Animal Protection Measures in Taiwan: Taiwanese Attitudes Toward the Animal Protection Law and Animal Shelters

This study used a questionnaire, self-administered by 387 Taiwanese citizens, to assess Taiwanese perception and knowledge of the Animal Protection Law and perception and use of animal shelters. Most respondents (87%) knew that Taiwan has legal protection for animals. A –5 to 5 summary score measured knowledge of companion animal dog-related legal requirements. The median score was 3, indicating that almost all respondents had inadequate knowledge about these requirements. Although more dog caregivers had adequate knowledge of the law than did nondog caregivers (prevalence ratio = 1.9, 95% confidence interval: 1.1, 3.2), only 19% had adequate knowledge. Although most respondents (81%) knew Taiwan has animal shelters, only 19 (5%) reported visiting or participating in shelter activities. Only 6 (32%) of shelter visitors or users had a "good or better" impression of services received. Despite low usage of animal shelters, most respondents thought shelters should accept (87%) and relocate (90%) unwanted animals, capture strays (64%), assist in finding lost pets (79%), and educate the public about responsible ownership (85%). More than half (52%) thought shelters should perform euthanasia.     

Animal protection measures in Taiwan: Taiwanese attitudes toward the animal protection law and animal shelters

This study used a questionnaire, self-administered by 387 Taiwanese citizens, to assess Taiwanese perception and knowledge of the Animal Protection Law and perception and use of animal shelters. Most respondents (87%) knew that Taiwan has legal protection for animals. A -5 to 5 summary score measured knowledge of companion animal dog-related legal requirements. The median score was 3, indicating that almost all respondents had inadequate knowledge about these requirements. Although more dog caregivers had adequate knowledge of the law than did nondog caregivers (prevalence ratio = 1.9, 95% confidence interval: 1.1, 3.2), only 19% had adequate knowledge. Although most respondents (81%) knew Taiwan has animal shelters, only 19 (5%) reported visiting or participating in shelter activities. Only 6 (32%) of shelter visitors or users had a “good or better ”impression of services received. Despite low usage of animal shelters, most respondents thought shelters should accept (87%) and relocate (90%) unwanted animals, capture strays (64%), assist in finding lost pets (79%), and educate the public about responsible ownership (85%). More than half (52%) thought shelters should perform euthanasia.     

An analysis of the possible effects of the 2001 foot and mouth disease epidemic on grass pollen concentrations in the Midlands, UK

The 2001 grass pollen season in the United Kingdom was notably severe. An epidemic of foot and mouth disease (FMD) occurred in the UK during February and spread through the country during the summer. The media claimed that the control measures of culling infected animals and the restricted movement of stock, led to reduced grazing allowing pastures to flower more than in previous years. This study aimed to examine whether the severity was due only to weather factors or if the control measures also contributed. Three pollen sites from the FMD-affected Midlands region were investigated and compared with two sites from regions unaffected for differences in pollen catches, culling levels and weather. The June pollen catch in the Midlands was particularly high but this pattern also features in areas such as Cambridge in the East that were minimally affected by the epidemic. In most of the catchment areas affected by FMD the quantity of animals culled was less than 10% of the total livestock. In areas where culling was concentrated we can assume that there would have been some localized affect on the pollen levels. The results show that the main influencing variable on the 2001 grass pollen counts in the Midlands was the weather and that culling due to the foot and mouth epidemic did not exert an important influence at the regional level.     

An analysis of the possible effects of the 2001 foot and mouth disease epidemic on grass pollen concentrations in the Midlands, UK

The 2001 grass pollen season in the United Kingdom was notably severe. An epidemic of foot and mouth disease (FMD) occurred in the UK during February and spread through the country during the summer. The media claimed that the control measures of culling infected animals and the restricted movement of stock, led to reduced grazing allowing pastures to flower more than in previous years. This study aimed to examine whether the severity was due only to weather factors or if the control measures also contributed. Three pollen sites from the FMD-affected Midlands region were investigated and compared with two sites from regions unaffected for differences in pollen catches, culling levels and weather. The June pollen catch in the Midlands was particularly high but this pattern also features in areas such as Cambridge in the East that were minimally affected by the epidemic. In most of the catchment areas affected by FMD the quantity of animals culled was less than 10% of the total livestock. In areas where culling was concentrated we can assume that there would have been some localized affect on the pollen levels. The results show that the main influencing variable on the 2001 grass pollen counts in the Midlands was the weather and that culling due to the foot and mouth epidemic did not exert an important influence at the regional level.     

