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21.
Tuo Fu ZHU Tie Jian FENG Xin XIAO Hui WANG Bo Ping ZHOU 《Cell research》2005,15(11):833-842
Genetic polymorphisms in human genes can influence the risk for HIV-1 infection and disease progression, although the reported effects of these alleles have been inconsistent. This review highlights the recent discoveries on global and Chinese genetic polymorphisms and their association with HIV-1 transmission and disease progression. 相似文献
22.
Xiang Ping LI Shun Zhen XIAO * Qiao Qin WAN Sen Lin SONG Yan Xia TENG School of Nursing Peking University Beijing China Department of Psychiatry DaXing Hospital Beijing Drug Abuse Treatment Center Beijing China 《Cell research》2005,(Z1)
INTRODUCTION Today, Acquired Immunodeficiency Syndrome (AIDS) has become a public health and social problem that has caused significant harm to the survival and development of humanbeings. Route of transmission of Human Im- munodeficiency Virus (HIV) is still predominantly through shared syringes by drug abusers. Currently, there is no efficient medicine, treatment or educational method to prevent HIV transmission in China. Intervention is prob- ably the best “vaccine” [1]. Despi… 相似文献
23.
XI CHEN WEI ZHANG YUN FEI GAO XIAO QIN SU ZHONG HE ZHAI * College of Life Sciences Peking University Beijing China The Key Laboratory of Cell Proliferation Regulation Biology of the Ministry of Education College of Life Sciences 《Cell research》2002,(Z1)
P21Waf1/Cip1 is a potent cyclin-dependent kinase inhibitor. As a downstream mediator of p53, p21Waf1/Cip1 involves in cell cycle arrest, differentiation and apoptosis. Previous studies in human cells provided evidence for a link between p21Waf1/Cip1 and cellular senescence. While in murine cells, the role of p21Waf1/Cip1 is indefinite. We explored this issue using NIH3T3 cells with inducible p21Waf1/Cip1 expression. Induction of p21Waf1/Cip1 triggered G1 growth arrest, and NIH3T3-p21 cells exhibited morphologic features, such as enlarged and flattened cellular shape, specific to the senescence phenotype. We also showed that p21Waf1/Cip1-transduced NIH3T3 cells expressed β-galactosidase activity at pH 6.0, which is known to be a marker of senescence. Our results suggest that p21Waf1/Cip1 can also induce senescence-like changes in murine cells. 相似文献
24.
Depolymerization of actin cytoskeleton is involved in stomatal closure-induced by extracellular calmodulin in Arabidopsis 总被引:2,自引:0,他引:2
XIAO Yumei CHEN Yuling HUANG Rongfeng CHEN Jia & WANG Xue-chen . The National Key Laboratory of Plant Physiology Biochemistry College of Biological Sciences China Agricultural University Bei-jing China . College of Life Sciences Hebei Normal University Shijiazhuang China . Biotechnology Research Institute Chinese Academy of Agricultural Sciences Beijing China 《中国科学:生命科学英文版》2004,47(5):454-460
CaM ubiquitously presents inside eukaryotic cells. CaM抯 gene expression and its subcellular localization are regulated by light, osmotic stress, pathogens, plant hormones, etc.[1]. Intracellular CaM of plant displays important functions in pathogenesis and wounding reaction[2] and hypersensitive response[3]. CaM has been found extracellular spaces in many plant species, such as soluble extracts of oat coleoptile cell walls[4], the wheat coleoptile cell walls[5], maize root tips cell walls[6… 相似文献
25.
