全文获取类型
收费全文 | 606篇 |
免费 | 41篇 |
国内免费 | 3篇 |
出版年
2024年 | 1篇 |
2023年 | 16篇 |
2022年 | 21篇 |
2021年 | 65篇 |
2020年 | 35篇 |
2019年 | 31篇 |
2018年 | 46篇 |
2017年 | 37篇 |
2016年 | 31篇 |
2015年 | 39篇 |
2014年 | 30篇 |
2013年 | 46篇 |
2012年 | 41篇 |
2011年 | 29篇 |
2010年 | 8篇 |
2009年 | 17篇 |
2008年 | 15篇 |
2007年 | 13篇 |
2006年 | 21篇 |
2005年 | 12篇 |
2004年 | 8篇 |
2003年 | 8篇 |
2002年 | 4篇 |
2001年 | 5篇 |
2000年 | 9篇 |
1999年 | 1篇 |
1998年 | 4篇 |
1997年 | 2篇 |
1995年 | 5篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1991年 | 4篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 14篇 |
1987年 | 5篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1973年 | 1篇 |
1969年 | 1篇 |
1967年 | 1篇 |
1965年 | 1篇 |
1961年 | 1篇 |
排序方式: 共有650条查询结果,搜索用时 421 毫秒
641.
Asim Raza Dr. Mohsin Abbas Khan Prof. Dr. Irshad Ahmad Dr. Sajid Ur Rehman Dr. Saharish Khaliq Dr. Javed Ahmed Breena Awan Farhat Ullah Anum Masood Naveed Ahmed 《化学与生物多样性》2023,20(7):e202300482
Prodrugs of dexibuprofen having ester moieties instead of free carboxylic acid which involves in gastrointestinal side effects have been synthesized. Dexibuprofen acid was condensed with different alcohols/phenols to afford the ester prodrugs. All of the synthesized prodrugs were characterized by their physical attributes, elemental analysis, FT-IR, 1H-NMR, and 13C-NMR spectroscopy. The in vitro anti-inflammatory studies was done by chemiluminescence technique reflect prodrugs have been more potent, owing to the different chemical structures. Lipoxygenase enzyme inhibition assay was also assess and found compound DR7 with IC50=19.8 μM), DR9 (IC50=24.8 μM) and DR3 (IC50=47.2 μM) as compared with Dexibuprofen (IC50=156.6 μM). It was also evaluated for docking studies revealed that DR7 has found to be more potent anti-inflammatory against 5-LOX (3 V99) as well as analgesic against COX-II (5KIR) enzyme. Anti-oxidant activities were also performed, DR3 (86.9 %), DR5 (83.5 %), DR7 (93.9 %) and DR9 (87.4 %) were found to be more anti-oxidant as compared to (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid (52.7 %). 相似文献
642.
Natural variation in Tiller Number 1 affects its interaction with TIF1 to regulate tillering in rice
Quan Zhang Jianyin Xie Xiaoyang Zhu Xiaoqian Ma Tao Yang Najeeb Ullah Khan Shuyang Zhang Miaosong Liu Lin Li Yuntao Liang Yinghua Pan Danting Li Jinjie Li Zichao Li Hongliang Zhang Zhanying Zhang 《Plant biotechnology journal》2023,21(5):1044-1057
Tiller number per plant—a cardinal component of ideal plant architecture—affects grain yield potential. Thus, alleles positively affecting tillering must be mined to promote genetic improvement. Here, we report a Tiller Number 1 (TN1) protein harbouring a bromo-adjacent homology domain and RNA recognition motifs, identified through genome-wide association study of tiller numbers. Natural variation in TN1 affects its interaction with TIF1 (TN1 interaction factor 1) to affect DWARF14 expression and negatively regulate tiller number in rice. Further analysis of variations in TN1 among indica genotypes according to geographical distribution revealed that low-tillering varieties with TN1-hapL are concentrated in Southeast Asia and East Asia, whereas high-tillering varieties with TN1-hapH are concentrated in South Asia. Taken together, these results indicate that TN1 is a tillering regulatory factor whose alleles present apparent preferential utilization across geographical regions. Our findings advance the molecular understanding of tiller development. 相似文献
643.
Ali Hafiz Muhammad Mubashar Perveen Shagufta 《Physiology and Molecular Biology of Plants》2020,26(6):1215-1224
Physiology and Molecular Biology of Plants - In this study, changes in growth, yield and photosynthetic characteristics were assessed by foliar application of triacontanol (TRIA) in wheat (Triticum... 相似文献
644.