An analysis of the possible effects of the 2001 foot and mouth disease epidemic on grass pollen concentrations in the Midlands,UK

The 2001 grass pollen season in the United Kingdom was notably severe. An epidemic of foot and mouth disease (FMD) occurred in the UK during February and spread through the country during the summer. The media claimed that the control measures of culling infected animals and the restricted movement of stock, led to reduced grazing allowing pastures to flower more than in previous years. This study aimed to examine whether the severity was due only to weather factors or if the control measures also contributed. Three pollen sites from the FMD-affected Midlands region were investigated and compared with two sites from regions unaffected for differences in pollen catches, culling levels and weather. The June pollen catch in the Midlands was particularly high but this pattern also features in areas such as Cambridge in the East that were minimally affected by the epidemic. In most of the catchment areas affected by FMD the quantity of animals culled was less than 10% of the total livestock. In areas where culling was concentrated we can assume that there would have been some localized affect on the pollen levels. The results show that the main influencing variable on the 2001 grass pollen counts in the Midlands was the weather and that culling due to the foot and mouth epidemic did not exert an important influence at the regional level.     

The role of pre-emptive culling in the control of foot-and-mouth disease

The 2001 foot-and-mouth disease epidemic was controlled by culling of infectious premises and pre-emptive culling intended to limit the spread of disease. Of the control strategies adopted, routine culling of farms that were contiguous to infected premises caused the most controversy. Here we perform a retrospective analysis of the culling of contiguous premises as performed in 2001 and a simulation study of the effects of this policy on reducing the number of farms affected by disease. Our simulation results support previous studies and show that a national policy of contiguous premises (CPs) culling leads to fewer farms losing livestock. The optimal national policy for controlling the 2001 epidemic is found to be the targeting of all contiguous premises, whereas for localized outbreaks in high animal density regions, more extensive fixed radius ring culling is optimal. Analysis of the 2001 data suggests that the lowest-risk CPs were generally prioritized for culling, however, even in this case, the policy is predicted to be effective. A sensitivity analysis and the development of a spatially heterogeneous policy show that the optimal culling level depends upon the basic reproductive ratio of the infection and the width of the dispersal kernel. These analyses highlight an important and probably quite general result: optimal control is highly dependent upon the distance over which the pathogen can be transmitted, the transmission rate of infection and local demography where the disease is introduced.     

A Survey of Chinese Citizens’ Perceptions on Farm Animal Welfare

Farm animal welfare has been gradually recognized as an important issue in most parts of the world. In China, domestic animals were traditionally raised in backyard and treated as an important component of family wealth. Industrialization of animal production brings forth the farm animal welfare concerns recently in China, yet the modern concept of animal welfare has not been publicized and a comprehensive recognition on how consumers and farmers perceive animal welfare is lacking. Therefore, we conducted a survey on public opinions toward farm animal welfare in China, based on pigs (including sows, piglets, and fattening pigs), domestic fowls (including layers and broilers) and their products. From 6,006 effective questionnaires approximately two thirds of the respondents had never heard of ‘animal welfare’; 72.9% of the respondents claimed that, for the sake of animal derived food safety, human beings should improve the rearing conditions for pigs and domestic fowls; 65.8% of the respondents totally or partly agreed on establishing laws to improve animal welfare; more than half of the respondents were willing, or to some extent willing, to pay more for high-welfare animal products, whereas 45.5% of the respondents were not willing or reluctant to pay more. In summary, farm animal welfare is still in its early stage of development and more efforts are needed to improve the public conception to animal welfare in the process of establishing farm animal welfare standards and legislations in China.     

