Paléohistologie et paléobiochimie des vertébrés dans les Annales de Paléontologie

With the exception of one paper published in 1929, works in vertebrate paleohistology start to be published in the journal in 1968 and are published ever since. Similarly, the first paper in vertebrate paleobiochemistry is published in the journal in 1987 and the field is regularly covered ever since. The relatively late publication of paleohistological researches in the journal is all the more surprizing because there are evidences now that several laboratories at the Paris Museum heavily invested in paleohistology already in the 1870–1890th and gathered extensive collections of thin sections, but very few publications followed. The scientific and contextual causes of the late development of the paleohistological publications in the journal are briefly analyzed. It appears that its history is a fairly faithful reflection of several changing scientific and historical constraints which framed not only french paleontology (and notably the “Paris school”) but french biology as well during the XXth century.     

Corrélations entre l'évolution morphologique des membres inférieurs et la récupération fonctionnelle de sujets hémiplégiques

ObjectiveThe aim is to quantify the help provided by recent morphological indicators for hemiplegics patients, after a cerebral vascular accident, during functional rehabilitation. The correlations between functional recovery and the morphological evolution of the muscles and the segments of the lower limb are studied using a MRI system.Material and methodTen adult subjects suffering from vascular hemiplegia have been studied at the ELAN rehabilitation center in Wattrelos. Bobath rehabilitation technique was used to treat patients. Muscular and external volumes of the lower limbs segments, obtained through medical imagery, as well as functional tests (Functional Independence Measure (FIM), Bourges's score and indices of motricity of the pathological limb), were assessed when patients were admitted in and as they left from the rehabilitation centre. Spearman's rho coefficient was used in this study.ResultsThis non-parametric test was considered significant when P < 0.05. It demonstrated a relationship between the evolution of thigh's external and muscular volumes and changes in Bourges's score in seated position (r_s = 0.730 and r_s = 0.764, respectively). It also showed a relationship between pathologic knee motricity index and pathologic leg segment volume evolution (r_s = 0.675).Discussion–conclusionStatistical analysis demonstrated that pathologic thigh volume changes is beneficial to balance during seating as no volume evolution seems to influence balance during standing.     

Cellules souches et biomatériaux injectables pour la médecine régénératrice du cartilage : le consortium « chondrograft »

Articular cartilage is a non innerved, nonvascularized and poorly cellularized connective tissue that is frequently damaged as a result of trauma or age-linked degenerative diseases. It hardly heals spontaneously and its alterations often lead to further extracellular matrix degradation and ultimately, to the loss of joint function. Past decades, many therapeutic approaches have been developed to improve the poor intrinsic self-repair properties of cartilage. Unfortunately, these techniques have not proved really satisfying. In this context, the regeneration of a functional cartilage through tissue engineering and regenerative medicine has recently been contemplated. In particular, the transplantation of autologous reparative cells using a synthetic biomaterial appears promising. We have thus developed and patented a biocompatible self-setting cellulose hydrogel that can be used as an injectable scaffold for cell-based regenerative medicine. Our studies associate this hydrogel with adult mesenchymal stem cells derived from adipose tissue, as a source of reparative cells for cartilage tissue engineering. In a first set of experiments, we have determined the optimal culture conditions required to induce the controlled chondrogenic commitment of stem cells (morphogens, hypoxia, three-dimensional environments…). The preclinical potential of hybrid constructs associating cells and hydrogel has then been assessed with success in animals (mouse, rabbit). Today, trauma and degenerative pathologies of joint tissues remain a major challenge for clinicians and cartilage engineers. Establishing the proof of concept of hydrogel-associated stem cells-based regenerative medicine could help us open new therapeutic windows in the treatment of joint disorders.     

Lésion « pleurale » chez un patient avec antécédent de séminome

We report on the case of a man with a previous history of testicular seminoma and a pathological paravertebral mass definitely taking-up FDG on PET/CT. This mass was finally a benign schwannoma.     

La paléoanthropologie dans les Annales de Paléontologie sous l'impulsion de Marcellin Boule et Jean Piveteau

Because they considered the living world as a unique system, Marcellin Boule and his student, Jean Piveteau, gave an important place in the Annales de Paléontologie to articles dealing with paleoanthropology. With studies about the Man from La Chapelle-aux-Saints by Boule, 1911, Boule, 1912, Boule, 1913) or the skeleton from Regourdou by Piveteau, 1963, Piveteau, 1964, Piveteau, 1966) the Annales de Paléontologie published contributions which are still considered as major articles for knowledge about Neandertals.     

Les Annales de Paléontologie et les Dinosaures

During one century, the “Annales de Paléontologie” have published some articles on the Middle jurassic Dinosaurs from Madagascar, France and Argentina. The review has furnished to their readers' informations on Dinosaurs, which were less known, that the classic faunas from the Upper Jurassic or Upper Cretaceous faunas from North America and Asia. The centenary of the “Annales” give the opportunity to have a look on the discoveries of the past under the light of our modern knowledge.     