645.
Rahim Muhamad Hafiz Abd Hasan Hanan Harith Hanis H. Abbas Ali 《Bioprocess and biosystems engineering》2017,40(12):1753-1761
Bioprocess and Biosystems Engineering - This study investigates the effects of viscosity, friction, and sonication on the morphology and the production of lovastatin, (+)-geodin, and sulochrin by... 相似文献
646.
Toshihiko Arai Takao Ando Atsuko Kusakabe Md. Arshad Ullah 《Microbiology and immunology》1983,27(12):1021-1029
We surveyed plasmids in naturally occurring Vibrio parahemolyticus strains isolated in Japan and Bangladesh. Among the strains isolated in Japan, about half of the strains isolated from stools of patients of domestic diarrhea outbreaks as well as of travelers returning from East Asia were found to have plasmids, but no strains from foods had plasmids. In contrast, among the strains isolated in Bangladesh, none of the four strains isolated from patients had plasmids, but two out of eight strains isolated from water had plasmids, suggesting that plasmids are common in strains from the water in Bangladesh. All plasmids so far reported in V. parahemolyticus were detected in strains isolated from stools of patients. Incidences of plasmids in this organism were not so high in either area. In Japan, all plasmids were detected in strains from human intestines at 37 C, but in Bangladesh, where the temperature is around 30–40 C, the plasmids were detected in strains from the natural environment. These results suggested the possibility that these plasmids can come from different bacteria under rather high temperatures and that incidences of plasmids are influenced by the incidences of plasmids in bacteria present in the vicinity of V. parahemolyticus strains. None of these plasmids were found to have any relation to the biological characters tested. 相似文献
647.
In this paper we applied a new analytic approximate technique Optimal Homotopy Asymptotic Method (OHAM) for treatment of coupled differential- difference equations (DDEs). To see the efficiency and reliability of the method, we consider Relativistic Toda coupled nonlinear differential-difference equation. It provides us a convenient way to control the convergence of approximate solutions when it is compared with other methods of solution found in the literature. The obtained solutions show that OHAM is effective, simpler, easier and explicit. 相似文献
648.
Journal of Plant Growth Regulation - Balanced nutrition is imperative for efficient nutrient management and has a considerable role in enhancing crop yield. To study the effect of various nitrogen... 相似文献
649.
Shah Muqader Zaneb Hafsa Masood Saima Khan Rifat Ullah Ashraf Saima Sikandar Arbab Rehman Hafiz Faseeh Ur Rehman Habib Ur 《Probiotics and antimicrobial proteins》2019,11(3):931-937
Probiotics and Antimicrobial Proteins - This experiment aimed to investigate the effect of different levels of zinc (Zn) and a probiotic on the growth and intestinal health of broiler chickens. One... 相似文献
650.
Extracellular alpha galactosidase (E.C. 3.2.1.22) from Aspergillus ficuum NRRL 3135 purification and characterization 总被引:3,自引:0,他引:3
Extracellular alpha-galactosidase, a glycoprotein from the extracellular culture fluid of Aspergillus ficuum grown on glucose and raffinose in a batch culture system, was purified to homogeneity in five steps by ion exchange and hydrophobic interaction chromatography. The molecular mass of the enzyme was 70.8 Kd by SDS polyacrylamide gel electrophoresis and 74.1 Kd by gel permeation HPLC. On the basis of a molecular mass of 70.7 Kd, the molar extinction coefficient of the enzyme at 279 nm was estimated to be 6.1 X10(4) M-1 cm-1. The purified enzyme was remarkably stable at 0 degrees C. It had a broad temperature optimum and maximum catalytic activity was at 60 degrees C. It retained 33% of its activity after 10 min. at 65 degrees C. It had a pH optimum of 6.0. It retained 62% of its activity after 12 hours at pH 2.3. The Kms for p-nitrophenyl-alpha-D-galactopyranoside, o-nitrophenyl-alpha-D-galactopyranoside and m-nitrophenyl-alpha-D-galactopyranoside are: 1462, 839 and 718 microM. The enzyme was competitively inhibited by mercury (19.8 microM), silver (21.5 microM), copper (0.48 mM), zinc (0.11 mM), galactose (64.0 mM) and fructose (60.3 mM). It was inhibited non-competitively by glucose (83.2 mM) and uncompetitively by mannose (6.7 mM). 相似文献