Tetrachloroplatinate(II) and hexachloroplatinate(IV) salts of N,N,N′,N′-tetramethylethylenediammonium: significant differences in the conformation of the cation, as shown by infrared and x-ray diffraction data

The structures of (H₂tmen)[PtCl₄], (1), (H₂tmen = N,N,N′,N′-tetramethylethylenediammonium), [triclinic, P ; A = 7.344(3), B = 8.345(3), C = 6.216(2) Å, α = 84.53(3), β = 109.22(3), γ = 69.43(3)°, Z = 1] and (H₂tmen)[PtCl₆], (2), [monoclinic, P2₁/a; A = 14.409(4), B = 12.736(7), C = 8.601(3) Å, β = 99.58(3)°, Z = 4] were determined from diffractometric data by Patterson and Fourier methods and refined by full-matrix least-squares to R = 0.027 and 0.039 for (1) and (2) respectively. In both cases the anions and cations are joined in polymeric chains through hydrogen bonds involving the protonated nitrogens and the co-ordinated chlorine atoms. The square-planar [PtCl₄]²⁻ and octahedral [PtCl₆]²⁻ anions are centrosymmetric; the H₂tmen²⁺ cations are centrosymmetric in (1) with a N-C-C-N dihedral angle of exactly 180°, while in (2) the dihedral angle is 166°. The different symmetry of the organic moieties/C_i and C₁ in (1) and (2) respectively] results in a different i.r. spectrum which is more complex the lower the symmetry; moreover the spectrum of a KBr pellet of (2) changes with time, finally resembling that of (1) and of the (H₂tmen)Cl₂ salt.     

Crystal structure of [chloro(diethyldithiocarbamato)butyl phenyl]tin(IV)

The crystal structure of the title compound, SnCl(C₆H₅)(C₄H₉)[S₂CN(C₂H₅)₂], was determined and refined to an R factor of 3.2% for 4876 reflections. The molecule contains five-coordinate tin in a distorted trigonal bipyramidal arrangement with the tin atom lying 0.20 Å below the equatorial plane formed by one of the sulphur atoms, S(1), and the donor carbons of the butyl and phenyl groups. The chlorine and the other sulphur atom, S(2), occupy axial sites, making a S(2)SnCl angle of 156.85(1)°. The SnS(2) bond is markedly elongated (2.764(1) Å) compared to the SnCl bond (2.449(1) Å) and the SnS(1) bond (2.454(1) Å). The structure resembles those of analogues such as (C₆H₅)₂Sn(glygly) in having both hydrocarbon ligands located in the equatorial plane. Crystal data: space group P$\text{1}$: a = 8.291(2) Å, b = 14.726(3) Å, c = 9.509(2) Å, α = 96.24(2)°, β = 107.02(3)°, γ = 116.70(2)°, Z = 2, R = 3.2% for 4876 independent reflections.     

Syntheses and single crystal structures of chiral tetrahedral clusters containing osmium

New chiral tetrahedral clusters (μ₃-S)OsCoMo(CO)₈C₅H₄C(O)R(R = H 2, CH₃ 3, C₆H₄C(O)OCH₃ 4) were synthesized by the reaction of the precursor (μ₃-S)OsCo₂(CO)₉ 1 with the functionally substituted metal exchange reagents [Mo(CO)₃(η⁵-C₅H₄)C(O)R]⁻ (R = H, CH₃, C₆H₄C(O)OCH₃). Then clusters 2, 3 and 4 were treated with 2,4-dinitrophenylhydrazine to obtain clusters (μ₃-S)OsCoMo(CO)₈C₅H₄CNNHC₆H₃(NO₂)₂R (R = H 5, CH₃ 6, C₆H₄C(O)OCH₃ 7), respectively. All the clusters were characterized by Element Analysis, IR and ¹H NMR. The structures of clusters 3 and 4 were established by X-ray single crystal diffraction. Interestingly, carbonyl group on the cyclopentadienyl ligand and cyclopentadienyl ring are not in the same plane, in cluster 3, torsion angle C₂₇-C₂₈-C₂₉-O₁₈ is −176.1(9), but in cluster 4, torsion angle C₁₂-C₁₃-C₁₄-O₉ is 167.5(17), which shows that carbonyl function group on the cyclopentadienyl ligand offsets the cyclopentadienyl ring more markedly than that in cluster 3. It showed that both conjugated effects and space hinder of phenyl ring in the cluster 4 are important factors to decide atoms positioning in three-dimensional structure of the clusters.     

