全文获取类型
收费全文 | 625篇 |
免费 | 37篇 |
国内免费 | 2篇 |
出版年
2023年 | 7篇 |
2022年 | 6篇 |
2021年 | 22篇 |
2020年 | 9篇 |
2019年 | 15篇 |
2018年 | 13篇 |
2017年 | 12篇 |
2016年 | 22篇 |
2015年 | 26篇 |
2014年 | 33篇 |
2013年 | 45篇 |
2012年 | 44篇 |
2011年 | 44篇 |
2010年 | 31篇 |
2009年 | 27篇 |
2008年 | 31篇 |
2007年 | 30篇 |
2006年 | 23篇 |
2005年 | 27篇 |
2004年 | 19篇 |
2003年 | 17篇 |
2002年 | 14篇 |
2001年 | 11篇 |
2000年 | 11篇 |
1999年 | 9篇 |
1998年 | 5篇 |
1997年 | 6篇 |
1996年 | 3篇 |
1995年 | 3篇 |
1994年 | 6篇 |
1992年 | 7篇 |
1991年 | 7篇 |
1990年 | 7篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1986年 | 6篇 |
1985年 | 9篇 |
1984年 | 2篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1977年 | 7篇 |
1976年 | 2篇 |
1975年 | 3篇 |
1973年 | 3篇 |
1971年 | 4篇 |
1970年 | 4篇 |
1969年 | 2篇 |
1958年 | 2篇 |
排序方式: 共有664条查询结果,搜索用时 15 毫秒
661.
Prof. Ritchu Babbar Dr. Swikriti Makkar Dr. Deepika Saini Dr. Ravi Rawat Dr. Celia Vargas-De-La-Cruz Dr. Faris Q. Alenzi Prof. Tapan Behl 《化学与生物多样性》2023,20(8):e202300379
Designed, synthesized a sequence of novel benzimidazol-1-yl-1-phenylpropanone hybrids and assessed for in vitro antimicrobial potential counter to several bacterial strains. Computational Methodology was carried out for designing of the target molecules and structures were confirmed by spectroscopic analysis. Amid the 12 integrated derivatives, (3-(2-((3-fluorobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6g ) and 3-(2-((4-fluorobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6k ) were found to acquire excellent antibacterial activity against all bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus), whereas derivative 3-(2-((2-fluorobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6c ), was potent against Escherichia coli, Bacillus subtilis, Staphylococcus aureus and displayed moderate action against P. aeruginosa. Derivatives with NO2 substituent at 3rd and 4th position, 3-(2-((3-nitroobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6h ) and 3-(2-((4-nitroobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6 l ) respectively declared good to moderate results against all bacterial strains. Further, 3-(2-((3-chlorobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6f ) and 3-(2-((4-chlorobenzylidene)amino)-1H-benzo[d]imidazol-1-yl)-1-phenylpropan-1-one ( 6j ) were found to be more competent against both fungal strains (C. albicans, A. niger). Serial two-fold dilution method was used for the entire study and standard drugs utilized were ciprofloxacin and clotrimazole. MIC values (μg/ml) of novel synthesized analogs were reported in comparison to standard drugs for antibacterial and antifungal actions. Molecular docking studies showed that designed molecules dynamically bound with effective area of the receptor (DNA gyrase B, Clotrimazole complex of cytochrome P 45046A1) and in vitro results were in accord with in silico studies. 相似文献
662.
A simple, rapid and efficient procedure is presented for the purification of human prostatic acid phosphatase (orthophosphoric-monoester phosphohydrolase (acid optimum), EC 3.1.3.2) to homogeneity. The method employs two steps suitable for use with large quantities of material, followed by chromatography on concanavalin A-Sepharose as its sole column step. The procedure also permits the recovery of purified enzyme in higher yields than earlier methods. 相似文献
663.
R. P. Tiwari V. Mittal G. Singh T. C. Bhalla S. S. Saini D. V. Vadehra 《Folia microbiologica》1986,31(2):120-123
The effect of saturated and unsaturated fatty acids on aflatoxin production was studied in a synthetic medium. The aflatoxin production decreased (10-75%) in the presence of lauric acid and palmitic acid but the addition of behenic and sebacic acid stimulated aflatoxin production by 125-541%. Linolenic and linoleic acids effected aflatoxin production and mycelium growth. An 34-fold increase in aflatoxin production was observed with 50 mM linoleic acid. An inverse relationship was observed between aflatoxin production and mycelium mass, irrespective of the nature of the fatty acid. 相似文献
664.