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641.
Janis Crandlemire-Sacco 《Primates; journal of primatology》1988,29(4):465-475
The ecologies of two sympatric primates,Saguinus fuscicollis andCallicebus moloch, were compared during a four-month field study in southeastern Peru in order to examine the mechanisms by which these primate
frugivores minimize competition for food and space.Saguinus fuscicollis andCallicebus moloch were found to differ dramatically both in diet and in use of the shared habitat. Specifically, tamarins and titis showed
very little overlap in their choices of food plants or animal foods and they used distinctive foraging styles, exploiting
very different parts of the habitat for animal prey. Significant interspecific differences were found in the use of particular
support structures and strata within the forest, and in the density of vegetation preferred. These results suggest that resource
competition between saddle-backed tamarins and dusky titis is minimal, a fact that could account for the high frequency of
free association between the two species and the benign nature of these interspecific contacts. 相似文献
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643.
Janis S. Fisler Craig H. Warden Mario J. Pace Aldons J. Lusis 《Obesity (Silver Spring, Md.)》1993,1(4):271-280
We report here a new mouse model of multigenic obesity. Backcross progeny ((C57BL/6J x Mus spretus)F1 x C57BL/6J), designated as BSB mice, range from 1% to 50% body fat. Since both parental strains are relatively lean, the wide range of the phenotype in the BSB mice indicates the involvement of multiple genes to produce obesity. Obesity in BSB mice results from increases in both intraabdominal and subcutaneous fat and is associated with hyperinsulinemia, hyperglycemia, and hyperlipidemia. Female and male BSB mice do not differ in the degree of obesity obtained. Stimulated plasma corticosterone levels are reduced in obese male and female mice. The development of appropriate genetic markers and statistical methods have made it feasible to analyze quantitative polygenic traits in animal models by employing F2 or backcross progeny. Thus, this BSB model is uniquely suited to the genetic analysis of the multifactorial quantitative trait of obesity and its associated phenotypes. (OBESITY RESEARCH 1993;1:271–280) 相似文献
644.
R.A. Janis B.M. Moats-Staats R.T. Gualtieri 《Biochemical and biophysical research communications》1980,96(1):265-270
The relationship between spontaneous contraction and protein phosphorylation of rat uterine smooth muscle was studied. Myometrial strips from estrogen-dominated rats were incubated in [32P]orthophosphate and then frozen at various levels of isometric tension. Proteins were separated by gel electrophoresis and the incorporation of 32P was measured. Contraction was associated with the phosphorylation of one major protein (20,000 Mr). This phosphorylation preceded maximal tension development and dephosphorylation preceded complete spontaneous relaxation. Two-dimensional gel electrophoresis indicates that the 20,000-Mr protein is the myosin light chain which has been implicated in the regulation of smooth muscle contraction. 相似文献
645.
Eilis Hannon Georgina Mansell Emma Walker Marta F. Nabais Joe Burrage Agnieszka Kepa Janis Best-Lane Anna Rose Suzanne Heck Terrie E. Moffitt Avshalom Caspi Louise Arseneault Jonathan Mill 《PLoS genetics》2021,17(3)
Most epigenome-wide association studies (EWAS) quantify DNA methylation (DNAm) in peripheral tissues such as whole blood to identify positions in the genome where variation is statistically associated with a trait or exposure. As whole blood comprises a mix of cell types, it is unclear whether trait-associated DNAm variation is specific to an individual cellular population. We collected three peripheral tissues (whole blood, buccal epithelial and nasal epithelial cells) from thirty individuals. Whole blood samples were subsequently processed using fluorescence-activated cell sorting (FACS) to purify five constituent cell-types (monocytes, granulocytes, CD4+ T cells, CD8+ T cells, and B cells). DNAm was profiled in all eight sample-types from each individual using the Illumina EPIC array. We identified significant differences in both the level and variability of DNAm between different sample types, and DNAm data-derived estimates of age and smoking were found to differ dramatically across sample types from the same individual. We found that for the majority of loci variation in DNAm in individual blood cell types was only weakly predictive of variance in DNAm measured in whole blood, although the proportion of variance explained was greater than that explained by either buccal or nasal epithelial samples. Covariation across sample types was much higher for DNAm sites influenced by genetic factors. Overall, we observe that DNAm variation in whole blood is additively influenced by a combination of the major blood cell types. For a subset of sites, however, variable DNAm detected in whole blood can be attributed to variation in a single blood cell type providing potential mechanistic insight about EWAS findings. Our results suggest that associations between whole blood DNAm and traits or exposures reflect differences in multiple cell types and our data will facilitate the interpretation of findings in epigenetic epidemiology. 相似文献
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647.
Some properties of a newly isolated Haemophilus influenzae bacteriophage are described. The phage is morphologically distinct from previously described H. influenzae phages. 相似文献
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649.
Huastec noncrop resource management: Implications for prehistoric rain forest management 总被引:1,自引:0,他引:1
Janis B. Alcorn 《Human ecology: an interdisciplinary journal》1981,9(4):395-417
The Huastec have interacted with elements of a diverse flora in northeastern Mexico for 30 centuries. A Huastec plant-management model is derived from patterns reflected in all anthropogenic vegetation zones, from the dooryard to the forest, and used to discuss the possible effects of human activities upon the prehistoric rain forest. Huastec plant management is discussed from an analytical perspective which views plant management as resulting from the integration of two types of plant manipulation: the manipulation of vegetation en masse and the manipulation of individual plants. Decisions about plant manipulation reflect a concern for minimal labor investment to place the resource at hand. Noncrop plant manipulation practices potentially influence the evolution of individual plants and plant communities primarily by affecting species' distribution and population parameters. Since the impact of plant-management practices clearly goes beyond domestication, ways of evaluating such practices in order to expand our understanding of ethnobotanical interactions and their impact are suggested. 相似文献