中国灰蝶科一新属一新种：鳞翅目：灰蝶科

中国灰蝶科一新属一新种（鳞翅目：灰蝶科）周尧,王敏（西北农业大学昆虫研究所陕西省杨陵区７１２１００）本文记述我国灰蝶科１新属１新种,即秦灰蝶属ＱｉｎｏｒａＰａｌａｇｅｎ．ｎ．及其模式种秦灰蝶Ｑｉｎｏｒａｐａｌａａｉｎｌｉｎｍｎａｓｎｎ。新属与燕灰蝶属...     

江西玉山王家坝早志留世早期(Early Llandoverian)新腕足动物群的发现及其意义

系统描述江西省玉山县王家坝地区早志留世早期（ＥａｒｌｙＬｌａｎｄｏｖｅｒｉａｎ）地层中新发现的腕足动物群６目、９超科、１７科（其中１新科）、２１属（其中１新属）、２８种（其中７新种、１相似种、６未定种）,并将它们统称为ＩｓｏｒｔｈｉｓＬｅｐｔａｅｎａ动物群。同时指出发现该腕足动物群的意义及其生存的地质时代。     

马蝉属一新种和二中国新记录种：同翅目：蝉科

马蝉属一新种和二中国新记录种（同翅目：蝉科）雷仲仁,李莉（西北农业大学昆虫研究所,陕西省杨陵区７１２１００）关键词同翅目,蝉科,马蝉属,分类学本文记述马蝉属１新种和２中国新记录种。模式标本保存在中国科学院上海昆虫研究所。１．平片马蝉Ｐｌａｔｙｌｏｍｉ...     

新疆蝗虫一新属一新种（直翅目：网翅蝗科）

本文记述采自中国新疆的网翅蝗科１新属：拟草地蝗属及１新种：新疆拟草地蝗。模式标本保存于陕西师范大学动物研究所。     

金小蜂科一新属(膜翅目:小蜂总科)

本文记述了我国金小蜂科、寡金小蜂亚科的１新属和１新种。模式标本存于中国科学院动物研究所动物标本馆。     

琅琊山蝶类资源调查初报

在安徽省滁州市琅琊山国家级森林公园采集到凤蝶科蝴蝶５属１０种、蛱蝶科１２属１７种、粉蝶科３属５种、眼蝶科３属４种、灰蝶科１０属１２种、喙蝶科１属１种、弄蝶科３属４种。其中,１种为我国特有珍稀蝶类,３１种为安徽省新记录,并记录各种蝴蝶的学名,寄主和区系组成。     

新疆网翅蝗科一新属一新种（直翅目：蝗总科）

本文记述了采自中国新疆的网翅蝗科１新属：短翅蝗属及１新种：尼勒克短翅蝗。模式标本存于陕西师范大学动物研究所蝗虫标本室。     

云南蕨类植物小志

根据ＰＹＵ（云南大学蕨类植物标本室）保存的标本,报道云南蕨类植物若干新资料,内容为：３新种,２新变种,中国分布新记录２种,云南分布新记录１属３种,１个种的新组合名称,另１个种的属、科位置的订正及其新组合名称。     

中国大叶蝉科一新记录属及一新种一新组合（同翅目：叶蝉总科）

记述大叶科１中国新记录属－长冠叶蝉属Ｓｔｅｎａｔｋｉｎａ Ｙｏｕｎｇ及１新种－双斑长冠叶蝉Ｓｔｅｎａｔｋｉｎａ ｂｉｍａｃｕｌａｔａ,ｓｐ,ｎｏｖ．和１新种组合－角突长冠叶蝉Ｓｔｅｎａｔｋｉｎａ ａｎｇｕｓｔａｔａ,ｃｏｍｂ,ｎｏｖ．模式标本保存在贵州大学昆虫研究所。     

吉林浑江地区早奥陶世亮甲山组的大型短粗壳内角石类

对产自吉林浑江大阳贫早奥陶世亮甲山组的大型粗壳内角石类进行系统进行,共描述２科３属３７种和１个科属未定标本,其中１新属、３新种和２未定种。首次报道Ｐｉｌｏｃｅｒａｔｉｄａｅ科分子（Ｐａｒａｃａｓｓｉｎｏｃｅｒａｓ ｄａｙａｎｇｃｈａｅｎｓｅ ｇｅｎ．ｅｔ ｓｐ．ｎｏｖ．）在东亚的首次发现。提出角石类内体管构造的４个类型。详细讨论Ｍａｎｃｈｕｒｏｃｅｒａｓ和Ｍａｎｃｈｕｒｃｅｒａｉｄａｅ科的地理分布     

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus(KSHV; also known as human herpesvirus 8(HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Microbial resistance to antibiotics is an unresolved global concern, which needs urgent and coordinated action. One of the guidelines of the Centers for Disease Control and Preventions (CDC) to combat antibiotic resistance is the development of new antibiotics to treat drug-resistant bacteria. In our effort to find new antibiotics, we report the synthesis and antimicrobial studies of 30 new pyrazole derivatives. These novel molecules have been synthesized by using readily available starting materials and benign reaction conditions. Some of these molecules have shown activity with MIC values as low as 0.78?µg/mL against four bacterial strains; Staphylococcus aureus, methicillin-resistant S. aureus, Bacillus subtilis, and Acinetobacter baumannii. Furthermore, active molecules are non-toxic to mammalian cell line.

     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.     

Novel compounds with potent CDK9 inhibitory activity for the treatment of myeloma

Cyclin-dependent kinases (CDKs) and Polo-like kinases (PLKs) play key role in the regulation of the cell cycle. The aim of our study was originally the further development of our recently discovered polo-like kinase 1 (PLK1) inhibitors. A series of new 2,4-disubstituted pyrimidine derivatives were synthesized around the original hit, but their PLK1 inhibitory activity was very poor. However the novel compounds showed nanomolar CDK9 inhibitory activity and very good antiproliferative effect on multiple myeloma cell lines (RPMI-8226).