Une histoire de géométrie et de finesse (ou : comment parler de phylogénétique ?)

The development of phylogenetic methods since the beginning of the 1970s is analyzed through Armand de Ricqlès’ comment, in 1975, on the triumph of the spirit of geometry over the spirit of finesse. Cladistics was then compared to geometry (Hennig's congruence [i.e. congruent character-state trees]). However, the qualitative aspect of anatomy (spirit of finesse) warrants the quality of a taxon × character matrix so that minimal length trees were never devoid of finesse. Statistical approaches, especially maximum likelihood and Bayesian methods, with sophisticated mathematics (more rigorous geometry?), have reached a wide acceptance after years of debates hindered by polemics. The molecular trees based on these approaches are now dominating the phylogenetic literature, although these trees too include some ambiguity so that one can wonder: do evolutionary models belong to geometry or finesse?     

Le psychothérapeute psychanalyste « à <Emphasis Type="Italic">l’école de la phénoménologie</Emphasis> »

The mixing of psychoanalysis and phenomenology fosters the development of psychotherapy, psychoanalysis drawing on phenomenology to offer a method of studying and understanding the human being; this creates a genuine form of “anthropology”. Phenomenology’s contributions to psychoanalysis revolve around the three notions of épochè, the understanding of others and transference. On the one hand, épochè (a suspension of natural states of mind, obviousness and knowledge; an eidetic reduction; and an opening to the world and others) ensures better comprehension (“to take with yourself”) of others and their existential projects. On the other hand, épochè prevents falling into the transference and countertransference traps and sets the distance necessary for the hermeneutic act, that is, the interpretation of what is no longer there, what is absent, yet said and indicated by language in psychoanalytic therapy. Through its humanist, anthropological perspective and its overall understanding of the human being, phenomenology leads the way to rethinking clinical psychotherapy to create a more unified discipline.     

Activité cytokinine de dérivés acylés,alkylés,acyl-alkylés de l'adénine et d'isost`eres azotés de la γ,γ-diméthylallyladénine

The cytokinin activities of various 6-acylaminopurines, 6-alkylaminopurines, 6-acylamino-9-benzyl-purines as well as a series of isosteric-nitrogen derivatives of N⁶-(γ, γ-dimethylallyl)adenine (I⁶Ade) have been tested using the tobacco pith and the pea bud bioassays. The interactions between active, slightly active and inactive compounds have been studied with the last assay. Acylation decreases the biological activity; e.g., N⁶-benzoyl and N⁶-furoyladenines are less active than Na⁶-benzyladenine and kinetin. Substitution at the 9-position reduces (tobacco-pith assay) or suppresses (pea-bud assay) the phytohormonal activity of otherwise active 6-acylaminopurines. In isosteric derivatives, maximum activity occurs when the side chain has the same length as in 1⁶Ade. After the analysis of interactions between more or less active compounds, it is suggested that the differences in cytokinin activity could be related to unequal affinities for a hypothetical receptor site.     

Existe-t-il un Paléolithique inférieur au Japon ?

All Lower Paleolithic sites discovered by Mr. Shinïchi FUJIMURA from 1981 to 2000 were falsified by himself. We wonder if Lower Paleolithic sites really exist (corresponding to a period of 30,000 years ago in Japan) in the archipelago of Japan. We examined cultures of sites likely dating to the Early Upper Paleolithic and Lower Paleolithic discovered in the archipelago of Japan. While Japan was continuous with the continent in the Mindel glaciation (400,000 years ago) or in the Riss glaciation (200,000 years ago), Homo erectus or Homo heidelbergensis with the lithic industry of the Acheulean arrived in the archipelago of Japan. Thereafter, they survived on the islands of Japan cut the continent to the Upper Paleolithic while keeping the industry.     

L’évolution des premiers arbres : les stratégies dévoniennes

The earliest axes exceeding 10 cm in diameter, and presumed to represent small trees, evolved in the Middle Devonian (about 395 million years). They belong to the Cladoxylopsida, a basal group of ferns s.l. lacking leaves. These trees grow mainly vertically, the trunk producing short-lived branches at the top and adventitious roots at the base. They show a dissected vascularisation, and little if any secondary tissues. The Archaeopteridales that evolved at the end of the Middle Devonian, have leaves, abundant wood, and secondary phloem. Growth in the aerial and subterranean parts is tri-dimensional and extensive. Contrary to these two strategies that evolved several times independently during the history of terrestrial plants, that exhibited by the lycophytes became extinct at the end of the Mesozoic. These trees are characterized by a symmetrical development of the aerial and underground parts that branch dichotomously. Branch production by the trunk is relatively late. These trees show a narrow vascular system and a wide cortex.     

