General mean‐field theory for mechanical hysteresis of network‐like macromolecules

In the framework of the mean‐field theory for the order parameter, which characterizes the degree of deviating the structure of a network‐like macromolecule from its natural state under the action of the external force, its mechanical hysteresis is considered. Elastic hysterical properties of a macromolecule are studied as a function of the applied force, temperature and some other parameters controlling the viscous‐elastic behavior of network‐like macromolecules. Proteins 2014; 82:3188–3193. © 2014 Wiley Periodicals, Inc.     

Repeated sequences with unusual properties from the divergent region of Crithidia oncopelti maxicircle kinetoplast DNA

Summary The occurrence of bacterial promoter-like sequences was shown in the divergent region ofCrithidia oncopelti maxicircular kinetoplast DNA. A promoter-cloning vector based on the neomycin phosphotransferase II (NPT II) gene was used to localize promoters in three homologous blocks of repeated sequences. The elements found displayed greater promoter strength inEscherichia coli than the normal promoter of the NPT II gene. Sequences of three promoter-containing inserts from different blocks were determined and typical prokaryotic promoter sequences were localized.     

Synthesis of N-substituted morpholine nucleoside derivatives

Abstract

Herein, we report the synthesis of substituted morpholino nucleoside derivatives starting from ribonucleosides. The present protocol shows high functional group tolerance, uses mild reaction conditions, and gives moderate to good yields. This transformation is based on two sequential pathways: (i) the oxidation of the ribonucleosides to the corresponding dialdehyde using sodium periodate and (ii) the reductive amination of the in situ generated dialdehydes with the hydrochloride salts of various the alkylamines.     

Rapid miniaturization of Salvelinus fish as an adaptation to the volcanic impact

Hydrobiologia - Volcanoes serve as natural laboratories expanding our understanding of the recent and past ecological and evolutionary processes. Here, we present data elucidating the developmental...