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Yoshiyuki Tanaka Emma S. Data Shohei Hirose Takeshi Taniguchi Ikuzo Uritani 《Bioscience, biotechnology, and biochemistry》2013,77(4):693-700
Bluish fluorescent and phenolic components were produced in cassava roots in response to cut- injury, and in relation to physiological deterioration and microbial deterioration. The former roved to consist of five coumarin components, the main three of which were scopoletin, scopolin and esculin, and the other two were scopoletin- and esculetin-containing conjugates. A main component of the latter was (+)-catechin. Some enzymes pertaining to the production of the secondary metabolites such as acid invertase, phenylalanine ammonia lyase and peroxidase were formed in cut-injured tissue and in non-infected tissue adjacent to the soft-rotten part. 相似文献
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Yusuke Sakaguchi Naohiko Fujii Tatsuya Shoji Terumasa Hayashi Hiromi Rakugi Kunitoshi Iseki Yoshiharu Tsubakihara Yoshitaka Isaka the Committee of Renal Data Registry of the Japanese Society for Dialysis Therapy 《PloS one》2014,9(12)
Background
In vitro studies have shown inhibitory effects of magnesium (Mg) on phosphate-induced calcification of vascular smooth muscle cells, raising the possibility that maintaining a high Mg level may be useful for reducing cardiovascular risks of patients with hyperphosphatemia. We examined how serum Mg levels affect the association between serum phosphate levels and the risk of cardiovascular mortality in patients undergoing hemodialysis.Methods
A nationwide register-based cohort study was conducted using database of the Renal Data Registry of the Japanese Society for Dialysis Therapy in 2009. We identified 142,069 patients receiving in-center hemodialysis whose baseline serum Mg and phosphate levels were available. Study outcomes were one-year cardiovascular and all-cause mortality. Serum Mg levels were categorized into three groups (lower, <2.7 mg/dL; intermediate, ≥2.7, <3.1 mg/dL; and higher, ≥3.1 mg/dL).Results
During follow-up, 11,401 deaths occurred, out of which 4,751 (41.7%) were ascribed to cardiovascular disease. In multivariable analyses, an increase in serum phosphate levels elevated the risk of cardiovascular mortality in the lower- and intermediate-Mg groups, whereas no significant risk increment was observed in the higher-Mg group. Moreover, among patients with serum phosphate levels of ≥6.0 mg/dL, the cardiovascular mortality risk significantly decreased with increasing serum Mg levels (adjusted odds ratios [95% confidence intervals] of the lower-, intermediate-, and higher-Mg groups were 1.00 (reference), 0.81 [0.66–0.99], and 0.74 [0.56–0.97], respectively.). An interaction between Mg and phosphate on the risk of cardiovascular mortality was statistically significant (P = 0.03).Conclusion
Serum Mg levels significantly modified the mortality risk associated with hyperphosphatemia in patients undergoing hemodialysis. 相似文献55.
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P G Data W Olmi J Moschello 《Bollettino della Società italiana di biologia sperimentale》1979,55(1):18-23
A new multichannel, telemetric system for analysing biological data was developed and tested, in collaboration with the Berta Firm in Turin. This system was tested on subjects at 4650 meters in Peru. The results obtained show the usefulness of this tool. In addition it is very good in evaluating the progress of post-myocardial infarctuated patients. 相似文献
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