Effect of ethylene and 1-methylcyclopropene on chlorophyll catabolism of broccoli florets

Branchlets of broccoli (Brassica oleracea L.) were used to examine ethylene-stimulated chlorophyll catabolism. Branchlets treated with: 1) air (CK); 2) 1 µL·L^–1 1-methylcyclopropene (1-MCP) for 14 hr at 20 °C; 3) 1000 µL·L^–1 ethylene (C₂H₄) for 5 hr at 20 °C; or 4) 1-MCP then C₂H₄, were stored in the dark at 20 °C for up to 3 d. Chlorophyll (Chl) content and branchlet hue angle decreased during the storage period and 1-MCP treatment delayed this change. Chl degradation in broccoli was accelerated by exposure to C₂H₄, especially for Chl a. Prior treatment with 1-MCP prevented degreening stimulated by C₂H₄. Lipoxygenase activity was not altered by any of the treatments, however, 1-MCP with or without ethylene resulted in reduced activity of chlorophyllase (Chlase) and peroxidase (POD). Exposure to C₂H₄ stimulated Chlase activity and extended the duration of high POD activity. Treatment with 1-MCP followed by C₂H₄ resulted in reduced POD activity and delayed the increase in Chlase activity. The results suggest chlorophyll in broccoli can be degraded via the POD – hydrogen peroxide system. Exposure to C₂H₄ enhances activity of Chlase and extends the duration of high POD activity, and these responses may accelerate degreening. Treatment with 1-MCP delays yellowing of broccoli, an effect that may be due to the 1-MCP-induced reduction in POD and Chlase activities.     

Does Ethylene Play a Role in the Release of Lateral Buds (Tillers) from Apical Dominance in Oats?

The growth of lateral buds (tillers), which are undergoing release from apical dominance, was measured in upright and gravistimulated intact Avena sativa L. cv. `Victory' (oat) shoots as well as in isolated Avena stem segments treated with kinetin and sucrose. During release, the tiller bud initially shows a slow rate of elongation accompanied by swelling. It is followed by a more rapid rate of elongation. Ethylene (C₂H₄) production in shoot segments containing a tiller bud was found to occur at the onset of tiller swelling during gravistimulation as well as during inflorescence emergence. Exogenous application of indoleacetic acid or C₂H₄ inhibits kinetin-induced tiller bud swelling and elongation. However, stem segments pulsed for 24 hours in C₂H₄ or the C₂H₄ biosynthesis precursor, 1-amino-cyclopropane-1-carboxylic acid (ACC) and then transferred to kinetin and sucrose, showed a significant increase in swelling elongation as compared with segments maintained under the same conditions but without C₂H₄ or ACC in the pulse. Segments pulsed for 24 hours with kinetin and sucrose plus the ACC biosynthesis inhibitor, aminoethoxyvinylglycine, or the C₂H₄ action inhibitor, CO₂, then transferred to kinetin and sucrose medium, showed inhibition of tiller swelling during the pulse and of subsequent elongation. These results indicate that C₂H₄ plays a role in promoting tiller swelling during the onset of tiller release from apical dominance and may act as a modulator hormone in promoting tiller elongation in the presence of cytokinin.     

Synthesis and structure of an unusual di-rhodium diarylbutadiyne π-complex featuring a μ-(1,2-η2):(3,4-η2)-p-CF3C6H4–CC–CC–C6H4-p-CF3 moiety

Reaction of the salt [Rh(PMe₃)₄]Cl (1) with p-F₃C–C₆H₄–CC–CC–C₆H₄-p-CF₃ (2) in THF gives a mixture of two related neutral π-bound diyne complexes of [Rh(PMe₃)₃Cl], each having two distinct CF₃ resonances of equal intensity in the in situ ¹⁹F{¹H} NMR spectrum. The ratio of the two products can be varied by varying the stoichiometry of the reagents. On the basis of the spectroscopic data and literature precedent, we propose Rh(PMe₃)₃(Cl)((1,2-η²)-p-F₃C–C₆H₄–CC–CC–C₆H₄-p-CF₃) (3a) and [Rh(PMe₃)₃(Cl)]₂(μ-(1,2-η²):(1,2-η²)-p-F₃C–C₆H₄–CC–CC–C₆H₄-p-CF₃) (3b) as the most likely structures of the species in solution. However, upon standing overnight, single crystals of the unusual, dinuclear complex [Rh(PMe₃)₃(Cl)]₂(μ-(1,2-η²):(3,4-η²)-p-F₃C–C₆H₄–CC–CC–C₆H₄-p-CF₃) (4), an isomer of 3b, form reproducibly and in good yield as two different solvates from THF/C₆D₆ solution. The centrosymmetric structure of 4, obtained from single-crystal X-ray diffraction data, displays a transoid orientation of the bridging diarylbutadiyne ligand.     

