全文获取类型
收费全文 | 710篇 |
免费 | 77篇 |
出版年
2023年 | 5篇 |
2022年 | 3篇 |
2021年 | 7篇 |
2020年 | 8篇 |
2019年 | 9篇 |
2018年 | 14篇 |
2017年 | 8篇 |
2016年 | 11篇 |
2015年 | 22篇 |
2014年 | 32篇 |
2013年 | 42篇 |
2012年 | 55篇 |
2011年 | 57篇 |
2010年 | 39篇 |
2009年 | 27篇 |
2008年 | 40篇 |
2007年 | 43篇 |
2006年 | 36篇 |
2005年 | 46篇 |
2004年 | 30篇 |
2003年 | 26篇 |
2002年 | 34篇 |
2001年 | 10篇 |
2000年 | 19篇 |
1999年 | 16篇 |
1998年 | 5篇 |
1997年 | 3篇 |
1996年 | 12篇 |
1995年 | 11篇 |
1994年 | 3篇 |
1993年 | 6篇 |
1992年 | 7篇 |
1991年 | 7篇 |
1990年 | 9篇 |
1989年 | 4篇 |
1988年 | 5篇 |
1985年 | 4篇 |
1983年 | 4篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1978年 | 3篇 |
1976年 | 6篇 |
1975年 | 5篇 |
1974年 | 4篇 |
1973年 | 6篇 |
1972年 | 4篇 |
1970年 | 3篇 |
1960年 | 3篇 |
1929年 | 2篇 |
1925年 | 5篇 |
排序方式: 共有787条查询结果,搜索用时 0 毫秒
781.
Biological invasions constitute major threats to global biodiversity. Eco‐evolutionary considerations highlight the importance of contemporary evolution in community responses to bioinvasions. However, effects of metapopulation structure on invasion success have been mostly overlooked even though metapopulation structure determines gene flow and is likely to affect evolutionary processes. Here, we investigate a stepping‐stone model with evolving alien native interaction strengths. We demonstrate analytically that the site of invasion can determine the success of an invading consumer because gene flow and demography of a local resource species interact to obstruct local resource adaptation. Our main results are 1) that invasion success is more likely in genetic sink populations of the native species and 2) that invasion is more likely to occur against the migrational flow of native species. These findings suggest that invasibility is best regarded as an emergent property not only of communities but of entire metapopulations. Since migration networks of aliens and natives are often mismatched due to anthropogenic interference, our results indicate how population structure eases the spread of invasives against the migrational flow of natives. 相似文献
782.
The effects of supernatants of primary and secondary malignant human lymphoma cell cultures were analyzed as parameters of spontaneous secretion of factors by these cells using the leukocyte migration test (LMT). Spontaneous cultivation for up to five weeks was successful in four cases. The postulated production of mediators, i.e. the inhibitory and stimulating effects on leukocyte migration were characterized by testing the influence of (a) concentration, (b) temperature and (c) absorption with normal blood leukocytes on the effect. Reproducible stimulatory and inhibitory effects on the migration of normal leukocytes were dependent on concentration and temperature and were apparently mediated by one or more factors. The supernatants of a lymphoblastic lymphosarcoma of the T-cell type and of a lymphoblastic lymphosarcoma clearly revealed congruous and reproducible inhibitory effects. A further case of lymphoblastic lymphosarcoma that could not exactly be defined with immunological methods either and a case of centroblastic/centrocytic lymphosarcoma exhibited stimulating effects which could be reduced in a time-dependent manner through preincubation with blood leukocytes. The results of these studies support the assumption that malignant lymphoma cells are capable not only of secreting immunoglobulin, but also of other biologically effective secretion. The effects of such secretion are differentiated into stimulating and inhibitory ones. They might be important for the spreading of a tumor or for resistance of the organism to the disease. 相似文献
783.
784.
Pablo Quintela‐Alonso Frank Nitsche Claudia Wylezich Hartmut Arndt Wilhelm Foissner 《The Journal of eukaryotic microbiology》2013,60(3):235-246
The identification of species within the genus Tetrahymena is known to be difficult due to their essentially identical morphology, the occurrence of cryptic and sibling species and the phenotypic plasticity associated with the polymorphic life cycle of some species. We have combined morphology and molecular biology to describe Tetrahymena aquasubterranea n. sp. from groundwater of Cape Town, Republic of South Africa. The phylogenetic analysis compares the cox1 gene sequence of T. aquasubterranea with the cox1 gene sequences of other Tetrahymena species and uses the interior‐branch test to improve the resolution of the evolutionary relationships. This showed a considerable genetic divergence of T. aquasubterranea to its next relative, T. farlyi, of 9.2% (the average cox1 divergence among bona fide species of Tetrahymena is ~ 10%). Moreover, the analysis also suggested a sister relationship between T. aquasubterranea and a big clade comprising T. farleyi, T. tropicalis, T. furgasoni and T. mobilis. The morphological data available for these species show that they share with T. aquasubterranea a pyriformis‐like life style and at least two of them, T. farleyi and T. mobilis, a similar type II silverline pattern consisting of primary and secondary meridians. Tetrahymena aquasubterranea exhibits a biphasic life cycle with trophonts and theronts, is amicronucleate, and feeds on bacteria. 相似文献
785.
786.
787.
The synthesis of prostaglandin analogs incorporating the 3-hydroxycyclohexenyl moiety in place of the natural C13-C20 side-chain has been accomplished via copper-assisted conjugate addition of the cycloalkenyllithium 2 to the cyclopentenous intermediates 4, 7 and 10. 相似文献