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排序方式: 共有697条查询结果,搜索用时 15 毫秒
691.
692.
David M. Arana Daniel Prieto Elvira Román César Nombela Rebeca Alonso‐Monge Jesús Pla 《Microbial biotechnology》2009,2(3):308-320
Fungal infections are a serious health problem. In recent years, basic research is focusing on the identification of fungal virulence factors as promising targets for the development of novel antifungals. The wall, as the most external cellular component, plays a crucial role in the interaction with host cells mediating processes such as adhesion or phagocytosis that are essential during infection. Specific components of the cell wall (called PAMPs) interact with specific receptors in the immune cell (called PRRs), triggering responses whose molecular mechanisms are being elucidated. We review here the main structural carbohydrate components of the fungal wall (glucan, mannan and chitin), how their biogenesis takes place in fungi and the specific receptors that they interact with. Different model fungal pathogens are chosen to illustrate the functional consequences of this interaction. Finally, the identification of the key components will have important consequences in the future and will allow better approaches to treat fungal infections. 相似文献
693.
694.
P. Joseph-Nathan J.D. Hernández L.U. Román E.G. García V. Mendoza S. Mendoza 《Phytochemistry》1982,21(5):1129-1132
Isoparvifolinone (2a), 8-hydroxypereflorine (3a) and diperezone (5) and the known sesquiterpenes cyperene and parvifoline (1a) were isolated from the roots of Perezia alamani var. oolepis. The structures of the new compounds were deduced from spectral data and tested by chemical correlation. Thus diperezone (5) was identical to the dimerization product of perezone (4a), isoparvifolinone (2a) was partially synthesized from parvifoline (1a) and 8-hydroxypereflorine (3a) was converted into the known 8-methoxypereflorine (3b). 相似文献
695.
Aida-Odette Avenda?o-Vázquez Elizabeth Cordoba Ernesto Llamas Carolina San Román Nazia Nisar Susana De la Torre Maricela Ramos-Vega María de la Luz Gutiérrez-Nava Christopher Ian Cazzonelli Barry James Pogson Patricia León 《The Plant cell》2014,26(6):2524-2537
In addition to acting as photoprotective compounds, carotenoids also serve as precursors in the biosynthesis of several phytohormones and proposed regulatory signals. Here, we report a signaling process derived from carotenoids that regulates early chloroplast and leaf development. Biosynthesis of the signal depends on ζ-carotene desaturase activity encoded by the ζ-CAROTENE DESATURASE (ZDS)/CHLOROPLAST BIOGENESIS5 (CLB5) gene in Arabidopsis thaliana. Unlike other carotenoid-deficient plants, zds/clb5 mutant alleles display profound alterations in leaf morphology and cellular differentiation as well as altered expression of many plastid- and nucleus-encoded genes. The leaf developmental phenotypes and gene expression alterations of zds/clb5/spc1/pde181 plants are rescued by inhibitors or mutations of phytoene desaturase, demonstrating that phytofluene and/or ζ-carotene are substrates for an unidentified signaling molecule. Our work further demonstrates that this signal is an apocarotenoid whose synthesis requires the activity of the carotenoid cleavage dioxygenase CCD4. 相似文献
696.
697.
S Cohen-Kaminsky L Maouche-Chrétien L Vitelli M A Vinit I Blanchard M Yamamoto C Peschle P H Roméo 《The EMBO journal》1998,17(17):5151-5160