排序方式: 共有131条查询结果,搜索用时 31 毫秒
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Functional interrelationship between TFII‐I and E2F transcription factors at specific cell cycle gene loci 下载免费PDF全文
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Arora Shiyana Venugopalan Aishwarya Dharavath Ravinder Naik Bishnoi Mahendra Kondepudi Kanthi Kiran Chopra Kanwaljit 《Neurochemical research》2021,46(5):1177-1187
Neurochemical Research - Growing experimental evidences have suggested the reciprocal correlation between sleep deprivation and pain. Inflammation and oxidative stress are among the key pathways... 相似文献
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Kumar Naveen Chaudhary Aishwarya Singh Deepali Teotia Sachin 《Journal of plant biochemistry and biotechnology.》2020,29(4):754-768
Journal of Plant Biochemistry and Biotechnology - Triacylglycerols (TAGs) are derived from ester linkage of fatty acids (FAs) and glycerol and stored by plants in their seeds as carbon and energy... 相似文献
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Nagampalli S. A. Krushna Chandanpurath Shiny Srinivasan Dharanya Arivazhagan Sindhu Sridharan Aishwarya Rangarajan B. Narayanan 《Microbiology and immunology》2009,53(3):173-183
cDNA coding for Brugia malayi pepsin inhibitor homolog (Bm-33) from the human filarial parasite was cloned in pRSET for large-scale expression and functional characterization. The pRSET-B cloned gene did not yield recombinant protein expression and the reason was attributed to the presence of an N-terminal signal peptide. The gene was subcloned in pRSET-A without a signal peptide and the 33 kDa histidine-tagged recombinant protein was purified by IMAC. All individuals from an endemic area generated IgG responses against Bm-33 in the order MF>CP>EN. Isotype analysis indicated an elevated IgG4 reactivity in the order MF>EN>CP. Bm-33-specific IgE levels were elevated in MF, CP and EN compared to non-endemic normals with no significant differences among the groups. Paraffin-embedded sections of Setaria digitata (cattle filarial parasite) stained with mouse anti-Bm-33 antibodies exhibited the hypodermal nature of Bm-33. These findings suggest that Bm-33 is an immunodominant antigen and contributes to filarial pathogenesis. 相似文献
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Taj SA Gurumurthy P Suresh R Narayanan S Suman Meenakshi S Sanghvi YS 《Nucleosides, nucleotides & nucleic acids》2003,22(5-8):1327-1330
An efficient four step process for the preparation of 5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-O-(2-methoxyethyl)-guanosine 1 was developed. Direct 2'-O-alkylation of 2,6-diaminopurine riboside 2 was accomplished via inexpensive and commercially available reagents such as KOH, DMSO and alkyl halides at room temperature in 4-6 hrs. Pure 2'-O-(2-methoxyethyl)-DAPR 3 was isolated by crystallization from methanol. Enzymatic deamination of 3 followed by selective N2-isobutyrylation and 5'-O-dimethoxytritylation furnished desired 1 in high yield and purity. Fully optimized four step synthetic process has been scaled up to the pilot plant level. 相似文献
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