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991.
Akinc A Zumbuehl A Goldberg M Leshchiner ES Busini V Hossain N Bacallado SA Nguyen DN Fuller J Alvarez R Borodovsky A Borland T Constien R de Fougerolles A Dorkin JR Narayanannair Jayaprakash K Jayaraman M John M Koteliansky V Manoharan M Nechev L Qin J Racie T Raitcheva D Rajeev KG Sah DW Soutschek J Toudjarska I Vornlocher HP Zimmermann TS Langer R Anderson DG 《Nature biotechnology》2008,26(5):561-569
992.
So far the vast majority of studies on large carnivore predation, including kill rates and consumption, have been based on
winter studies. Because large carnivores relying on ungulates as prey often show a preference for juveniles, kill rates may
be both higher and more variable during the summer season than during the rest of the year leading to serious underestimates
of the total annual predation rate. This study is the first to present detailed empirical data on kill rates and prey selection
in a wolf–moose system during summer (June–September) as obtained by applying modern Global Positioning System-collar techniques
on individual wolves (Canis lupus) in Scandinavia. Moose (Alces alces) was the dominant prey species both by number (74.4%) and biomass (95.6%); 89.9% of all moose killed were juveniles, representing
76.0% of the biomass consumed by wolves. Kill rate in terms of the kilogram biomass/kilogram wolf per day averaged 0.20 (range:
0.07–0.32) among wolf territories and was above, or well above, the daily minimum food requirements in most territories. The
average number of days between moose kills across wolf territories and study periods was 1.71 days, but increased with time
and size of growing moose calves during summer. Over the entire summer (June–September, 122 days), a group (from two to nine)
of wolves killed a total of 66 (confidence interval 95%; 56–81) moose. Incorporation of body growth functions of moose calves
and yearlings and wolf pups over the summer period showed that wolves adjusted their kill rate on moose, so the amount of
biomass/kilogram wolf was relatively constant or increased. The kill rate was much higher (94–116%) than estimated from the
winter period. As a consequence, projecting winter kill rates to obtain annual estimates of predation in similar predator–prey
systems may result in a significant underestimation of the total number of prey killed.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
993.
Emotional contagion enables individuals to experience emotions of others. This important empathic phenomenon is closely linked to facial mimicry, where facial displays evoke the same facial expressions in social partners. In humans, facial mimicry can be voluntary or involuntary, whereby its latter mode can be processed as rapid as within or at 1s. Thus far, studies have not provided evidence of rapid involuntary facial mimicry in animals.This study assessed whether rapid involuntary facial mimicry is present in orangutans (Pongo pygmaeus; N=25) for their open-mouth faces (OMFs) during everyday dyadic play. Results clearly indicated that orangutans rapidly mimicked OMFs of their playmates within or at 1s. Our study revealed the first evidence on rapid involuntary facial mimicry in non-human mammals. This finding suggests that fundamental building blocks of positive emotional contagion and empathy that link to rapid involuntary facial mimicry in humans have homologues in non-human primates. 相似文献
994.
995.
Uncovering the Fate of Critical Metals: Tracking Dissipative Losses along the Product Life Cycle 下载免费PDF全文
Till Zimmermann 《Journal of Industrial Ecology》2017,21(5):1198-1211
An increasing number of elements from the periodic table are being used in a growing number of products, enabling new material and product functionalities. Materials of high importance and high supply risks are usually referred to as critical materials. Many materials that are often considered critical are used in ways leading to their dissipative loss along the product life cycle. So far, the issue of material dissipation has been dealt with mainly on a rather aggregated level. Detailed knowledge on the occurrence and amount of dissipative losses in the life cycle of specific products is only scarcely available. Addressing this, a substance flow analysis of different critical metals along the life cycle of selected products is presented in this article. With regard to products used in Germany, the flows of indium and gallium used in copper‐indium‐gallium‐selenide (CIGS) photovoltaic cells, germanium used in polymerization catalysts, and yttrium used in thermal barrier coatings (TBCs) have been analyzed. The results comprise detailed knowledge about the life cycle stages in which dissipative losses occur and about the receiving media. In all case studies, a complete or almost complete dissipative loss can be observed, mainly to landfills and other material flows. In all case studies, material production can be identified as hotspots for dissipative losses. In two case studies fabrication and manufacturing (F&M for CIGS and TBCs) and in one case study end of life (polymerization catalysts) can be identified as further hotspots for dissipative losses. In addition, actions for reducing dissipation along the life cycle are discussed, targeting aspects such as the recovery of critical metals as by‐products, efficiency in F&M processes, and lack of recycling processes. Lack of economic incentives to apply more‐efficient technologies and processes already available is a key aspect in this regard. 相似文献
996.
Laure Gallien Niklaus E. Zimmermann Jonathan M. Levine Peter B. Adler 《Ecology letters》2017,20(7):791-800
Coexistence theory has been developed with an almost exclusive focus on interactions between two species, often ignoring more complex and indirect interactions, such as intransitive loops, that can emerge in competition networks. In fact, intransitive competition has typically been studied in isolation from other pairwise stabilising processes, and thus little is known about how intransitivity interacts with more traditional drivers of species coexistence such as niche partitioning. To integrate intransitivity into traditional coexistence theory, we developed a metric of growth rate when rare, , to identify and quantify the impact of intransitive competition against a backdrop of pairwise stabilising niche differences. Using this index with simulations of community dynamics, we demonstrate that intransitive loops can both stabilise or destabilise species coexistence, but the strength and importance of intransitive interactions are significantly affected by the length and the topology of these loops. We conclude by showing how can be used to evaluate effects of intransitivity in empirical studies. Our results emphasise the need to integrate complex mechanisms emerging from diverse interactions into our understanding of species coexistence. 相似文献
997.