Effect of pO(2) on Growth and Nodule Functioning of Symbiotic Cowpea (Vigna unguiculata L. Walp.)

Nodulated cowpea (Vigna unguiculata L. Walp. cv Vita 3:Bradyrhizobium CB 756) plants were cultured with their whole root system or crown root nodulation zone maintained for periods from 5 to 69 days after planting in atmospheres containing a range of pO₂ (1-80%, v/v) while the rest of the plant grew in normal air. Growth (dry matter yield) and N₂ fixation were largely unaffected by pO₂ from 10 to 40%. Decrease in fixation at pO₂ below 5% was due to lower nodulation and nodule mass and, at pO₂ above 60%, to a fall in specific N₂-fixing activity of nodules. Root:shoot ratios were significantly lower at pO₂ below 2.5%. The effect of pO₂ on nitrogenase activity (acetylene reduction), both of whole nodulated root systems and crown root nodulation zones, varied with plant age but was generally lower at supra- and subambient extremes of O₂. H₂ evolution showed a sharp optimum at 20% O₂ but was at most 4% of total nitrogenase activity. The ratio of CO₂ evolved to substrate (C₂H₂+H⁺) reduced by crown root nodulation zones was constant (6 moles CO₂ per mole substrate reduced) from 2.5 to 60% O₂ but at levels below 2.5 and above 80% O₂ reached values between 20 and 30 moles CO₂ per mole substrate reduced. Effects of long-term growth with nonambient pO₂ on adaptation and efficiency of functioning of nodules are discussed.     

Synthesis of new mer,trans-rhodium(III) hydrido-bis(acetylide) complexes: Structure of mer,trans-[(PMe3)3Rh(CC–C6H4-4-NMe2)2H]

Terminal alkynes (R–CC–H, R = 1-naphthyl, 9-anthryl, 4-Me₂N–C₆H₄–, or the longer analogue, 4-(4-Me₂N–C₆H₄–CC–)–C₆H₄–) react with [Rh(PMe₃)₄Me] at ambient temperature, with loss of methane and one PMe₃ ligand, to form the corresponding mer,trans-[(PMe₃)₃Rh(CCR)₂H] compounds in excellent yield. In this preliminary study, the synthesis and spectroscopic characterization of the four new compounds are reported, along with the single-crystal structure of the R = 4-Me₂N–C₆H₄ derivative.     

Novel oxorhenium(V) ‘3+1’ mixed ligand complexes with 3-thiapentane-1,5-dithiolate and functional mercaptobenzoyl amino acid ethyl ester

Oxorhenium(V) complexes with ‘3+1’ mixed ligands, [ReO(SSS)L], where SSS is η³-(SCH₂CH₂SCH₂CH₂S), L = η¹-(C₆H₄COOH-4-S), η¹-(C₆H₄CONHCH₂COOEt-4-S), η¹-(C₆H₄CONHCH(CH₃)COOEt-4-S), and η¹-(C₆H₄CONHCH(CH₂Ph)COOEt-4-S), have been synthesized. These L ligands and [ReO(SSS)L] complexes were characterized by IR, ¹H NMR, ¹³C NMR, and MAS spectrometers. Molecular structure of [ReO(SSS){η¹-(C₆H₄COOH-4-S)}] complex was determined to be a distorted square pyramidal by single crystal X-ray analytical method.     

Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life

This study compares the local conformational dynamics and physical stability of an IgG1 mAb (mAb-A) with its corresponding YTE (M255Y/S257T/T259E) mutant (mAb-E), which was engineered for extended half-life in vivo. Structural dynamics was measured using hydrogen/deuterium (H/D) exchange mass spectrometry while protein stability was measured with differential scanning calorimetry (DSC) and size exclusion chromatography (SEC). The YTE mutation induced differences in H/D exchange kinetics at both pH 6.0 and 7.4. Segments covering the YTE mutation sites and the FcRn binding epitopes showed either subtle or no observable differences in local flexibility. Surprisingly, several adjacent segments in the C_H2 and distant segments in the V_H, C_H1, and V_L domains had significantly increased flexibility in the YTE mutant. Most notable among the observed differences is increased flexibility of the 244–254 segment of the C_H2 domain, where increased flexibility has been shown previously to correlate with decreased conformational stability and increased aggregation propensity in other IgG1 mAbs (e.g., presence of destabilizing additives as well as upon de-glycosylation or methionine oxidation). DSC analysis showed decreases in both thermal onset (T_onset) and unfolding (T_m1) temperatures of 7°C and 6.7°C, respectively, for the C_H2 domain of the YTE mutant. In addition, mAb-E aggregated faster than mAb-A under accelerated stability conditions as measured by SEC analysis. Hence, the relatively lower physical stability of the YTE mutant correlates with increased local flexibility of the 244–254 segment, providing a site-directed mutant example that this segment of the C_H2 domain is an aggregation hot spot in IgG1 mAbs.     

Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life

This study compares the local conformational dynamics and physical stability of an IgG1 mAb (mAb-A) with its corresponding YTE (M255Y/S257T/T259E) mutant (mAb-E), which was engineered for extended half-life in vivo. Structural dynamics was measured using hydrogen/deuterium (H/D) exchange mass spectrometry while protein stability was measured with differential scanning calorimetry (DSC) and size exclusion chromatography (SEC). The YTE mutation induced differences in H/D exchange kinetics at both pH 6.0 and 7.4. Segments covering the YTE mutation sites and the FcRn binding epitopes showed either subtle or no observable differences in local flexibility. Surprisingly, several adjacent segments in the C_H2 and distant segments in the V_H, C_H1, and V_L domains had significantly increased flexibility in the YTE mutant. Most notable among the observed differences is increased flexibility of the 244–254 segment of the C_H2 domain, where increased flexibility has been shown previously to correlate with decreased conformational stability and increased aggregation propensity in other IgG1 mAbs (e.g., presence of destabilizing additives as well as upon de-glycosylation or methionine oxidation). DSC analysis showed decreases in both thermal onset (T_onset) and unfolding (T_m1) temperatures of 7°C and 6.7°C, respectively, for the C_H2 domain of the YTE mutant. In addition, mAb-E aggregated faster than mAb-A under accelerated stability conditions as measured by SEC analysis. Hence, the relatively lower physical stability of the YTE mutant correlates with increased local flexibility of the 244–254 segment, providing a site-directed mutant example that this segment of the C_H2 domain is an aggregation hot spot in IgG1 mAbs.     

Hydrogen peroxide sensor based on Prussian blue electrodeposited on (3-mercaptopropyl)-trimethoxysilane polymer-modified gold electrode

A hydrogen peroxide (H₂O₂) sensor was developed by electrodepositing Prussian blue (PB) on a gold electrode modified with (3-mercaptopropyl)-trimethoxysilane (MPS) polymer. The characterization of the self-assembled electrode was investigated by cyclic voltammetry and electrochemical impedance spectroscopy. The results of electrochemical experiments showed that such constructed sensor had a favorable catalytic ability to reduce H₂O₂. The MPS film on the modified gold electrode greatly enhanced the pH-adaptive range of PB. Large surface-to-volume ratio property of double-layer 2d-network MPS-modified PB electrode enabled stable and highly sensitive performance of the non-enzymatic H₂O₂ sensor. The linear range of H₂O₂ determined is from 2.0 × 10⁻⁶ to 2.0 × 10⁻⁴ mol L⁻¹ with a correlation coefficient of 0.9991 and a detection limit for H₂O₂ of 1.8 × 10⁻⁶ mol L⁻¹. The influences of the potentially interfering substances on the determination of H₂O₂ were investigated. This modified electrode exhibits a good selectivity and high sensitivity with satisfactory results.     

Organogold(I) complexes of a C2-symmetric diacetylide ligand derived from 1,1′-bi-2-naphthol

