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排序方式: 共有597条查询结果,搜索用时 187 毫秒
91.
France Lelong 《Mathematical biosciences》1982,59(1):145-155
In a global pulmonary gas exchange model where global diffusion and ventilation are given, the effects of variations of local conductance?perfusion and ventilation?perfusion ratios on O2 concentration in arterial blood are studied. We give a special regard to the ability to get local maxima for this O2 concentration when the repartition of our parameters is heterogeneous. 相似文献
92.
Aurélien Sokal Pascal Chappert Giovanna Barba-Spaeth Anais Roeser Slim Fourati Imane Azzaoui Alexis Vandenberghe Ignacio Fernandez Annalisa Meola Magali Bouvier-Alias Etienne Crickx Asma Beldi-Ferchiou Sophie Hue Laetitia Languille Marc Michel Samia Baloul France Noizat-Pirenne Marine Luka Matthieu Mahévas 《Cell》2021,184(5):1201-1213.e14
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Robert L. France 《Hydrobiologia》1993,271(2):71-74
Hyalella azteca (Amphipoda) were sampled in eight Canadian Shield lakes, and the inter-relationships among life history traits were used
to determine the sensitivity of production and turnover rates to demographic variation. Production was positively related
to density and negatively related to both mortality and somatic growth. Turnover rates did not vary significantly with respect
to any demographic traits. Studies should advance from simply documenting production to instead describing ‘production ecology’
if an understanding of the environmental determinance of population regulation is desired. 相似文献
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Pascale Mentré 《Journal of biological physics》2012,38(1):13-26
Nowadays, biologists can explore the cell at the nanometre level. They discover an unsuspected world, amazingly overcrowded,
complex and heterogeneous, in which water, also, is complex and heterogeneous. In the cell, statistical phenomena, such as
diffusion, long considered as the main transport for water soluble substances, must be henceforth considered as inoperative
to orchestrate cell activity. Results at this level are not yet numerous enough to give an exact representation of the cell
machinery; however, they are sufficient to cease reasoning in terms of statistics (diffusion, law of mass action, pH, etc.) and encourage cytologists and biochemists to prospect
thoroughly the huge panoply of the biophysical properties of macromolecule-water associations at the nanometre level. Our
main purpose, here, is to discuss some of the more common misinterpretations due to the ignorance of these properties, and
expose briefly the bases for a better approach of the cell machinery. Giorgio Careri, who demonstrated the correlation between
proton currents at the surface of lysozyme and activity of this enzyme was one of the pioneers of this approach. 相似文献
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Hydrogen peroxide production and myo‐inositol metabolism as important traits for virulence of Mycoplasma hyopneumoniae 下载免费PDF全文
Delphine Parrot Guillaume Meiffrein Jose Fernando Ruggiero Bachega Gilles Comte Arnaldo Zaha Marie‐France Sagot 《Molecular microbiology》2018,108(6):683-696
Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia. In our previous work, we reconstructed the metabolic models of this species along with two other mycoplasmas from the respiratory tract of swine: Mycoplasma hyorhinis, considered less pathogenic but which nonetheless causes disease and Mycoplasma flocculare, a commensal bacterium. We identified metabolic differences that partially explained their different levels of pathogenicity. One important trait was the production of hydrogen peroxide from the glycerol metabolism only in the pathogenic species. Another important feature was a pathway for the metabolism of myo‐inositol in M. hyopneumoniae. Here, we tested these traits to understand their relation to the different levels of pathogenicity, comparing not only the species but also pathogenic and attenuated strains of M. hyopneumoniae. Regarding the myo‐inositol metabolism, we show that only M. hyopneumoniae assimilated this carbohydrate and remained viable when myo‐inositol was the primary energy source. Strikingly, only the two pathogenic strains of M. hyopneumoniae produced hydrogen peroxide in complex medium. We also show that this production was dependent on the presence of glycerol. Although further functional tests are needed, we present in this work two interesting metabolic traits of M. hyopneumoniae that might be directly related to its enhanced virulence. 相似文献