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991.
Predicting the sensory consequences of saccadic eye movements likely plays a crucial role in planning sequences of saccades and in maintaining visual stability despite saccade-caused retinal displacements. Deficits in predictive activity, such as that afforded by a corollary discharge signal, have been reported in patients with schizophrenia, and may lead to the emergence of positive symptoms, in particular delusions of control and auditory hallucinations. We examined whether a measure of delusional thinking in the general, non-clinical population correlated with measures of predictive activity in two oculomotor tasks. The double-step task measured predictive activity in motor control, and the in-flight displacement task measured predictive activity in trans-saccadic visual perception. Forty-one healthy adults performed both tasks and completed a questionnaire to assess delusional thinking. The quantitative measure of predictive activity we obtained correlated with the tendency towards delusional ideation, but only for the motor task, and not the perceptual task: Individuals with higher levels of delusional thinking showed less self-movement information use in the motor task. Variation of the degree of self-generated movement knowledge as a function of the prevalence of delusional ideation in the normal population strongly supports the idea that corollary discharge deficits measured in schizophrenic patients in previous researches are not due to neuroleptic medication. We also propose that this difference in results between the perceptual and the motor tasks may point to a dissociation between corollary discharge for perception and corollary discharge for action. 相似文献
992.
The lipid modification of membrane proteins was investigated in Acholeplasma laidlawii by metabolic labeling and by chemical analysis. A S-glycerylcysteine residue was identified from membrane proteins and we reported the strong preference for saturated acyl chains
into the lipid modification. Differential release of fatty acids revealed a ratio [(O-ester- + amide-bound acyl chains)/O-ester-linked chains] close to 1.1 which suggests the involvement of only two O-ester linked fatty acids in the acylation process. Present data indicate that acyl proteins in A. laidlawii are true lipoproteins (mainly diacylated) probably processed by a mechanism analogous to that described for eubacteria and
other mycoplasmas.
Received: 9 March 2001 / Accepted: 17 April 2001 相似文献
993.
994.
Combined effects of partial root drying and patchy fertilizer placement on nutrient acquisition and growth of oilseed rape 总被引:2,自引:0,他引:2
Partial rootzone drying (PRD) is widely investigated as an effective irrigation technique, resulting in higher water use efficiency
and yield for plants growing under mild water deficit. Nutrition is another important factor affecting plant yield, but nutrient
acquisition has only rarely been considered in conjunction with PRD. Here we investigate the interaction between water and
fertilizer supply in a pot experiment with oilseed rape (Brassica napus L.). Eight treatments were set up for the experiment, a factorial combination of four watering regimes (100% control watering
at both sides of the plants; 50% control watering at both sides of the plants; 50% fixed watering applied only to one side
of the plants; 50% alternate watering applied alternately to both sides of the plant) and two fertilizer placement levels
(uniform over the entire pot, and patchy supplied to one side). For the 50% watering treatments, the total amount of water
supplied to the plants was the same, only the pattern of application differed between treatments. Also the total fertilizer
applied was the same for all treatments. Oilseed rape roots foraged effectively for water and nutrients resulting in relatively
small differences in nutrient uptake and above-ground growth among the water-deficit treatments. Placing fertilizer at one
side of the plants increased nutrient uptake, but there were differences between the water treatments and interactions with
water uptake. Alternate watering resulted in the highest growth, as a result of the largest nitrogen and phosphorus uptake
with the smallest root investment among the three water deficit treatments. Fixed watering resulted in poorest performance
when fertilizer was uniformly spread throughout the pot, because the plants were unable to acquire the nutrients on the dry
side. Our results show that PRD can be well combined with patchy fertilizer supply, but that reduced nutrient uptake may be
expected when nutrients are supplied in parts of the soil volume that remain too dry.
Responsible Editor: Yan Li 相似文献
995.
996.
Catherine Bchade Cyrille Sur Antoine Triller 《BioEssays : news and reviews in molecular, cellular and developmental biology》1994,16(10):735-744
Glycine is a major inhibitory neurotransmitter in the spinal cord and in the brain stem, where it acts by activating a chloride conductance. The postsynaptic glycine receptor has been purified and contains two transmembrane subunits of 48 kDa (α) and 58 kDa (β), and a peripheral membrane protein of 93 kDa. cDNA sequencing of the α and β subunits has revealed a common structural organization and a strong homology between these polypeptides and the nicotinic acetylcholine and GABAA receptor proteins. The glycine receptor exhibits a heterogeneity resulting from the existence of several α subtypes with distinct functional properties and different developmental expressions. When present in the central nervous system in situ, as well as in primary cultures of spinal cord neurons, these receptors are localized at the postsynaptic membrane adjacent to the presynaptic release sites, thus forming functional microdomains at the neuronal surface. This distribution raises the question of the formation and the maintenance of the heterogeneity of the somato-dendritic plasma membrane. 相似文献
997.
998.
The aim of this study was to ascertain the influence of environmental variables on the seasonal variations of total animal biomass in temporary ponds. We thus collected weekly, in seven major types of mosquito-breeding habitats, a total of 163 samples and calculated the dry weight (µg/l) of 75 taxa, using the length-weight relationships described in the literature. The total biomass was found to be more stable than the proportions of individual taxa. Multiple regression analysis showed that most of the dispersion of total animal biomass could be explained by environmental variables, especially water temperature, volume of water body and season. 相似文献
999.
A new species of Avrainvillea was found on the South Pacific island of Rotuma, Fiji. Avrainvillea rotumensis sp. nov. occurs 1.5-3.0 m deep in a high energy current area of the Hoféa Passage, one of the few openings in the fringing reef that surrounds the island. The distinctive peltate growth habit of A. rotumensis is unique for the genus and facilitates quick and accurate field identification. The peltate blade (7–9 cm in diameter at maturity) is unusually thick (34 mm) tapering toward a short (up to 6 cm in length), thick (1.5-2.0 cm in diameter) stipe. 相似文献
1000.
The effect of the calcium channel blocker nimodipine on the previously described regional cerebral acidosis accompanying thiamine deficiency was investigated. Local cerebral pH (LCpH) and blood flow (LCBF) were separately determined autoradiographically in normal and 16-day thiamine-deficient rats administered the calcium antagonist drug and compared to appropriate controls. Nimodipine did not modify LCpH in normal brain. In thiamine deficiency, nimodipine significantly raised LCpH in 5 of 17 structures evaluated, two of which, the medial dorsal nucleus of the thalamus and the mammillary body, are vulnerable to the development of histological lesions in this condition. Although the calcium blocker augmented LCBF in normal brain, it had no effect on the hyperperfusion already present by day 16 of thiamine deprivation. Thus, the pH changes we are reporting are probably not related to an effect on cerebral perfusion, but could have resulted from an improved ability of the brain to reduce its proton load in the presence of nimodipine. These results may have wider therapeutic implications than in thiamine deficiency alone. 相似文献