云南高黎贡山地区主要药用蕨类植物

通过对高黎贡山地区的民间访谈和集市药摊调查 ,从高黎贡山地区已纪录的 5 38种蕨类植物中总结、整理出主要的药用蕨类植物 85种 ,分属 2 7科 ,4 4属。本文主要对其中对 17种常见药用蕨类植物的药用功效进行介绍     

闽北地区药用蕨类植物资源

通过对闽北地区的民间访谈和集市药摊调查,从闽北地区已记录的245种蕨类植物中总结、整理出主要药用蕨类植物74种,分属30科,45属.本文主要介绍38种药用蕨类的分布、生活型、药用功效.     

井冈山自然保护区药用蕨类植物资源区系分析

对井冈山自然保护区药用蕨类植物调查研究表明 ,井冈山自然保护区共有药用蕨类植物1 3 4种 (包括变种和变型 ) ,隶属于 3 7科 6 3属 ,占江西药用蕨类植物种数的 6 8.7% ,区系分析显示该地药用蕨类植物区系地理成分复杂 ,具有明显的热带性质和丰富的温带成分 ;药用蕨类植物的生态分布表现出极高的适应性     

南京紫金山4种蕨类植物不同部位总黄酮含量比较

蕨类植物现存约12 000种,以热带、亚热带地区分布最广。中国有蕨类植物61科223属约2 600种,其中可供药用的有300余种,以华南及西南地区分布较多[1]。据报道,药用蕨类植物具有舒筋活血、除湿镇痛、清热滑肠、止咳化痰、利尿安神、止血、驱虫、解毒、抗菌、抗癌和抗HIV等功效[2-7],其化学成分主要包含酚类、黄酮类、生物碱类、甾体及三萜类等化合物,其中黄酮类化合物是蕨类植物中广泛存在的一类成分,     

安徽万佛山药用蕨类植物种类调查

通过对安徽省万佛山自然保护区药用植物资源调查、标本采集鉴定,整理出药用蕨类植物有57种,2变种,隶属23科,37属,并记述它们的生态分布、药用价值,为进一步研究和利用该区药用蕨类植物提供资料。     

浙江北雁荡山野生蕨类植物资源

对浙江北雁荡山的蕨类植物进行专题研究。浙江乐清北雁荡山共有蕨类植物147种,隶属于37科70属。蕨类植物物种密度为42.13/100 km2。比西双版纳的密度1.71/100 km2要高。远大于全国蕨类植物密度0.027/1 000 km2,是我国东南沿海蕨类植物物种密度较高的地区之一。按照用途分为药用、食用、观赏和其他用途4大类型。并记录本地常用蕨类的俗名,统计草药市场药用蕨类资源销售量,为进一步开发利用蕨类植物资源提出建议。     

庐山蕨类植物研究

庐山共有蕨类植物39科87属247 种(含变种),其中药用蕨类植物36科62属121种,观赏蕨类大约102种,土壤指示蕨类植物11科15属25种.区系地理成分复杂,表明成分具有多样性并有热带亲缘性,是亚热带向北温带的过渡地区,是联系中国-日本的桥梁,可能该地区是东亚成分分布中心的一部分.     

庐山蕨类植物研究

庐山共有蕨类植物39科87属247种（含变种），其中药用蕨类植物36科62属121种，观赏蕨类大约102种，土壤指示蕨类植物11科15属25种。区系地理成分复杂，表明成分具有多样性并有热带亲缘性，是亚热带向北温带的过渡地区，是联系中国-日本的桥梁，可能该地区是东亚成分分布中心的一部分。     

福建泉州药用蕨类植物资源调查研究

对泉州市野生蕨类植物的调查表明,该市有药用蕨类植物58种。本文阐述泉州市药用蕨类植物资源区系特征、生态分布、利用价值等,并提出进一步研究及合理开发利用的建议。     

湖北省瓦韦属药用蕨类植物及分布

本文报道湖北省瓦韦属(Lepisorus)药用蕨类植物10种,编写了检索表,并对各种药用瓦韦在本省的分布和主要疗效作了说明。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.