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Laura Curatolo Maria Grazia Alessio Bruno Casali Anna Falanga Maria Benedetta Donati Nicola Semeraro 《In vitro cellular & developmental biology. Plant》1989,25(4):388-388
The online version of the original article can be found at 相似文献
374.
Sonia Floris Antonella Fais Rosaria Medda Francesca Pintus Alessandra Piras Amit Kumar Piotr Marek Ku Gunilla Torstensdotter Westermark Benedetta Era 《Journal of enzyme inhibition and medicinal chemistry》2021,36(1):517
Washingtonia filifera seeds have revealed to possess antioxidant properties, butyrylcholinesterase and xanthine oxidase inhibition activities. The literature has indicated a relationship between Alzheimer’s disease (AD) and type-2 diabetes (T2D). Keeping this in mind, we have now evaluated the inhibitory properties of W. filifera seed extracts on α-amylase, α-glucosidase enzyme activity and the Islet Amyloid Polypeptide (IAPP) fibrils formation.Three extracts from seeds of W. filifera were evaluated for their enzyme inhibitory effect and IC50 values were calculated for all the extracts. The inhibition mode was investigated by Lineweaver-Burk plot analysis and the inhibition of IAPP aggregate formation was monitored.W. filifera methanol seed extract appears as the most potent inhibitor of α-amylase, α-glucosidase, and for the IAPP fibril formation.Current findings indicate new potential of this extract that could be used for the identification or development of novel potential agents for T2D and AD. 相似文献
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Ciro Sannino Luigimaria Borruso Ambra Mezzasoma Dario Battistel Laura Zucconi Laura Selbmann Maurizio Azzaro Silvano Onofri Benedetta Turchetti Pietro Buzzini Mauro Guglielmin 《Environmental microbiology》2020,22(8):3463-3477
A perennially frozen lake at Boulder Clay site (Victoria Land, Antarctica), characterized by the presence of frost mounds, have been selected as an in situ model for ecological studies. Different samples of permafrost, glacier ice and brines have been studied as a unique habitat system. An additional sample of brines (collected in another frozen lake close to the previous one) was also considered. Alpha- and beta-diversity of fungal communities showed both intra- and inter-cores significant (p < 0.05) differences, which suggest the presence of interconnection among the habitats. Therefore, the layers of frost mound and the deep glacier could be interconnected while the brines could probably be considered as an open habitat system not interconnected with each other. Moreover, the absence of similarity between the lake ice and the underlying permafrost suggested that the lake is perennially frozen based. The predominance of positive significant (p < 0.05) co-occurrences among some fungal taxa allowed to postulate the existence of an ecological equilibrium in the habitats systems. The positive significant (p < 0.05) correlation between salt concentration, total organic carbon and pH, and some fungal taxa suggests that a few abiotic parameters could drive fungal diversity inside these ecological niches. 相似文献