Purification de l'alcool deshydrogénase de tomate par chromatographie d'affinité

Tomato alcohol dehydrogenase has been purified 99-fold by affinity chromatography on Blue Sepharose CL-6B with 37% yield. The enzyme so obtained is homogenous in polyacrylamide gel electrophoresis. By adding 20% glycerol to the extraction and purification buffers, an enzyme is obtained which is stable for several months at 4°. The molecular weight values determined by gel filtration (Sephadex G 200) and polyacrylamide gradient gel electrophoresis on one hand and by polyacrylamide gel electrophoresis in sodium dodecyl sulfate on the other, show that the enzyme exists in dimeric form.     

Simulation d'un plan d'expérience en océanographie: Effets de la dispersion des organismes sur l'erreur d'échantillonnage

Seven spatial dispersions of organisms, reflecting some constraints of various physical and biological factors of the pelagic environment were simulated on computer. The relationships between the sampling methods (tow length, net size), the pelagic population dispersion patterns, and the sampling error were investigated by computer simulation. Two categories of dispersions were identified: 1) random or relatively uniform dispersions of organisms (including Poisson, gradient, and negative contagous dispersions), characterized by an index of dispersion $\text{s}{}^2\text{m}\text{< 1.5}$; and 2) overdispersed distributions of swarming or clustering organisms (including positive contagion and centric aggregation dispersions), characterized by a value of $\text{s}{}^2\text{m}\text{> 1.5}$.The origin and size of the sampling errors as deduced from the analysis of variance change, considerably from one group of dispersions to the other. In the first case, the net size was dominant, whereas in the second case the tow length and patch size effects are more critical. In general, the precision of estimations decreases as the over-dispersion of organisms increases. The confidence limits, for a simple estimation of abundance, vary considerably with the spatial dispersion, ranging from narrow values for the relatively uniform dispersions to very large values for the overdispersed distributions. There is an increasing imprecision in the estimate of population abundance as the dispersion coefficient $\text{s}{}^2\text{m}$ increases.Analysis of coefficients of variation indicates that more precise estimates of abundance may be obtained if a practical sampling procedure is applied to a group of specific organisms. Furthermore, it is suggested that a simulated approach, performed prior to ocean sampling, permits the establishment of the optimal sampling procedure for the species under study.     

Modalités d'installation et d'évolutiondes Harpocératinés (ammonitina A) au Domérien inférieur dans le sud-Ouest de l'Europe (France,Portugal)

In Mesogea, the Harpoceratinae were known asearly as the end of the Lower Carixian. They later reached the sub-boreal province through the Alps or the South of the Iberic Peninsula. The analysis of the populations met in four crosssections of the Lower Domerian (Causses, Mâconnais, Franche-Comté, Portugal) showed the settling down of the Protogrammoceras isseli group that set up and evoluated in a similar way in the different areas in spite of a certain originality.On the one hand, it gave the cladogenetic groupP. monestieri-nitescens by diminution of the ribing density, strengthening of the ribs and simplification of the suture.On the other hand, a slower evolution give, near the end of the Stokesi zone, P. normanianum in the Paris Basin and in Burgundy, and P. lusitanicum in Portugal. At the same time, a new invader, P. celebratum, arrived in the Causses (and in Portugal).     

Évolution « graduelle » à l’échelle géologique chez les rongeurs fossiles du Cénozoïque européen

Cases of gradualism in rodent evolution during the Cainozoic in Europe. Since several decades, conflicting interpretations of the fossil record are well known when the latter is used to understand mechanisms and modes of biological evolution. Once recalled peculiarities of the paleontological material and approach, several cases studies conducted by teams of the laboratory of Montpellier are presented. It clearly appears that Theridomyidae, Gliridae and Murinae rodents illustrate gradual evolution at the geological time scale. At the same time scale, these groups do not give obvious examples of stasis. The understanding in terms of mechanisms of morphological evolution illustrated by fossils will remain a long running debate. And this despite consideration of the time scales involved in Earth History on the one hand, and in Biology and Ecology on the other hand, as well as of the gap between morphological change in individuals and genetic change within populations. To cite this article: M. Vianey-Liaud, J. Michaux, C. R. Palevol 2 (2003).     

Quand le renne entra au panthéon du Paléolithique supérieur ?

By means of critical analysis of style of reindeers figures calling on graphic detailed conventions and on their associations with a cattle into that species of very rigorous climate prevail over the others, such musk-beef, glutton and saïga, but also plenty of bison's, as well as horses, it appears hardly likely, to do not say impossible, that reindeers of Chauvet's cave can have aurignacian origin. That all the more as they would be all alone in this case among one hundred sixty-six taking the census of representation. Their comparison with the other reindeers of the different sites generally do not distinguish from solutrian or Magdalenian reindeers and bring together particularly with Gabillou by many stylistic concurrents. If A. Leroi-Gourhan has already established that link between horse and reindeer only appears at Magdalenian, it seems now that it is possible to extend to superior Solutrian in support of representations of our inventory, reflecting climate aggravation that takes place at this moment and promotes plenty of two species in the neighbourhood.