Efficacy of commercial vaccines for protecting guinea pigs against Bordetella bronchiseptica pneumonia

Autogenous bacterins are recommended to protect guinea pigs (Cavia porcellus) against pneumonia due to Bordetella bronchiseptica. Bordetella vaccines are available commercially for several other animal species. The substantial antigenic cross-reactivity among Bordetella isolates from various animal species suggests that immunity resulting from use of these vaccines might protect guinea pigs. Groups of ten individually housed Hartley guinea pigs from a colony free of Bordetella were vaccinated with one of two commercial porcine B. bronchiseptica vaccines, a human DPT vaccine (which includes a Bordetella pertussis component), or an autogenous B. bronchiseptica bacterin. Twenty-one days following vaccination, the animals were challenged with an intranasal dose of 10(6) virulent B. bronchiseptica cells. The animals were euthanized and necropsied 15 days after challenge. The nares, nasopharynx, distal trachea and lungs were cultured. All nonvaccinated control animals developed acute signs of pneumonia, while none of the vaccinated animals developed clinical signs of disease or gross lesions. The frequency of B. bronchiseptica isolation from the lungs of animals in each vaccine group was reduced. However, approximately 70% of all animals in each vaccine group harbored B. bronchiseptica in the trachea, and almost all harbored B bronchiseptica in the nares and nasopharynx. The porcine vaccines appeared to afford protection against acute pulmonary disease in the guinea pig.     

The impact of local heterogeneity on alternative control strategies for foot-and-mouth disease

The 2001 epidemic of foot-and-mouth disease (FMD) in the UK resulted in the death of nearly 10 million livestock at a cost that was estimated to be up to 8 billion pounds. Owing to the controversy surrounding the epidemic, the question of whether or not alternative policies would have resulted in significantly better control of the epidemic remains of great interest. A hexagonal lattice simulation of FMD in Cumbria is used to address the central question of whether or not better use could have been made of expert knowledge of FMD transmission to target pre-emptive culling, by assuming that the premises at greatest risk of becoming infected can be targeted for culling. The 2000 UK census and the epidemiological database collected during the epidemic are used to describe key characteristics of disease transmission, and the model is fit to the epidemic time-series. Under the assumptions of the model, the parameters that best fit the epidemic in Cumbria indicate that a policy based on expert knowledge would have exacerbated the epidemic compared with the policy as implemented. However, targeting more distant, high-risk farms could be more valuable under different epidemic conditions, notably, if risk factors of sufficient magnitude could be identified to aid in prioritizing vaccination or culling of farms at high risk of becoming infected.     

Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms

Massive numbers of palm civets were culled to remove sources for the reemergence of severe acute respiratory syndrome (SARS) in Guangdong Province, China, in January 2004, following SARS coronavirus detection in market animals. The virus was identified in all 91 palm civets and 15 raccoon dogs of animal market origin sampled prior to culling, but not in 1,107 palm civets later sampled at 25 farms, spread over 12 provinces, which were claimed to be the source of traded animals. Twenty-seven novel signature variation residues (SNVs) were identified on the spike gene and were analyzed for their phylogenetic relationships, based on 17 sequences obtained from animals in our study and from other published studies. Analysis indicated that the virus in palm civets at the live-animal market had evolved to infect humans. The evolutionary starting point was a prototype group consisting of three viral sequences of animal origin. Initially, seven SNV sites caused six amino acid changes, at positions 147, 228, 240, 479, 821, and 1080 of the spike protein, to generate low-pathogenicity viruses. One of these was linked to the first SARS patient in the 2003-2004 period. A further 14 SNVs caused 11 amino acid residue changes, at positions 360, 462, 472, 480, 487, 609, 613, 665, 743, 765, and 1163. The resulting high-pathogenicity groups were responsible for infections during the so-called early-phase epidemic of 2003. Finally, the remaining six SNVs caused four amino acid changes, at positions 227, 244, 344, and 778, which resulted in the group of viruses responsible for the global epidemic.     

