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T Ceddia M C Marinucci N Parravano 《Bollettino della Società italiana di biologia sperimentale》1979,55(6):529-533
The AA report about the resistence towards antibiotics of 42 stocks of Pseudomonas aeruginosa isolated from hospitalized patients and of 18 stocks isolated from non hospitalized patients. The most active antibiotics are Gentamicine, Neomicine and Streptomicine. Interestingly towards Tobramicine no resistence has been detected. The stocks isolated from hospitalized patients have generally shown a higher resistence. 相似文献
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P. M. Guyre Robert F. Graziano Joel Goldstein Paul K. Wallace Peter M. Morganelli Kathleen Wardwell Alexandra L. Howell 《Cancer immunology, immunotherapy : CII》1997,45(3-4):146-148
A major challenge for using native and modified T cell epitopes to induce or suppress immunity relates to achieving efficient
uptake and processing by antigen-presenting cells (APC) in vivo. IgG Fc receptors, which are expressed constitutively by professional
APC including monocytes and dendritic cells, have long been known to mediate antigen uptake in a manner leading to efficient
T cell activation. We have previously demonstrated enhanced presentation of antigenic and antagonistic peptides by targeting
them to the type I Fc receptor for IgG (FcγRI, CD64) on human monocytes. In the present report we review the literature suggesting
that CD64-targeted antigens are likely to be effective in vivo, and present data demonstrating enhanced immunogenicity in
CD64 transgenic mice of a fusion protein that combines the specificities of HIV gp120 and the humanized anti-CD64 monoclonal
antibody H22. Overall, these studies suggest that targeting antigens to CD64 represents an effective approach to enhancing
the effectiveness of vaccines in vivo.
Accepted: 14 October 1997 相似文献
526.
Isabella Barajon Graziano Serrao Francesca Arnaboldi Emanuela Opizzi Gerlomina Ripamonti Andrea Balsari Cristiano Rumio 《The journal of histochemistry and cytochemistry》2009,57(11):1013-1023
The aim of the present study was to evaluate the expression of innate immunity receptors belonging to the Toll-like family in the neural plexuses of the different tracts of murine intestine, of the human ileum, and in lower dorsal root ganglia (DRGs) from where extrinsic afferents to these plexuses originate. Results obtained by immunohistochemistry and immunofluorescence on paraffin-embedded tissue and whole-mount preparations show that Toll-like receptors (TLRs) -3 and -7, recognizing viral RNA, and TLR4, recognizing lipopolysaccharide (membrane component of Gram-negative bacteria), are expressed in the myenteric and submucous plexuses of murine intestine and human ileum, and in DRGs primary sensory neurons. They also show that TLR4 immunostaining is stronger in murine distal large bowel. In murine tissue, expression of TLRs was present in both neurons and glial cells. These observations indicate that the enteric neural network might be directly activated by bacterial and viral components and is therefore more in the forefront than previously envisaged in defense responses of the intestinal wall and in the cross-talk with intestinal microbiota. They also highlight the presence of a peripheral neural network that by way of hardwired neurotransmission could potentially convey to the central nervous system specific information on our microbial counterpart and invading or potentially invading pathogens. (J Histochem Cytochem 57:1013–1023, 2009) 相似文献
527.
Lacking an external shell and a rigid endoskeleton, octopuses exhibit a remarkable flexibility in their movements. Bipedal locomotion is perhaps the most iconic example in this regard. Until recently, this peculiar mode of locomotion had been observed only in two species of tropical octopuses: Amphioctopus marginatus and Abdopus aculeatus. Yet, recent evidence indicates that bipedal walking is also part of the behavioral repertoire of the common octopus, Octopus vulgaris. Here we report a further observation of a defense behavior that encompasses both postural and locomotory elements of bipedal locomotion in this cephalopod. By highlighting differences and similarities with the other recently published report, we provide preliminary considerations with regard to bipedal locomotion in the common octopus. 相似文献
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T Ceddia R Cialfi A Mancini M C Marinucci 《Bollettino della Società italiana di biologia sperimentale》1979,55(6):538-543
Among the large O-groups of E.coli isolated from urinary-tract infections, a few groups appear more frequent. The AA report about this frequency in the district of L'Aquilla. Of 147 stocks of E.coli, the most frequent O-groups are the O6 (28,5%), the O75 (20,4%), the O2 (10,2%), the O18 (6,1%), the O5 (4,1%), the O39 (2%). 相似文献