Indirect IL-4 pathway in type 1 immunity. 总被引:4,自引:0,他引:4
Alexey Y Karulin Maike D Hesse Hualin C Yip Paul V Lehmann 《Journal of immunology (Baltimore, Md. : 1950)》2002,168(2):545-553
Recall Ag-specific IL-4 was detected in the spleen and in the blood, but not in lymph nodes of mice in which polarized type 1 immunity was induced. This IL-4 was not produced by T cells, but soluble factors secreted by the recall Ag-activated T cells, including IL-3, triggered cells of the innate immune system, primarily mast cells, to secrete IL-4. This notion has profound implications for immunodiagnostics: the detection of apparently recall Ag-specific IL-4 does not necessarily reflect the presence of Th2 or Th0 memory T cells with long-term cytokine commitment as is of interest for assessing adoptive immunity. We found that in vivo the indirect IL-4 pathway did not suffice to trigger IgE isotype switching, but promoted IgG1 production and inhibited type 1 T cell differentiation. Therefore, the indirect IL-4 pathway can explain partial type 2 immune response phenotypes in vivo in face of unipolar Th1 T cell immunity. The representation of mast cells in different tissues may explain why immune responses in certain organs are more type 2 biased. Therefore, the indirect pathway of IL-4 production represents a novel type of interaction between the innate and the adoptive immune system that can contribute to the outcome of host defense and immune pathology. 相似文献
998.
999.
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. 总被引:27,自引:0,他引:27
Guenter Haemmerle Robert Zimmermann Marianne Hayn Christian Theussl Georg Waeg Elke Wagner Wolfgang Sattler Thomas M Magin Erwin F Wagner Rudolf Zechner 《The Journal of biological chemistry》2002,277(7):4806-4815
Hormone-sensitive lipase (HSL) is expressed predominantly in white and brown adipose tissue where it is believed to play a crucial role in the lipolysis of stored triglycerides (TG), thereby providing the body with energy substrate in the form of free fatty acids (FFA). From in vitro assays, HSL is known to hydrolyze TG, diglycerides (DG), cholesteryl esters, and retinyl esters. In the current study we have generated HSL knock-out mice and demonstrate three lines of evidence that HSL is instrumental in the catabolism of DG in vivo. First, HSL deficiency in mice causes the accumulation of DG in white adipose tissue, brown adipose tissue, skeletal muscle, cardiac muscle, and testis. Second, when tissue extracts were used in an in vitro lipase assay, a reduced FFA release and the accumulation of DG was observed in HSL knock-out mice which did not occur when tissue extracts from control mice were used. Third, in vitro lipolysis experiments with HSL-deficient fat pads demonstrated that the isoproterenol-stimulated release of FFA was decreased and DG accumulated intracellularly resulting in the essential absence of the isoproterenol-stimulated glycerol formation typically observed in control fat pads. Additionally, the absence of HSL in white adipose tissue caused a shift of the fatty acid composition of the TG moiety toward increased long chain fatty acids implying a substrate specificity of the enzyme in vivo. From these in vivo results we conclude that HSL is the rate-limiting enzyme for the cellular catabolism of DG in adipose tissue and muscle. 相似文献
1000.
Wood-ash recycling affects forest soil and tree fine-root chemistry and reverses soil acidification 总被引:1,自引:1,他引:0
Wood ash was applied to a forest ecosystem with the aim to recycle nutrients taken from the forest and to mitigate the negative
effects of intensive harvesting. After two years, the application of 8,000 kg ha−1 of wood ash increased soil exchangeable Ca and Mg. Similarly, an increase in Ca and Mg in the Norway spruce fine roots was
recorded, leading to significant linear correlations between soil and root Ca and soil and root Mg. In contrast to these macronutrients,
the micronutrients Fe and Zn and the toxic element Al decreased in the soil exchangeable fraction with the addition of wood
ash, but not in the fine roots. Only Mn decreased in soil and in fine roots leading to a significant linear correlation between
soil and root Mn. In soil, as well as in fine roots, strong positive correlations were found between the elements Ca and Mg
and between Fe and Al. This indicates that the uptake of Mg resembles that of Ca and that of Al that of Fe. With the wood
ash application, the pH increased from 3.2 to 4.8, the base saturation from 30% to 86%, the molar basic cations/Al ratio (BC/Al)
of the soil solution from 1.5 to 5.5, and the molar Ca/Al ratio of the fine roots from 1.3 to 3.7. Overall, all below-ground
indicators of soil acidification responded positively to the wood ash application within two years. Nitrate concentrations
increased only slightly in the soil solution at a soil depth of 75–80 cm, and no signs of increased heavy metal concentrations
in the soils or in the fine roots were apparent. This suggests that the recycling of wood ash could be an integral part of
sustainable forest management because it closes the nutrient cycle and reverses soil acidification. 相似文献