共查询到20条相似文献,搜索用时 15 毫秒
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von Blume J Alleaume AM Cantero-Recasens G Curwin A Carreras-Sureda A Zimmermann T van Galen J Wakana Y Valverde MA Malhotra V 《Developmental cell》2011,20(5):652-662
Highlights? ADF/cofilin localizes to the TGN and binds SPCA1 in an actin-dependent manner ? Dynamic actin regulates the activity of the Ca2+ pump SPCA1 ? ADF/cofilin facilitates secretory cargo sorting in a Ca2+-dependent manner 相似文献
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Rebecca A. Oot Li-Shar Huang Edward A. Berry Stephan Wilkens 《Structure (London, England : 1993)》2012,20(11):1881-1892
Highlights? Two conformations of yeast V-ATPase EGChead peripheral stalk complex were solved ? The EG heterodimer of the eukaryotic V-ATPase forms a noncanonical coiled coil ? Subunit G contains a conserved random coiled bulge that interrupts the coiled coil ? The EGChead interaction represents an important target for therapeutic development 相似文献
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Aaron Ehlinger Soyeon Park Amr Fahmy Jeffrey W. Lary James L. Cole Daniel Finley Kylie J. Walters 《Structure (London, England : 1993)》2013,21(5):753-765
Highlights? Proteasome ATPase Rpt6 undergoes helix-coil exchange in its C-terminal domain ? Rpt6 G360,387A has a stabilized four-helix bundle and raised melting temperature ? Assembly chaperone Rpn14 binds selectively to the four-helix bundle Rpt6 conformer ? Rpt6 G360,387A (rpt6AA) is synthetically defective with an rpn14 null mutation 相似文献
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