Rpn4p without the DNA-Binding Domain Provides Saccharomyces cerevisiae Resistance to Oxidative Stress and Cycloheximide

Molecular Biology - The ubiquitin-proteasome system is involved in the control of all essential molecular processes under normal conditions and the response of cells to stress. Rpn4p serves as a...     

Results of the clusterization of human microtubule and cell-cycle related serine/threonine protein kinases and their plant homologues

We identified 191 plant homologues of human protein kinases involved in the phosphorylation of microtubular proteins and cell-cycle regulation. Using neighbor-joining, the similarity of plant protein kinases was analyzed.     

Interaction of SiFe Nanoparticles with Epithelial and Lymphoid Cells

Russian Journal of Bioorganic Chemistry - Silicon and silicon-based nanoparticles (SiNP) attract scientific attention due to the biocompatibility and assimilation of silicon by body tissues....     

The effect of oxidized cholesterol derivatives on the absorption and degradation of very low density beta-lipoproteins by human and rabbit hepatocytes

In our study the influence of oxidated cholesterol derivatives (7 alpha, 7 beta-oxicholesterol, 7-ketocholesterol, cholestene-3-one) on binding and degradation of beta-VLDL by human and rabbit hepatocytes was investigated. Cholesterol oxy derivatives inhibit the degradation of beta-VLDL in rabbit hepatocyte culture. There is no such effect with human hepatocytes. However beta-VLDL binding with human hepatocytes is significantly decreased under oxidated cholesterol derivatives influence.     

The adhesive properties of meningococci from serogroups A, B and C

The adhesive properties of 261 meningococcal strains have been studied by the methods of the hemagglutination test, the test of adhesion on buccal epithelial cells and electron microscopy. The study has revealed that adhesive properties can be observed in the strains of all groups under study (A, B and C) isolated from patients and carriers, including those isolated from the nasopharynx, blood and liquor, adhesive properties occurring in newly isolated strains with greater frequency than in museum ones. The simultaneous use of all three above-mentioned methods increases the possibility of the detection of meningococcal strains with adhesive activity.