福建省主要木本药用植物资源

介绍了福建省分布或栽培的木本药用植物种类,并着重介绍了24种常用中药材(植物种类30种)的分布及药用功效.木本药用植物的保护和栽培既是医药工业的需要,也是福建省建设生态农业、生态林业和生态旅游业的重要内容.建议重视木本药用植物的研究与开发,建立更多的木本药用植物生产与研究基地.     

江苏省主要木本药用植物资源

概述了江苏省有分布或栽培的木本药用植物资源,其中对主要种类20种的分布及药用功效进行了详细介绍,对其他木本药用植物的分布进行了简单的概述。近年来,越来越多的药用木本植物成为国内外研究者研究的重点对象。建议本省中医药工作者重视木本药用植物的药用价值的研究与开发。     

贵州省楠杆自然保护区药用植物多样性调查

贵州德江楠杆自然保护区药用植物资源种类丰富,首次调查植物种类达2 000余种,查阅药用植物文献资料记载,鉴定有药用植物1 079种,隶属于201科603属。其中,真菌类植物19科23属35种,苔藓类14科14属16种,石松和蕨类植物19科42属88种,裸子植物7科11属14种,双子叶植物121科426属792种,单子叶植物21科87属134种,草本多达587种,木本多达438种。对该地区药用植物的组成、丰富度与周边地区进行了比较,提出了保护利用及可持续发展的建议。     

药用植物多样性特征分析——以陕北米脂县为例

为研究陕北米脂县野生药用植物资源现状及其分布规律,通过野外调查及查阅文献等方法,对该地区药用植物多样性及其特征进行研究。结果显示：（1）米脂县共有野生药用植物45科110属148种,其中裸子植物2科2属2种、被子植物43科108属146种,集中分布于单种科和寡种科及单种属内;（2）从生长型来看,草本植物最多,其次是乔木,灌木最少;（3）药用部位以全草类、根及根茎类最多,分别占药用植物总种数的52.03%和14.86%;（4）药用功效以清热和利水渗湿为主,分别占药用植物总数的23.65%和11.49%;（5）从药用植物属的分布类型来看,有13个分布区类型8个变型,区系成分复杂多样,温带性质明显。本研究表明米脂县药用植物资源多样性较高,生长型、药用部位、功效、区系成分丰富多样,明确了该地区野生药用植物资源的分布及生存现状,为加强资源的保护及开发利用提供了依据。     

福建尤溪枕头山森林公园野生唇形科药用植物资源调查及其开发利用

福建省尤溪县枕头山森林公园野生唇形科药用植物资源丰富,共有药用植物14属24种（包括变种、变型）。在查清资源种类的基础上,对该区野生唇形科药用植物的优势属、入药部位、生活型、生态环境、数量与分布、利用情况以及开发利用途径进行分析,同时提出保护与开发利用措施和建议。     

福建省永春县木本药用植物资源调查

永春县地处中亚热带和南亚热带的过渡区域,自然条件优越,木本药用植物资源丰富。通过野外实地考察、标本采集、资料查阅整理及标本鉴定,初步查明,永春县境内有木本药用植物45科90属129种(含变种)。对其药用部位和功用作了简要介绍,对本地药用植物资源的保护和开发利用提出建议。     

陕西留坝地区种子植物区系分析

陕西留坝地区有种子植物１３３科、６３５属、１４８０种。本文对该地区植物区系进行了统计分析。统计分析结果表明：（１）本地区种子植物种类丰富,共有裸子植物６科、１３属、１９种;单子叶植物１８科、１３５属、２９７种;双子叶植物有１０９科、４８７属、１１６４种。木本种类５６６种,占３８．２％,草本９１４种,占６１．８％。（２）属的地理分布类型种类多,１５个分布类型及１５个变型。其中温带成分占６７．０％,有     

福建被子植物分布新记录Ⅰ

在福建省药用植物资源调查中,陆续发现了福建省被子植物地理新分布记录属及种多个,经整理鉴定,本文报道新分布记录属：八宝属（Hylotelephium）、假奓包叶属（Discocleidion）;新分布记录种：浙江蜡梅（Chimonanthus zhejiangensis）、柳叶蜡梅（Chimonanthus salicifolius）、紫花八宝（Hylotelephium mingjinianum）、冷饭藤（Kadsura oblongifolia）、假奓包叶（Discocleidion rufescens）。凭证标本暂存于福建中医药大学药用植物标本室。     

思茅地区国家重点保护野生药用植物资源研究

报道思茅地区国家级重点保护的20种野生（栽培）药用植物资源（一级2种、二级13种、三级5种）。其中，绝大部分种类在思茅地区傣族、拉祜族、彝族聚居地区有分布，并为常用药。并介绍其入药部位、功能、分布、国家保护级别、保护价值。同时提出对资源进行开发和利用的建议。     

陕西省永寿县药用植物资源调查分析

依托第四次全国中药资源普查，采用野外踏查、样线调查和样方调查的方法对陕西省永寿县药用植物资源进行调查与分析；查清永寿县药用植物资源分布情况，为该县药用植物资源保护、开发利用提供科学依据。结果表明，永寿县现有药用植物276种，隶属79科222属，科组成以菊科、豆科为优势科，分别包含36种和22种药用植物；草本植物为永寿县药用植物的主要类型，占总数的72.83%；野生重点调查药用植物65种，隶属35科61属，其中以根及根茎类入药的药用植物占比为最高（46.15%）；同时，调查还发现了甘草（Glycyrrhiza uralensis Fisch.）、杜鹃兰[Cremastra appendiculata (D. Don) Makino]等10种珍稀濒危药用植物。综上所述，永寿县药用植物资源种类丰富、耐旱喜阳药用植物居多、中药资源开发利用前景广阔。通过本次中药资源普查，基本摸清了永寿县中药资源家底，可为当地中药产业的可持续发展提供参考。     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

鸡传染性法氏囊病病毒研究进展

传染性法氏囊病(Infection bursal disease, IBD)是由鸡传染性法氏囊病毒(Infectious bursal disease virus, IBDV)引起的鸡和火鸡的一种高度接触性传染病,给世界各国的禽养殖业带来了巨大损失.自IBDV发现至今新的变异株不断出现,分子结构的改变导致病毒致病力的改变及宿主对疫苗应答的改变,使得传统的疫苗已不能控制其流行,因此各国学者对其基因组结构和功能进行了广泛深入的研究,并积极研制新型有效的疫苗以达到防治的目的.     

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

In conclusion, the novel visual RT-LAMP assay is a simple, rapid, and sensitive approach for detection of SARS-CoV-2, and it is ready for application in primary care and community hospitals or health care centers, and even patients' own houses in response to the current SARS-CoV-2 epidemic because the assay does not require sophisticated equipment and skilled personnel. Furthermore, it is also ready to be used in fields for screening samples from wild animals and environments to facilitate the identification of potential intermediate hosts that mediate the cross-species transmission of SARS-CoV-2 from bats to humans.     

Perinatal Vertical Transmission of Chikungunya Virus in Ruili,a Town on the Border between China and Myanmar

正Dear Editor,Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A.aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019). It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. However, in the epidemic in 2004, CHIKV acquired mutations that conferred enhanced transmission by the A. albopictus mosquito(Schuffenecker et al. 2006). Since then, it has successively caused outbreaks in Africa, the Indian Ocean, South East Asia, the South America, and Europe (Zeller et al. 2016).