The prayer book The Hours of the Blessed Virgin Mary, known as The Farnese Hours, was illustrated by the Croatian miniaturist, Julije Klović, between 1539 and 1546 in Rome. In this masterpiece of Renaissance
miniature art, Klović drew in colour a bird of paradise. In 2001, the pictured bird was determined to be a Raggiana Bird of
Paradise, Paradisaea raggiana P. L. Sclater 1873. Our later determination shows that it is actually a Greater Bird of Paradise Paradisaea apoda (Linnaeus 1758) and the first drawing of this species in colour in Europe. Klović’s model for the Greater Bird of Paradise
was one of the first trade skins of birds of paradise that, from 1522, had been arriving in Europe. Revision of the early
drawings of the birds of paradise species in Europe, relevant to the Klović drawing model, has also been carried out and is
discussed. 相似文献
Two gastropod assemblages from the Carnian (Upper Triassic) Raibl Beds of the Mežica region (Karavanke Mountains, Slovenia) are described. The almost monospecific, older assemblage from Mežica Mine was found as a thin shell pavement in the clastic sequence. This association apparently originated during a period of reduced sedimentation. The younger assemblage from Helena Creek was found at the upper surface of an oolitic and oncoidal limestone and represents a more diversified fauna of a crinoid/coelenterate/polychaete meadow. Together, both assemblages contain 11 gastropod species. Five of them are left in open nomenclature, two are known from other localities in the Alps, and the remaining four are new. The new species are Sloeudaronia karavankensis (Skeneidae), Helenostylina mezicaensis (Coelostylinidae), Ampezzopleura slovenica and Striazyga crnaensis (Zygopleuridae). Two new genera, Sloeudaronia (Skeneidae) and Helenostylina (Coelostylinidae), are described.An erratum to this article can be found at 相似文献
During cultivation of the filamentous fungus Lentinus tigrinus on a medium containing lignin, a high oxygen content stimulated the growth of the fungus and contributed to the yield of lipids. A high content of phosphatidic acid and a reduction in the level of phosphatidylethanolamine and phosphatidylserine were first detected in the composition of phospholipids. Changes in the composition of neutral lipids, such as variation in the ratio of esterified and free sterols, have occurred; thus, the amount of sterol esters reduced simultaneously with a decrease in the content of free fatty acids. Based on the obtained results, the possible role of phosphatidic acid as a second messenger in the process of the consumption of lignin by the fungus Lentinus tigrinus is discussed. 相似文献
We examined whether a variable-number tandem repeat (VNTR) polymorphism in the circadian clock gene PER3 was associated with subjective ratings of sleep and diurnal preference in a Romanian population with high levels of self-reported sleep problems. Individuals, self-reporting to their GP for sleep disturbances, completed a battery of validated scales that assess the presence of insomnia, sleep quality and diurnal preference and had their PER3 VNTR genotype determined. We found no significant differences in chronotype, sleep quality or other psychometric measures according to PER3 VNTR and conclude that diurnal preference or self-reported sleep measures are not associated with PER3 genotype in this population.
Mesenchymal stromal cells (MSC) are attractive tools for cell-based therapy, yet the mechanisms underlying their migration and survival post-transplantation are unclear. Accumulating evidence indicates that MSC apoptosis modulates both innate and adaptive immune responses which impact on MSC therapeutic effects. Using a dual tracking system, namely the Luciferase expression and VivoTrack680 labelling, and in vivo optical imaging, we investigated the survival and migration of MSC transplanted by various routes (intravenous, subcutaneous, intrapancreatic and intrasplenic) in order to identify the best delivery approach that provides an accumulation of therapeutic cells to the injured pancreas in the non-obese diabetic (NOD) mouse. The results showed that transplanted MSC had limited migration capacity, irrespective of the administration route, and were short-lived with almost total disappearance at 7 days after transplantation. Within one day after transplantation, cells activated hypoxia signalling pathways, followed by Caspase 3-mediated apoptosis. These were subsequently followed by local recruitment of immune cells at the transplantation site, and the engulfment of apoptotic MSC by macrophages. Our results argue for a “hit and die” mechanism of transplanted MSC. Further investigations will elucidate the molecular crosstalk between the inoculated and the host-immune cells.Subject terms: Apoptosis, Mesenchymal stem cells相似文献
Germinating seeds of spring wheat (Triticum aestivum L.) were tolerant to dehydration up to the 4th day following imbibition and from the 5th day the seedling survival decreased. Dehydration also inhibited the rate of seed dry mass depletion and seedling dry matter accumulation and increased the content of soluble sugars both in grain and seedlings. Glucose supplied either to dry seeds or to 4-d-old seedlings increased survival of dehydrated seedlings. In contrast, exogenously supplied non-readily metabolizable sorbose and mannose suppressed seedling survival. 相似文献
By differential centrifugation method a lysosomal fraction was obtained from five species of cestodes, which possesses the highest specific activity of acidic phosphatases as compared to other subcellular fractions. By isopyknic centrifugation in the density gradient of saccharose the lysosomal fraction is divided into primary and secondary lysosomes. Lysosomes of cestodes are similar to those of vertebrate animals in the character of fractional distribution of acidic phosphatase, sedimentation abilities and sensitivity of membranes to triton X-100. 相似文献
Two outbreaks of botulism in central Saskatchewan in which mortality of waterfowl continued into late autumn and then recurred in the same marshes the following spring are described. Small numbers of birds were involved in each instance. Dabbling ducks (predominantly mallards, Anas platyrhynchos and pintails, Anas acuta) and American coots, Fulica americana were affected most commonly in autumn, whereas only diving ducks (predominantly lesser scaup, Aythya affinis) were found to be involved in spring. Live maggots present in carcasses despite sub-freezing temperatures were the probable source of intoxication in the autumn; the source of toxin in the spring was not determined. 相似文献
Theoretical investigations (Perturbative Configuration Interaction over Localized Orbitals (PCILO) and Intermediate Neglect of Differential Overlap (INDO) methods) of the conformation of tetramethylcystosine, an overcrowded molecule with planar struture, have carried out. The Physical features of rotational bending potentials of the dimethylamimo group are discussed. Particulary, the controversial problem concerning the planarity of the molecule is investigated. The obtained results show that the planarity of tetrathylcytosine is an intrinsic property of the molecule. Nevertheless, because of the repulsion between the methyl groups, the planar structure of tetramethylcytosine is slightly destabilized. Further, the functional dependence of the dipole moment of tetramethylcytosine on rotation and bending of the dimethylamino group has been analyzed. 相似文献