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D. Ohri 《Plant Systematics and Evolution》1996,200(3-4):225-232
Chromosome complements and 2C DNA amounts of six species ofTerminalia have been studied.Terminalia oliveri, T. myriocarpa andT. arjuna are diploid (2n = 24),T. chebula andT. bellirica are tetraploid (2n = 48),T. muelleri shows a triploid number (2n = 36). Two well demarcated groups of species are recognizable on the basis of chromosome length and 2C DNA values which range from 3.60 pg (T. oliveri) to 12.80 pg (T. bellirica) showing a 3.5-fold difference. Differences of DNA per basic genome or per chromosome are greatest (1.97-fold) betweenT. oliveri andT. arjuna. Two species groups (1)T. oliveri andT. chebula, and (2)T. myriocarpa, T. arjuna, T. muelleri, T. bellirica, therefore are well differentiated by DNA per basic genome, irrespective of polyploidy. The mean values of the two groups are 1.81 pg and 3.34 pg, respectively, showing a 1.84-fold difference. Within diploids and tetraploids there is 1.97-fold and 1.76-fold variation, respectively. 相似文献
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4C DNA values have been estimated in 16 cultivars ofCajanus cajan by cytophotometry. The values range between 6.19 pg to 7.97 pg, a 23.6% variation. The cultivars form four groups which differ significantly from each other but have insignificant difference within them. The implications of this variability with respect to the heterogeneity and origin of this legume crop are discussed. 相似文献
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Abstract: A very wide diversity of genome size and phenology has been shown in 75 Allium species belonging to all of the six subgenera. The 2C DNA amounts per genome, which range from 16.93 to 63.57 pg, do not show any significant negative correlation with flowering period or any direct relation with foliage leaf dormancy. This means that there is no general correlation between evolution of genome size and life strategies in the differentiation of the genus Allium. This conclusion is rather unexpected in being contrary to the ecological perspective of the nucleotype theory in the genus Allium. 相似文献
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Activation of the endoplasmic reticulum stress response (ERSR) is a hallmark of various pathological diseases and/or traumatic injuries. Restoration of ER homeostasis can contribute to improvement in the functional outcome of these diseases. Using genetic and pharmacological inhibition of the PERK-CHOP arm of the ERSR, we recently demonstrated improvements in hindlimb locomotion after spinal cord injury (SCI) and implicated oligodendrocyte survival as a potential mechanism. Here, we investigated the contribution of stress-inducible PPP1R15A/GADD34, an ERSR signaling effector downstream of CHOP that dephosphorylates eIF2α, in the pathogenesis of SCI. We show that although genetic ablation of GADD34 protects oligodendrocyte precursor cells (OPCs) against ER stress-mediated cell death in vitro and results in differential ERSR attenuation in vivo after SCI, there is no improvement in hindlimb locomotor function. Guanabenz, a FDA approved antihypertensive drug, was recently shown to reduce the burden of misfolded proteins in the ER by directly targeting GADD34. Guanabenz protected OPCs from ER stress-mediated cell death in vitro and attenuated the ERSR in vivo after SCI. However, guanabenz administration failed to rescue the locomotor deficits after SCI. These data suggest that deletion of GADD34 alone is not sufficient to improve functional recovery after SCI. 相似文献
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Hernan D. Gonorazky Sergey Naumenko Arun K. Ramani Viswateja Nelakuditi Pouria Mashouri Peiqui Wang Dennis Kao Krish Ohri Senthuri Viththiyapaskaran Mark A. Tarnopolsky Katherine D. Mathews Steven A. Moore Andres N. Osorio David Villanova Dwi U. Kemaladewi Ronald D. Cohn Michael Brudno James J. Dowling 《American journal of human genetics》2019,104(3):466-483
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Hernan D. Gonorazky Sergey Naumenko Arun K. Ramani Viswateja Nelakuditi Pouria Mashouri Peiqui Wang Dennis Kao Krish Ohri Senthuri Viththiyapaskaran Mark A. Tarnopolsky Katherine D. Mathews Steven A. Moore Andres N. Osorio David Villanova Dwi U. Kemaladewi Ronald D. Cohn Michael Brudno James J. Dowling 《American journal of human genetics》2019,104(5):1007
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Khanna Kanika Jamwal Vijay Lakshmi Kohli Sukhmeen Kaur Gandhi Sumit G. Ohri Puja Bhardwaj Renu Wijaya Leonard Alyemeni Mohammed Nasser Ahmad Parvaiz 《Plant and Soil》2019,439(1-2):325-338
Plant and Soil - As a major plant-derived soil organic carbon (SOC) component, lignin-derived phenolic compounds show varying biogeochemical characteristics compared to plant-derived lipid... 相似文献
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Ian PG Marshall Dusty RV Berggren Mohammad F Azizian Luke C Burow Lewis Semprini Alfred M Spormann 《The ISME journal》2012,6(4):814-826
We developed a broad-ranging method for identifying key hydrogen-producing and consuming microorganisms through analysis of hydrogenase gene content and expression in complex anaerobic microbial communities. The method is based on a tiling hydrogenase gene oligonucleotide DNA microarray (Hydrogenase Chip), which implements a high number of probes per gene by tiling probe sequences across genes of interest at 1.67 × –2 × coverage. This design favors the avoidance of false positive gene identification in samples of DNA or RNA extracted from complex microbial communities. We applied this technique to interrogate interspecies hydrogen transfer in complex communities in (i) lab-scale reductive dehalogenating microcosms enabling us to delineate key H2-consuming microorganisms, and (ii) hydrogen-generating microbial mats where we found evidence for significant H2 production by cyanobacteria. Independent quantitative PCR analysis on selected hydrogenase genes showed that this Hydrogenase Chip technique is semiquantitative. We also determined that as microbial community complexity increases, specificity must be traded for sensitivity in analyzing data from tiling DNA microarrays. 相似文献
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Modulation of c-myc and c-fos gene expression in regenerating rat liver by 2-mercaptopropionylglycine 总被引:6,自引:0,他引:6
Expression of the two proto-oncogenes, c- myc and c- fos, in proliferating liver, and the modulation of their expression by 2-mercaptopropionylglycine (MPG) has been investigated. A significant increase in the expression of both c-myc and c-fos was observed, attaining a peak at 30 min, followed by a gradual decline for 8h after partial hepatectomy. Treatment of partially hepatectomized animals with MPG resulted in a significant decrease in the expression of both genes, the decrease being more marked in c- myc mRNA levels. At later time points, there was a very small rise in the mRNA levels of these genes in MPG-treated animals but they still remained much lower than the peak levels observed in both genes 30 min after surgery. A decline in the recovery of liver weight in MPG-treated animals was also observed. 相似文献