The complete mitochondrial genomes sequences of Asio flammeus and Asio otus and comparative analysis

Mitochondrial DNA (mtDNA), as a model sys-tem, has been extensively used for molecular phy-logenetic and evolutionary analysis[1]. With the ad-vances in DNA sequencing technology, more andmore researchers prefer to use complete mitochondrialgenome for phylogenetic analysis[2—4]. Since the com-plete sequencing of human mtDNA in 1981 (Andersonet al., 1981)[5], 342 vertebrate mitochondrial genomeshave so far been sequenced. Up to now the completesequences of 29 avian mitochondrial genomes h…     

Screening and identification of Shigella flexneri 2a virulence-related genes induced after invasion of epithelial cells

~~Screening and identification of Shigella flexneri 2a virulence-related genes induced after invasion of epithelial cells1. Jin, Q., Yuan, Z., Xu, J., Wang, Y., Shen, Y., Lu, W., Wang, J., Liu, H., Yang, J., Yang, P., Zhang, X., Zhang, J., Yang, G, Wu, H., Qu, D., Dong, J., Sun, L., Xue, Y, Zhao, A., Gao, Y., Zhu, J., Kan, B., Ding, K.. Chen, S., Cheng, H., Yao, Z., He, B., Chen, R., Ma, D., Qiang, B., Wen, Y, Hou, Y., Yu, J., Genome sequence of Shigella flexneri 2…     

Identification and expression profiling of putative odorant-binding proteins in the malaria mosquitoes, Anopheles gambiae and A.arabiensis

~~Identification and expression profiling of putative odorant-binding proteins in the malaria mosquitoes, Anopheles gambiae and A. arabiensis1. Curtis, C. F., Introduction 1: An overview of mosquito biology, behaviour and importance, in Olfaction in Mosquito-Host Interactions (eds. Bock, G. R.. Cardew, G.), New York: Wiley, 1996, 3-7. 2. Nighom, A., Hildebrand. J. G.. Dissecting the molecular mechanisms of olfaction in a malaria-vector mosquito, PNAS, 2002, 99(3): 1113-…     

The angiotensin Ⅱ type 1 receptor and receptor-associated proteins

INTRODUCTIONThe renin-angiotensin system (RAS) is consid-ered to be the major regulator of blood pressure)electrolyte balance and renal, neuronal as well as en-docrine functions related to cardiovascular control.The RAS is the key factor in most cases essential hy-pertension, as indicated by successes in treatment ofhypertensive patients with various angiotensin I con-verting enzyme (ACE) inhibitors and receptor block-ers. Renin was a central subject of intense investigation because of…     

《生物多样性》2000年度优秀论文奖

经我刊2/3以上编委投票,并经编委会讨论评选出2000年度优秀论文奖,公布如下： 　　黄宏文,龚俊杰,王圣梅,何子灿,张忠慧,李建强.猕猴桃属(Actinidia)植物的遗传多样性.2000,8(1)1～12 　　东秀珠,沈德龙,辛玉华.16S rDNA同源性所揭示的双歧杆菌与有关细菌的亲缘关系.2000,8（2）146～152 　　王剑伟,王伟,崔迎松.野生和近交稀有鮈鲫的遗传多样性.2000,8（3）241～247 　　本刊将对以上作者颁发荣誉证书、赠送2001年全年刊物并给予一定的物质奖励。 《生物多样性》编辑部     

基于线粒体COI基因的南海浮游介形类斜突浮萤(Proceroecia procera)单倍型与种群遗传结构研究

介形类是一类小型的双壳甲壳类动物, 其海洋浮游种类就超过200余种, 是海洋浮游动物中主要组成部分, 也是海洋生态系统中物质循环与能量流动的关键环节。以线粒体细胞色素氧化酶亚基I(mtCOI)基因为标记, 分析南海浮游介形类中的广布种斜突浮萤(Proceroecia procera)的单倍型多样性与种群遗传结构在空间上的分布, 并结合环境选择压力对种群的遗传多样性与结构分化的影响。结果显示, 38个个体共检出18种单倍型, 广布的单倍型在6个种群中都有分布, 说明P.procera种群可以实现远距离扩散, 最远超过700 km。P.procera种群呈现中度的遗传分化(平均FST = 0.186)。种群间遗传分化系数与地理距离无相关性(r=0.17, p=0.15), 种群未呈现空间距离隔离。远距离分布的单倍型并没有带来强劲的基因流, 相邻种群间甚至呈现出明显的遗传分化。RDA分析结果显示, 空间与环境并不是决定P. procera种群遗传结构的主要因素, 推测历史上种群扩展带来的拓殖隔离可能是主要解释。     

黄河三角洲国家级自然保护区植物区系研究

对黄河三角洲国家级自然保护区的植物区系进行了研究分析,该区系具有以下特点：组成植物区系成分的种类比较少,计有43科,123属,193种,温带性质明显,温带分布型属占总属数的54．7％,植物成分以草本植物为主,自然分布的木本植物只有草麻黄（Ephedra sinica),柳（Salix matsudana),杞柳（S.integra),柽柳（Tamarix chinensis),单叶蔓荆（Vitex trifolia var.simplicifolia)等少数几种,植物成分中盐生物种类比较丰富,计有73种,占总种数的37．8％,植物成分中湿生,水生植物种类丰富,计有92种,占总种数的47．7％,属于比较典型的湿地生态系统。     

The role of nitric oxide in cancer

Nitric oxide (NO) is a pleiotropic regulator, critical to numerous biological processes, including va-sodilatation, neurotransmission and macrophage-mediated immunity. The family of nitric oxide synthases (NOS) comprises inducible NOS (iNOS), endothelial NOS (eNOS), and neuronal NOS (nNOS). Interestingly, various studies have shown that all three isoforms can be involved in promoting or inhibiting the etiology of cancer. NOS activity has been detected in tumour cells of various histogenetic origins and has been associated with tumour grade, proliferation rate and expression of important signaling components associated with cancer development such as the oestrogen receptor. It appears that high levels of NOS expression (for example, generated by activated macrophages) may be cytostatic or cytotoxic for tumor cells, whereas low level activity can have the opposite effect and promote tumour growth. Paradoxically therefore, NO (and related reactive nitrogen species) may have both genotoxic and angiogenic pro