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Langmade SJ Ravindra R Daniels PJ Andrews GK 《The Journal of biological chemistry》2000,275(44):34803-34809
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C. elegans metallothioneins: new insights into the phenotypic effects of cadmium toxicosis 总被引：11，自引：0，他引：11
Swain SC Keusekotten K Baumeister R Stürzenbaum SR 《Journal of molecular biology》2004,341(4):951-959
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The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development 
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下载免费PDF全文 Andrews GK Lee DK Ravindra R Lichtlen P Sirito M Sawadogo M Schaffner W 《The EMBO journal》2001,20(5):1114-1122
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Two forms of hepatic metallothionein were isolated and purified from rainbow trout injected intraperitoneally with cadmium chloride. Both forms showed similarities with mammalian metallothioneins, had a high cystein content (30 mol%), and were void of aromatic amino acids and histidine. The molecular weight was estimated to be about 6000 dalton for the apothioneins, and the thiol groups of the cysteine residues complexed with the heavy metals (Cd, Cu, Zn) in a SH/Me++ ratio of about 2.4. The amount of copper in metallothionein from rainbow trout was very high, greater than the amount of cadmium and zinc after injections of 3 mg cadmium/kg body weight. The total metal content of cadmium, copper and zinc in metallothionein 1 and 2 were about 7 and 8 atoms per molecule respectively. 相似文献
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