Animal abuse in Massachusetts: a summary of case reports at the MSPCA and attitudes of Massachusetts veterinarians

This article reports information abstracted from 200 randomly sampled animal abuse complaints that the Massachusetts Society for the Prevention of Cruelty to Animals received in 1996, along with the results of 1 10 surveys that Massachusetts veterinarians completed concerning their experience with and attitudes and perceptions of animal mistreatment. In 1996, there were a total of 4,942 complaints of animal mistreatment, or 2.2 complaints per 1,000 households in Massachusetts. The majority of sampled complaints involved dogs (69.5%), cats (21.5%), or both. Almost all complaints involved husbandry-related neglect (62.0%), medical neglect (26.0%), or both. A violation of the law was observed by the investigating officer in 75 (37.5%) cases. The majority (78.9%) of veterinarians reported having observed at least 1 instance of animal abuse in their patients, although few encountered more than 5 cases (16.4%) during their years of practice. Almost all respondents (93.6%) agreed that veterinarians have an ethical responsibility to report suspicions of abuse, but a smaller number (44.5%) believed that this responsibility should be mandated.     

Quantification of the effect of control strategies on classical swine fever epidemics

Emergency vaccination during an epidemic of classical swine fever virus (CSFV) has become a serious option because of the ethical problems of strategies with massive culling and the availability of a marker vaccine that reduces virus transmission. Here we present a model of between-herd CSFV transmission, which quantifies the effect of control strategies with and without vaccination. We estimate the model parameters from data of the Dutch CSFV epidemic of 1997/1998. With the model, a set of control strategies is compared, consisting of five control measures in several combinations. Consequently, the following general requirements of successful strategies can be formulated. First, to achieve extinction of a CSFV epidemic, transmission through transport should be prevented and the indirect virus transmission, i.e. all transmission not through animal contacts, should at least be halved, either by vaccination or by culling of the susceptible pig population. Second, to minimize the size and duration of an epidemic, the extinction requirements should be met quickly and indirect virus transmission should be reduced by far more than a half. Although the origin of the model parameters let the requirements in fact be only applicable for the south-eastern part of the Netherlands, it is argued that epidemics in other areas will not need stricter control strategies.     

Acid glycohydrolase in Chinese hamster with spontaneous diabetes II. N-acetyl-beta-D-hexosaminidase in plasma and tissues

Excessively high activity of N-acetyl-beta-D-hexosaminidase (2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxy-glucohydrolase, EC 3.2.1.30) was found in the plasma of hereditary diabetic XA line animals, which however showed similar activity of this enzyme in both 12 00 X g supernatant and precipitate fractions of kidney homogenates as the nondiabetic M line animals. 0.1% Triton X-100 extracts of kidney, spleen, hind leg muscle, cheek pouch and spinal cord of XA and M line animals also showed similar activities of this enzyme whereas the XA animal liver extracts showed significantly higher activity than the M extracts. On a Sepharose CL-6B column, plasma N-acetyl-beta-D-hexosaminidase was eluted as two major peaks at 0 and 0.05 M NaCl (isozyme B1 and B2). Both isozymes showed pH optima between 3.5 and 4.0 and the same Michaelis constants for p-nitrophenyl-N-acetyl-beta-D-glucosaminide at pH 4.5, i.e. 0.18 mM. Isozymes from XA and M animals showed identical properties. N-acetyl-beta-D-hexosaminidase in the liver extracts was separated into 3 isozymes, A, B1 and B2, by successive column chromatography runs on Sepharose 6B and DEAE-Sepharose CL-6B. At 49 degrees C, isozyme B1 showed thermostability whereas B2 and A lost 20% and 76% of their activities after 30 min incubation, pH optima for A, B1 and B2 were 4.0--4.5, 3.5 and 3.5--4.0 respectively. The Km values for p-nitrophenyl-N-acetyl-beta-D-glucosaminide were 0.48 mM for A and 0.19 for B1 and B2. The XA animal liver extracts showed higher activities in all three isozymes than the M animal livers. Identical results, however, were obtained for liver isozymes from M and XA animals with regard to thermostability, pH vs. activity, elution profile on ion exchange column and affinity to p-nitrophenyl-N-acetyl-beta-D-glucosaminide.     

