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101.
Funck Graciele Daiana de Lima Marques Juliana da Silva Dannenberg Guilherme dos Santos Cruxen Claudio Eduardo Sehn Carla Pohl Prigol Marina Silva Márcia Rósula Poetini da Silva Wladimir Padilha Fiorentini Ângela Maria 《Probiotics and antimicrobial proteins》2020,12(1):91-101
Probiotics and Antimicrobial Proteins - This study aimed to characterize, evaluate toxicity and optimize the conditions for the growth and production of bacteriocin-like substances by Lactobacillus... 相似文献
102.
Ailec Ho‐Plagaro Concepcin Santiago‐Fernandez Cristina Rodríguez‐Díaz Carlos Lopez‐Gmez Sara Garcia‐Serrano Francisca Rodríguez‐Pacheco Sergio Valdes Alberto Rodríguez‐Caete Guillermo Alcaín‐Martínez Natalia Ruiz‐Santana Luis Vzquez‐Pedreo Eduardo García‐Fuentes 《Obesity (Silver Spring, Md.)》2020,28(9):1708-1717
103.
Cesar B. Ramírez-López Rita Beltrán-Sánchez Alistair Hernández-Izquierdo José Luis SalvadorHernández Eduardo Salcedo-Pérez Rosa E. del Río Mauro M. Martínez Pacheco 《Phyton》2021,90(3):907-920
This study scrutinized the possibility of finding toxicant or deterrent plant metabolites against the dry wood termite Incisitermes marginipennis (Latreille). Plant deterrent agents act as repellents or antifeedants to prevent
wood decay and increase its useful life. The potential of the tree Caesalpinia coriaria (Fabaceae) as a biological
source of molecules with deterrent effects against the dry wood termite was assessed by a phytochemical fractionation guided by repellence and antifeedant activities. The gas chromatography-mass spectrometry analysis of the
leaf essential oil showed geraniol to be one of the major components and its repellent and antifeedant effects were
determined. Geraniol had only an antifeedant effect without affecting the body weight or survival of the dry wood
termite. Unlike the leaf essential oil, geraniol did not exhibit a repellency effect. An in-silico approach of the activity of acetylcholinesterase in interaction with geraniol resulted in an affinity energy of −7.5 Kcal/mol. Geraniol
interacted with the amino acid tyrosine 324 located in the enzyme’s active site while citronellol (negative control)
interacted with tryptophan 83 located adjacent to the active site. These deterring terpenes have not been implemented for the preservation and restoration of wood products exposed to the attack of the dry wood termite.
However, they are an important natural control alternative. 相似文献
104.
Choosing what scientific project to pursue is the most important decision that scientists at all levels continually face. Time devoted to a project can further desirable knowledge and advance a career or cost years in lost opportunity. Knowing what to consider before embarking on a specific scientific journey, as well as when to drop a project and change course, offers a way of practicing science that keeps us mindful of what is relevant at a given time and place while preserving our freedom to explore the most exciting findings. This article explores both the pressures that restrict this delicate decision-making process and the processes that scientists can apply to overcome those pressures. Above all else, as it turns out, we must still love the pursuit of knowledge for its own sake – and this love directly impacts our results. 相似文献
105.
Jonathan C. Guito Joseph B. Prescott Catherine E. Arnold Brian R. Amman Amy J. Schuh Jessica R. Spengler Tara K. Sealy Jessica R. Harmon JoAnn D. Coleman-McCray Kirsten A. Kulcsar Elyse R. Nagle Raina Kumar Gustavo F. Palacios Mariano Sanchez-Lockhart Jonathan S. Towner 《Current biology : CB》2021,31(2):257-270.e5
106.
Castañeda-Pérez Eduardo Jiménez-Morales Karina Castellanos-Ruelas Arturo Chel-Guerrero Luis Betancur-Ancona David 《International journal of peptide research and therapeutics》2021,27(3):1979-1988
International Journal of Peptide Research and Therapeutics - Characterized by uncontrolled, long-term high blood sugar levels, diabetes mellitus affects ever increasing numbers of people worldwide.... 相似文献
107.
Flávio A. Carvalho Fernando B. Oda Eduardo J. Crevelin Antônio E. M. Crotti André G. dos Santos 《化学与生物多样性》2021,18(6):e2000880
Casearia sylvestris is an endemic tree of the Latin America that the essential oil (EO) has anti-inflammatory and gastroprotective actions. This study evaluates the chemical composition of the EO from the volatile fractions of in natura, fresh, and dried C. sylvestris var. sylvestris and var. lingua leaves. For both varieties, the dried leaves presented higher EO yield as compared to fresh leaves. The major EO chemical components were (E)-caryophyllene, α-humulene, germacrene D, bicyclogermacrene, spathulenol, caryophyllene oxide, and humulene epoxide II. In both varieties, the content of sesquiterpene hydrocarbons decreased and oxygenated sesquiterpenes increased on going from in natura to fresh and dried leaves, which indicated that leaf drying and hydrodistillation modified the volatile composition. The results also suggested that bicyclogermacrene and (E)-caryophyllene were oxidized during processing, to generate spathulenol and caryophyllene oxide, respectively. C. sylvestris varieties and in natura, fresh, and dried leaves differed in terms of the chemical composition of volatiles, which could affect the EO biological activities. 相似文献
108.
Jardón-Valadez Eduardo Chen Charles H. García-Garibay Mariano Jiménez-Guzmán Judith Ulmschneider Martin B. 《Food biophysics》2021,16(1):70-83
Food Biophysics - Absorption of bioactive peptides in the intestinal epithelium take place in the apical or the basolateral tight junctions of the cells. Depending on the peptide size and... 相似文献
109.
Calmasini Fabiano B. Alexandre Eduardo C. Oliveira Mariana G. Silva Fábio H. Soares António G. Costa Soraia K.P. Antunes Edson 《Journal of physiology and biochemistry》2021,77(4):557-564
Journal of Physiology and Biochemistry - Lipopolysaccharide (LPS) is a component of gram-negative bacteria wall that elicits inflammatory response in the host through the toll-like receptor 4... 相似文献
110.
Ilie S. Racotta Elena Palacios Lia MÉndez 《Marine and Freshwater Behaviour and Physiology》2013,45(4):269-275
Anaerobic metabolism and oxygen carrying-capacity of white shrimp (Penaeus vannamei) exposed to short term (three days) and long term (two weeks) moderate hypoxia (2-2.6 mg/L) was investigated. Glucose and lactate levels in hemolymph increased under both hypoxic conditions, indicating an activation of anaerobic pathways during the two-weeks exposure period. In muscle, no differences of glucose and lactate levels were observed between the control group and the exposed groups. In animals exposed to hypoxia for two weeks, hemocyanin and copper in hemolymph were higher than in animals under normoxic conditions or exposed for three days. These results indicate that an increase in oxygen carrying-capacity in shrimp is evident only after a sustained condition of hypoxia. Copper levels in the hepatopancreas decreased in both hypoxic conditions, suggesting a mobilization of copper stores for hemocyanin synthesis. These results indicate that penaeid shrimp can tolerate moderate hypoxic conditions by physiological adaptations, such as anaerobic metabolism and increased oxygen carrying-capacity. These adaptations require an adequate dietary supply of proteins and copper for hemocyanin synthesis and of carbohydrates for anaerobic metabolism. 相似文献