共查询到20条相似文献,搜索用时 46 毫秒
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探讨北京市“医药分开”改革对临床医师用药行为的影响。方法 以北京市试行“医药分开”的部分医院为研究现场,随机抽取800名临床医师进行问卷调查,分析该项改革对临床医师用药行为的影响。结果 临床医师对“医药分开”改革的知晓率为99.5%。“医院宣传”、“专项培训”、“电视广播”为临床医师了解政策的三大主要途径。改革后,92.1%的临床医师更加重视规范诊疗、合理用药;94.4%的临床医师控制大处方,减少开方用药的数量、金额;89.9%临床医师受开药收入、提成、回扣的影响降低。结论 “医药分开”改革对试点医院临床医师的用药行为产生积极影响,规范医师处方行为,加强合理用药,基本实现了改革预期目标。 相似文献
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???? 目的 评价实施手术医师权限管理对手术质量和医疗安全的影响,为手术医师能力评价提供依据。方法 收集新疆某三甲医院实施手术医师权限管理前后同期所有住院由本院医师主刀进行三级及以上非介入手术病例,分析手术级别、主刀医师职称、学历、专业年限与手术并发症发生率的关系。结果 实施手术医师权限管理后,三级及以上手术患者例数同期增长32.66%,手术并发症发生率下降了1.74%,研究生学历组及高年资组的手术并发症发生率明显低于对照组。结论 通过开展手术医师权限管理,有效降低了手术并发症发生率,保障了医疗安全。手术难度、手术医师学历、年资是影响手术并发症发生率的关键因素,单一采用职称与手术操作相对应的技术准入标准存在不合理性。
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In experiments on Black Sea skates (Raja clavata), the potential of the receptor epithelium of the ampullae of Lorenzini and spike activity of single nerve fibers connected to them were investigated during electrical and temperature stimulation. Usually the potential within the canal was between 0 and –2 mV, and the input resistance of the ampulla 250–400 k. Heating of the region of the receptor epithelium was accompanied by a negative wave of potential, an increase in input resistance, and inhibition of spike activity. With worsening of the animal's condition the transepithelial potential became positive (up to +10 mV) but the input resistance of the ampulla during stimulation with a positive current was nonlinear in some cases: a regenerative spike of positive polarity appeared in the channel. During heating, the spike response was sometimes reversed in sign. It is suggested that fluctuations of the transepithelial potential and spike responses to temperature stimulation reflect changes in the potential difference on the basal membrane of the receptor cells, which is described by a relationship of the Nernst's or Goldman's equation type.I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. I. M. Sechenov, Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad. Pacific Institute of Oceanology, Far Eastern Scientific Center, Academy of Sciences of the USSR, Vladivostok. Translated from Neirofiziologiya, Vol. 12, No. 1, pp. 67–74, January–February, 1980. 相似文献
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Birefringence of flow of preparations of myosin 总被引:4,自引:0,他引:4
BINKLEY F 《The Journal of biological chemistry》1948,175(1):385-390
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A sensitive method for the detection of small quantities of hydrophobic antioxidant free radical scavengers such as butylatedhydroxytoluene (BHT) and butylatedhydroxyanisole (BHA) in aqueous samples is described. The procedure involves extraction of the hydrophobic free radical scavenger into an organic solvent phase, followed by the subsequent reaction of an aliquot of this extract with the stable cation radical tris(p-bromophenyl)amminium hexachloroantimonate (TBACA). In experiments with BHT and BHA, the loss of TBACA absorbance at 730 nm was found to be linearly proportional to the amount of antioxidant added, with quantities of BHT as small as 200 pmol being easily detectable. In aqueous suspensions of dimyristoylphosphatidylcholine vesicles, assays of the aqueous BHT concentration showed that BHT partitioned strongly into the membrane phase, achieving very high BHT/phospholipid ratios. For a given concentration of BHT, partitioning into the membrane phase was greater in large, multilamellar liposomes than in either small, single-walled vesicles or in purified rat brain synaptic vesicle membranes. Direct assay of BHT and BHA in phospholipid membranes, however, was complicated by a nonspecific interaction between TBACA and the phospholipid. 相似文献