downregulated NEP activity and mRNA expression in isolated pancreatic acinar cells. The role of NEP in AP was examined in two opposite ways: inhibition of NEP (phosphoramidon [5 mg/kg] or thiorphan [10 mg/kg]) followed by 6 hourly caerulein injections) or supplementation with exogenous NEP (10 hourly caerulein injections, treatment of recombinant mouse NEP [1 mg/kg] during second caerulein injection). Inhibition of NEP raised SP levels and exacerbated inflammatory conditions in mice. Meanwhile, the severity of AP, determined by histological examination, tissue water content, myeloperoxidase activity, and plasma amylase activity, was markedly better in mice that received exogenous NEP treatment. Our results suggest that NEP is anti-inflammatory in caerulein-induced AP. Acute inhibition of NEP contributes to increased SP levels in caerulein-induced AP, which leads to augmented inflammatory responses in the pancreas and associated lung injury. 相似文献
65.
Life cycle assessment of mini-hydropower plants in Thailand 总被引:1,自引:0,他引:1
Wannarat Suwanit Shabbir H. Gheewala 《The International Journal of Life Cycle Assessment》2011,16(9):849-858
Purpose
The conversion of electricity in Thailand is mainly based on fossil fuels that account more than 90% of electricity generated in the country. The use of fossil fuels has large environmental impacts, and being largely imported, also affects the energy security of the country. From the oil shock situation in 1970s, there has been interest in renewable energy in Thailand resulting in the policy goal for the year 2020 to increase the portion of renewable energy to 20% of energy used in the country. Now, hydropower contributes a significant portion of the renewable energy in Thailand, and mini-hydropower (run-of-river type with capacity between 200 to 6000 kW) tends to be most attractive. This is particularly suitable for Thailand, and it is being applied at several locations. Thus, the overall life cycle assessment (LCA), from cradle to gate, of mini-hydropower plants needs to be assessed for quantitative evaluation. 相似文献66.
67.
68.
C Hindinger CC Bergmann DR Hinton TW Phares GI Parra S Hussain C Savarin RD Atkinson SA Stohlman 《PloS one》2012,7(7):e42088
Demyelination and axonal degeneration are determinants of progressive neurological disability in patients with multiple sclerosis (MS). Cells resident within the central nervous system (CNS) are active participants in development, progression and subsequent control of autoimmune disease; however, their individual contributions are not well understood. Astrocytes, the most abundant CNS cell type, are highly sensitive to environmental cues and are implicated in both detrimental and protective outcomes during autoimmune demyelination. Experimental autoimmune encephalomyelitis (EAE) was induced in transgenic mice expressing signaling defective dominant-negative interferon gamma (IFN-γ) receptors on astrocytes to determine the influence of inflammation on astrocyte activity. Inhibition of IFN-γ signaling to astrocytes did not influence disease incidence, onset, initial progression of symptoms, blood brain barrier (BBB) integrity or the composition of the acute CNS inflammatory response. Nevertheless, increased demyelination at peak acute disease in the absence of IFN-γ signaling to astrocytes correlated with sustained clinical symptoms. Following peak disease, diminished clinical remission, increased mortality and sustained astrocyte activation within the gray matter demonstrate a critical role of IFN-γ signaling to astrocytes in neuroprotection. Diminished disease remission was associated with escalating demyelination, axonal degeneration and sustained inflammation. The CNS infiltrating leukocyte composition was not altered; however, decreased IL-10 and IL-27 correlated with sustained disease. These data indicate that astrocytes play a critical role in limiting CNS autoimmune disease dependent upon a neuroprotective signaling pathway mediated by engagement of IFN-γ receptors. 相似文献
69.
Zalucki MP Shabbir A Silva R Adamson D Shu-Sheng L Furlong MJ 《Journal of economic entomology》2012,105(4):1115-1129
Since 1993, the annual worldwide cost of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae), control has been routinely quoted to be US$1 billion. This estimate requires updating and incorporation of yield losses to reflect current total costs of the pest to the world economy. We present an analysis that estimates what the present costs are likely to be based on a set of necessary, but reasoned, assumptions. We use an existing climate driven model for diamondback moth distribution and abundance, the Food and Agriculture Organization country Brassica crop production data and various management scenarios to bracket the cost estimates. The "length of the string" is somewhere between US$1.3 billion and US$2.3 billion based on management costs. However, if residual pest damage is included then the cost estimates will be even higher; a conservative estimate of 5% diamondback moth-induced yield loss to all crops adds another US$2.7 billion to the total costs associated with the pest. A conservative estimate of total costs associated with diamondback moth management is thus US$4 billion-US$5 billion. The lower bound represents rational decision making by pest managers based on diamondback moth abundance driven by climate only. The upper estimate is due to the more normal practice of weekly insecticide application to vegetable crops and the assumption that canola (Brassica napus L.) is treated with insecticide at least once during the crop cycle. Readers can decide for themselves what the real cost is likely to be because we provide country data for further interpretation. Our analysis suggests that greater efforts at implementation of even basic integrated pest management would reduce insecticide inputs considerably, reducing negative environmental impacts and saving many hundreds of millions of dollars annually. 相似文献
70.
Yuda Yulisa Restianti Shabbir H. Gheewala 《The International Journal of Life Cycle Assessment》2012,17(4):402-408