A self-assessment survey of the Institutional Animal Care and Use Committee, Part 1: animal welfare and protocol compliance

Nearly half of all external grants from the US National Institutes of Health require approval by the recipient organization's Institutional Animal Care and Use Committee (IACUC) before the funds can be used for research with animals. Given that large sums of money are spent annually on research involving animals, studies evaluating the strengths, weaknesses and overall effectiveness of IACUCs and similar animal welfare committees are needed. The authors designed and carried out a self-assessment survey on IACUC function and effectiveness. They found that 98% of all respondents believed that their IACUCs advanced animal welfare, but in many instances, veterinarians' responses to individual survey items were significantly different from those of other IACUC members. Protocol compliance, protocol review training and better understanding among non-committee members of the need for regulatory oversight are some areas where improvements could be made. Less than 50% of respondents stated that literature searches to find alternatives to animal use or painful or distressful procedures were helpful.     

Biosecurity and the review and publication of dual-use research of concern

Dual-use research of concern (DURC) is scientific research with significant potential for generating information that could be used to harm national security, the public health, or the environment. Editors responsible for journal policies and publication decisions play a vital role in ensuring that effective safeguards exist to cope with the risks of publishing scientific research with dual-use implications. We conducted an online survey of 127 chief editors of life science journals in 27 countries to examine their attitudes toward and experience with the review and publication of dual-use research of concern. Very few editors (11) had experience with biosecurity review, and no editor in our study reported having ever refused a submission on biosecurity grounds. Most respondents (74.8%) agreed that editors have a responsibility to consider biosecurity risks during the review process, but little consensus existed among editors on how to handle specific issues in the review and publication of research with potential dual-use implications. More work is needed to establish consensus on standards for the review and publication of dual-use research of concern in life science journals.     

Animal-Related Activities and Appreciation of Animals Among Children and Adolescents

ABSTRACT

Five hundred and sixty-two children and adolescents, aged between nine and 15 years, from one urban and three rural areas in Southern Norway, completed a questionnaire in which they expressed their degree of preference for various animal species, participation in animal-related activities, and the presence of pets at home. The results showed that a majority of the respondents had an animal at home (71%), and participated in animal-related activities such as fishing (72%), feeding birds (74%), and reading about animals (66%). Participation in most animal-related activities decreased with increasing age. Pet owners liked farm and wild animals more than did respondents without pets. Positive associations were found between the liking of animal species and participation in animal-related activities. Gender differences were largest for horseback riding (girls most) and for fishing and hunting (boys most). Those who reported allergic reactions to animals, or had been injured by an animal, liked animals as much as, or more than, did the other respondents.     

Corynebacterium Pseudotuberculosis Infection in Goats IV.

Adult animals from 2 herds were examined clinically and serologically, 5 (Herd A) and 4 (Herd B) times during the same period of 3% years. Serum samples were examined for antibodies against Gorynebac-terium pseudotuberculosis using the bacterial agglutination test (BAT) and the hemolysis inhibition test (HIT). The results of the first examination showed that no animal in Herd A was seropositive, while in Herd B 1 animal showed a high positive titre in BAT. The prevalence of animals with superficial swellings was then 2 % in Herd A and 4 % in Herd B. In both herds, the prevalence of animals with superficial swellings and seropositive reactions increased during the following 1–2 yeairs. About 30 % of animals had superficial lesions and close to 100 % were seropositive. The proportion, of animals with superficial swellings and seropositive reactions was almost constant on subsequent examinations. In some of the animals, superficial swellings were found during 2 or more of the examinations, a few animals having such lesions at the same site on both or all occasions. Animals in Herd A became infected through grazing together with goats from infected herds. Caseous lymphadenitis was introduced into Herd B by animals obtained from infected herds.     

