珍稀濒危植物青钩栲种群数量特征研究

提出自适应种群增长新模型Ｓ＝ｅｘｐ（ａｌｎ＾２（１＋ｃｅ＾－ｒｔ）＋βｌｎ（１＋ｃｅ＾－ｅｔ）＋γ）,该模型包融了Ｌｏｇｉｓｔｉｃ模型、Ｓｍｉｔｈ模型、Ｇｏｍｐｅｒｔｚ模型、崔－Ｌａｗｓｏｎ模型、张－Ｌｏｇｉｓｔｉｃ模型和刘－Ｌｏｇｉｓｔｉｃ模型,运用遗传算法适应新模型进行参数估计,拟合青钩栲种群增长规律比其它种群增长模型更符合青钩栲群种的实际增长趋势,说明新模型具有一定的实用价值。     

格氏栲种群生态学研究 Ⅲ. 格氏栲种群优势度增长动态规律研究

采用有限空间种群增长的逻辑斯谛模型探讨格氏栲种群基面积增长规律。提出自适应通用模型ds/dt=rs(1-s^θ/k^φ).该模型包括Logistic模型、Smith模型、Gompertz模型、崔Lawson模型和Z-Logistic模型;运用改进单纯形对自适应通用模型进行优化,拟合结果比Logistic模型更符合格氏栲种群实际增长趋势,增长速度最大是在147年。     

格氏栲种群优势度增长改进模型的研究

提出有限的空间种群增长的Logistic改进模型探讨格氏栲种群基面积增长规律,即dS/dt=rS(1-S^θ/K）。该模型通过树种的竞争特性因子θ控制,将指数增长、线性制约、下凹增长和上凸增长非线性制约概括一个统一的自适应性的非线性制约通用模型。运用改进单纯形对Logistic改进模型进行优化,拟合结果表明改进模型是格氏栲种群优势度增长动态变化的一个极好机理描述式,其增长速度最大是在141年。     

格氏栲种群调节模型的研究

在前人对植物种群自然稀疏过程的研究基础上,结合自适应通用增长模型,推导出一种能描述密度变化全过程的理论模型,ｌｎＮ＝ａｌｎ＾２Ｓ＋ｂｌｎＳ＋ｃ,其中Ｎ和Ｓ分别为种群密度和单株基面积,ａ、ｂ、ｃ为参数。     

运用改进单纯形法拟合Logistic曲线的研究

Ｌｏｇｉｓｔｉｃ方程是研究有限空间内种群增长规律的重要工具之一本文运用改进单纯形法最优拟合Ｌｏｇｉｓｔｉｃ曲线,结果表明改进单纯形法具有较强的拟合非线性方程的能力,对生物实验及生态、生理学中诸多非线性曲线的参数估计具有普遍意义．     

松突圆蚧种群动态研究

对松突圆蚧为害时间不同的两个调查区的松突圆蚧种群动态进行调查,建立了相应的数学模型．对松突圆蚧种群的全年种群波动规律运用带时滞效应的Ｌｏｇｉｓｔｉｃ模型进行拟合,通过内禀增长率ｒ和时滞τ的拟合值对种群出现的周期性波动作出解释．     

带扩散的Logistic单种群模型及其最优收获

在一些合理的假设条件下,就空间分布非均匀的Ｌｏｇｉｓｔｉｃ型收获模型 得到了与空间分布均匀的Ｌｏｇｉｓｔｉｃ型收获模型［１,２,３］完全平行的结论,其中包括种群持续生存和灭绝时收获努力量 Ｅ（ｘ）须满足的充要条件、种群持续生存时趋于正平衡状态的速度估计、种群灭绝时其密度趋于０的速度估计以及在种群持续生存条件下的最优收获努力量 Ｅ、最优平衡解 ｐ（ｘ）和最大收获量 ｈ＊     

一类具周期系数的单种群模型及其最优收获策略

文［１］用直接求解的方法,得到了具周期系数的广义Ｌｏｇｉｓｔｉｃ单种群收获模型的最优收获策略．本文在参照并推广文［２］中一类具周期系数的单种群收获模型周期解的全局渐近稳定性结果的基础上,用变分方法得到了其最优收获策略．所得结果包括了许多常见的自治单种群模型所对应的具周期系数的收获模型,如Ｌｏｇｉｓｔｉｃ型［１］,Ｇｉｌｐｉｎ和Ａｙａｌａ型, Ｇｏｍｐｅｒｔｚ型［３］,以及具类似于Ⅱ,Ⅲ类Ｈｏｌｌｉｎｇ型功能性反应的密度制约函数［４,５］的模型等．     

格氏栲种群数量动态的谱分析研究

运用谱分析数学方法,研究分析格氏栲林格氏栲种群动态规律．结果表明：格氏栲种群数量动态的周期波动性是明显的,与格氏栲天然更新过程有关;不同生境、人为干扰均对辂氏栲种群数量动态的波动产生影响;格氏栲生长量的周期波动与其种群数量动态的周期波动特征基本一致,表明格氏栲种群数量动态呈周期波浪式发展,即表征格氏栲林优势种群的稳定性。     

格氏栲种群个体年龄与胸径的时间序列模型研究

本文提出格氏栲种群以年轮确定种群个体年龄并与胸径、树高确定种群个体年龄有机结合的时间序列预测个体年龄方法。通过时间序列分析,确定出格氏栲种群个体年龄与胸径关系的ＡＲＩＭＡ（１,２,０）模型,经检验该模型的相似性系数为９３．４８％,即该模型预测胸径生长量是可靠的。同时,通过ＡＲＩ－ＭＡ（１,２,０）模型预测结果与实际调查材料组合起来,建立较为准确反映个体年龄的组合模型：Ａ＝１０．１５４５１＋１．１１３８５１Ｄ＋０．０４２２００４９Ｄ２－０．０００２２７３０３Ｄ３式中Ｄ为格氏栲种群个体胸径,Ａ为格氏栲种群个体年龄,相关指数为０．９９９８。可见,组合模型的格氏栲种群个体胸径与年龄回归关系极显著,效果理想,为相应研究提供一个较为可靠的方法。     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

Highlights
1. The N-terminal tail of histone H3 is specifically cleaved during EV71 infection.
2. Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail.
3. Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.     

Detection of EBV and HHV6 in the Brain Tissue of Patients with Rasmussen’s Encephalitis

Rasmussen’s encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human herpes virus (HHV) 6 antigens in brain sections from 30 patients with RE and 16 control individuals by immunohistochemistry. In the RE group, EBV and HHV6 antigens were detected in 56.7% (17/30) and 50% (15/30) of individuals, respectively. In contrast, no detectable EBV and HHV6 antigen expression was found in brain tissues of the control group. The co-expression of EBV and HHV6 was detected in 20.0% (6/30) of individuals. In particular, a 4-year-old boy had a typical clinical course, including a medical history of viral encephalitis, intractable epilepsy, and hemispheric atrophy. The co-expression of EBV and HHV6 was detected in neurons and astrocytes in the brain tissue, accompanied by a high frequency of CD8⁺ T cells. Our results suggest that EBV and HHV6 infection and the activation of CD8⁺ T cells are involved in the pathogenesis of RE.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.