Discovery of laryngeal carcinoma by serum proteomic pattern analysis 总被引:15,自引:1,他引:14
XIAO Xueyuan ZHAO Xiaodong LIU Jiankai GUO Fuzheng LIU Danhui & HE Dacheng . Key Laboratory for Cell Proliferation Regulation Biology Ministry of Education Beijing Normal University Universities?Confeder-ated Institute of Proteomics Beijing China . Department of Otolaryngology-Head Neck Surgery Third Affiliated Hospital Jilin University Changchun China . Department of Biochemistry Jilin University Changchun China 《中国科学:生命科学英文版》2004,47(3):219-223
Laryngealcarcinomaisthemostcommonma-lignancyamongtheheadandneckcarcinomas.Theincidenceoflaryngealcanceraccountsforapproxi-mately5%ofmalignanttumorsinthepopulationofdevelopedcountries[1].Laryngealcarcinomahasthreesubtypes,whichincludesupraglottis,glottisandsub-glottis.Amongthem,glottisisthemostcommononeandaffectsmorethan50%ofallthelaryngealcancerpatients.Thoughlaryngoscopyisthemainstayforla-ryngealcancerdetectionbecauseofitsgeneralavail-ability,diagnosisisconfirmedbybiopsyofthepri-marylesion.E… 相似文献
26.
Haoqi YU Yuanfei WANG Liuyang HE Yudong ZHU Xiuqin LIN Luyao XIAO Cheng LI Jianping JIANG Feng XIE 《亚洲两栖爬行动物研究(英文版)》2023,(3):227-236
Many animals migrate during the breeding season. It is important to study the patterns of breeding migration of wild animals, especially rare and endangered species. However, current data acquisition methods are too coarse and imprecise for investigating the circadian rhythms of migrations in amphibians. Based on the frustrated total reflection image(FTRI), we developed a new device and recorded the precise migration time of an endangered salamander, Liangshantriton taliangensis.During the breed... 相似文献
27.
红火蚁Solenopsis invicta Buren是一种严重的入侵物种,工蚁具有很强的攻击性,活动迅速,给采样带来了一定的困难.本文设计了红火蚁工蚁的定量采集装置、诱饵上工蚁的活体分装与计数装置以及工蚁的分级装置,并提供了制作和使用方法.这些装置及方法可为红火蚁的室内研究工作提供安全可靠的实验方法. 相似文献
28.
Lake Level Changes Recorded by Tree Rings of Lakeshore Shrubs: A Case Study at the Lake West-Juyan, Inner Mongolia, China 总被引:4,自引:0,他引:4
Sheng-Chun XIAO Hong-Lang XIAO Jian-Hua SI Xi-Bin JI Fa-Min LIU 《植物学报(英文版)》2005,47(11):1303-1314
Variation in water resources is a main factor influencing ecohydrological processes and sustainable development in arid regions. Lake level changes are a useful indicator of the variability in water resources. However, observational records of changes in lake levels are usually too short to give an understanding of the long-term variability. In the present study, we investigated the tree rings of shrubs growing on the lakeshore of Lake West-Juyan, the terminus of the Heihe River in western China, and found that Lake West-Juyan had undergone degradation three times over the past 200 years. The lake level decreased from 904.3 to 896.8 m above sea level (a.s.1.) during the period 1800-1900, to 892.0 m a.s.1, from around 1900 to the late 1950s, and the lake dried out in 1963. The trend for changes in lake levels, which was represented by the composite chronology of three beach bars, showed that the phases of increasing lake levels over the past 150 years were during the periods 1852-1871, 1932-1952, 1973-1982, and 1995-1999. Comparison with the history of regional economic development showed that human activity has played an important role in regulating the water resources of the lower reaches of the Heihe watershed over the past 200 years. 相似文献
29.
MA YINGHUA JIA HUA HU WEN JUAN ZHAO JIAN FEI YUN YU XIAO GANG ZHOU ZHEN TONG MEI LI HE GUO 《Cell research》2001,(1)
INTroDUCTION.7-aminobutyric acid (GABA), a major in-hibitory neurotransmitter in vertebrate brain, in--duces neuronal inhibition via GABA receptors. Adeficiency of GABAergic inhibition has been hy-pothesized to be a principal factor in the patho-genesis of epilepsy[1]. GABA transporters are im-portant components of the GABAergic system, andfunction in part to terminate the GABA transmis-sion through rapid re-uptake of GABA into thepresynaptic neurons and surrounding gliaJ cells[2… 相似文献
30.