Insights into European Drug Shortages: A Survey of Hospital Pharmacists

Drug shortages are a complex and global phenomenon. When a drug cannot be delivered at the moment of patient demand, every stakeholder in the health care system is affected. The aim of this study was to investigate the characteristics, clinical impact, financial impact and management of drug shortages in European hospital pharmacies and identify opportunities for prevention and mitigation of drug shortages in Europe. An online survey was designed based on a review of the literature and interviews and was sent to subscribers of Hospital Pharmacy Europe between June and September 2013. Forty-five percent of respondents (n = 161) indicated that life sustaining or life preserving drugs such as oncology drugs were affected by drug shortages. More than 30% of respondents indicated that drug shortages in Europe were always or often associated with increased costs for hospitals, increased personnel costs and more expensive alternative drugs (n = 161). On the question when information about a drug shortage was obtained, 42% of respondents answered that information from the pharmaceutical company was obtained at the time of no delivery, 50% indicated that information from the wholesaler was obtained at the time of no delivery, while 40% of respondents indicated that information was never or rarely received from the government (n = 161). Fifty seven percent of respondents strongly agreed that an obligation to the producer to notify further shortages could help to solve the problem (n = 161). These results showed that pharmaceutical companies and wholesalers are already involved in the management of drug shortages, while a role is still reserved for the government. Mandatory notification in advance and centralized information can help to reduce workload for hospital pharmacists, will allow early anticipation of drug shortages and will facilitate mitigation of the clinical impact on patients.     

Associations between the breeding values of Holstein-Friesian bulls and longevity and culling reasons of their daughters

Taking into account functional traits in the breeding practice should lead to a longer productive life of cows. However, despite the increased contribution of these traits in bull selection indices, their daughters are frequently culled as early as the 2nd or 3rd lactation. The problem is whether and to what extent the genetic potential of animals is realized in the production practice. Therefore, the purpose of this study was to determine the associations between the breeding value (BV) of bulls and their daughters for cow longevity and culling reasons in the Holstein-Friesian cattle population in Poland. Data for 532 062 cows culled in 2012, 2015, and 2018 were analyzed. A majority of 5 045 cow sires originated from Poland, Germany, France, the Netherlands, and the United States. The highest variation in the contribution of culling reasons was for the cows culled at the age of 2–4 years. The contribution of the culling reasons, analyzed in relation to the cow culling age, remained similar and the only exception was culling because of old age, for which a significant increase was observed only for the culling age of at least 9 years (13.8%), which was reached by only 7.3% of the cows. The sires were characterized by generally high BV for conformation and reproductive traits. However, they had, at most, the average genetic potential for functional longevity. There were a number of beneficial associations found between the BV of bulls and the distribution of culling reasons in their daughters. For example, it concerns relations between the somatic cell score in milk and culling due to udder diseases and low milk yield, between the interval from calving to first insemination and low milk yield, between the protein yield and old age, or between the BV for certain conformation traits (size, udder) and cow culling due to age. In these cases, as the BV increased for a given trait, the contribution of the corresponding cow culling reason tended to decrease. Our study showed that it seems reasonable to consider Holstein-Friesian cows aged at least 9 years at culling to be long-living animals. This is primarily evidenced by the rapid increase in the culling due to old age in relation to younger cows. Nowadays the above age limit can be suggested as a criterion of longevity for Holstein-Friesian cows but the criterion should be updated to the relation genotype-environment-economy that tends to change over time.     

Human–Animal Bonds Between Zoo Professionals and the Animals in Their Care

Some human‐animal relationships can be so positive that they confer emotional well‐being to both partners and can thus be viewed as bonds. In this study, 130 delegates at zoo research and training events completed questionnaires in which they were asked about their professional work in the zoo and whether they believed they had established bonds with any animals. They were also asked to indicate agreement or disagreement with several statements about human‐animal bonds. Results showed that many zoo professionals consider that they have established bonds with some of their animals; 103 respondents believed that they had a bond with at least one animal, and 78 of these identified that the bond was with a zoo animal. The most frequent bonds reported were with primates (n = 24) and carnivores (n = 28). Perceived benefits of these bonds to the respondents included both operational (animal easier to handle, easier to administer treatments to) and affective (sense of well‐being, enjoyment at being with the animal). Identifying benefits to the animals was more difficult. Most respondents identified similar benefits for their animals as for themselves, i.e. operational (animal responded more calmly, appeared less stressed) and affective (animal appeared to enjoy contact with respondent, seemed more content). This suggests that bonding between zoo professionals and their animals could have profound consequences for the management and welfare of the animals, not to mention the job satisfaction of the people involved. Zoo Biol 31:13;–26, 2012. © 2010 Wiley Periodicals, Inc.