Alkynylgold(I) complexes incorporating a chiral binaphthyl group have been prepared. Bis(alkyne) reagents [rac-1,1′-C₂₀H₁₂-2,2′-(OCH₂CCH)₂] (1) and [rac-1,1′-C₂₀H₁₂-2,2′-(OC(O)CH₂CCH)₂] (2), react with [AuCl(SMe₂)] and base to give insoluble oligomeric alkynylgold(I) complexes [rac-1,1′-C₂₀H₁₂-2,2′-(OCH₂CCAu)₂]_n (3) and [rac-1,1′-C₂₀H₁₂-2,2′-(OC(O)CH₂CCAu)₂]_n (4), which react with phosphine or diphosphine ligands to give soluble complexes [rac-1,1′-C₂₀H₁₂-2,2′-(OCH₂CCAuPR₃)₂] (5), R = Ph or Cy, [rac-1,1′-C₂₀H₁₂-2,2′-(OCH₂CCAu)₂(Ph₂P(CH₂)_nPPh₂)] (6), or [rac-1,1′-C₂₀H₁₂-2,2′-(OC(O)CH₂CCAu)₂(Ph₂P(CH₂)_nPPh₂)] (7), with n = 3–5. Several of the complexes 6 and 7 are shown to exist as mixtures of isomeric forms in solution.     

Ethylene and carbon dioxide production by developing strawberries show a correlative pattern that is indicative of ripening climacteric fruit

Laser photoacoustic spectroscopy continuously quantified the ethylene (C₂H₄) produced by strawberry flowers and fruits developing in planta. C₂H₄ was first detected as flower buds opened and exhibited diurnal oscillations (to approximately 200 pl flower^?1 h^?1) before petal abscission. Exogenous application of silver thiosulphate (STS) to detached flowers inhibited petal abscission and flower senescence. In fruit, C₂H₄ production was maintained at a ‘low level’ (10–60 pl fruit^?1 h^?1) until fruit expanded when levels increased in a diurnal pattern (to 200 pl fruit^?1 h^?1). After expansion, C₂H₄ production declined to a low level until fruit attained the red‐ripe stage for at least 24 h. After this time, C₂H₄ levels increased linearly (no diurnal fluctuation) to approximately 1 nL fruit^?1 h^?1. Twenty‐four hours after the re‐initiation of C₂H₄ production by red fruit, CO₂ levels increased approximately three‐fold, indicative of a respiratory climacteric. STS applied to fruits developing in planta and dissected fruit parts ex situ established that C₂H₄ production is regulated by negative feedback until fruits had expanded. The C₂H₄ produced by red‐ripe fruit was regulated by positive feedback. Anti‐1‐amino‐cyclopropane‐1‐carboxylic acid oxidase IgG localization identified immunoreactive antigens of 40 and 30 kDa (M_r) within the fruit achenes of expanding and red‐ripe fruit. Analysis of dissected fruit showed that seed C₂H₄ accounts for 50% the C₂H₄ that is detectable from ripe fruit.     

Dynamics of Cytokine/Chemokine Responses in Intestinal CD4+ and CD8+ T Cells during Acute Simian Immunodeficiency Virus Infection

Loss of intestinal CD4⁺ T cells was associated with decreased production of several T-helper 1 (T_H1) and T_H2 cytokines and increased production of interleukin 17 (IL-17), gamma interferon (IFN-γ), CCL4, and granulocyte-macrophage colony-stimulating factor (GM-CSF) by CD8⁺ T cells 21 days after simian immunodeficiency virus (SIV) infection in rhesus macaques. Shifting of mucosal T_H1 to T_H2 or T-cytotoxic 1 (T_C1) to T_C2 cytokine profiles was not evident. Additionally, both CD4⁺ and CD8⁺ T cells showed upregulation of macrophage migration inhibition factor (MIF) and basic fibroblast growth factor (FGF-basic) cytokines that have been linked to HIV disease progression.     

Interspecific patterns underlying variations in allometric relationship of sympatric Sterculiaceae species in a Bornean rainforest

We compared aboveground tree forms among closely related species in two genera of the Sterculiaceae (Scaphium and Heritiera) in a Bornean mixed dipterocarp forest. Two significant allometric patterns were detected: a negative correlation between the height at the onset of branching and the slope of the species-specific Cr (crown width)-D (stem diameter) allometric relationship for juveniles (D<10 cm), and a negative correlation between H _max (observed maximum height) and the Cr-D slope. The slope of the Cr-D allometric relationship of branched trees was significantly steeper than that of monoaxial (unbranched) trees in most species. These results suggest that the branching growth habit is better adapted than the monoaxial growth habit to crown expansion, and that the morphology of short species is better adapted to crown expansion than that of tall species. We did not detected significant correlations between the height at the onset of branching and the slope of the H (height)-D allometric relationship for juvenile trees, and between H _max and the H-D slope. In addition, the monoaxial and branched juvenile of most species did not differ significantly in the allometric slopes of the H-D relationship. Therefore, the study does not support the hypotheses that a monoaxial growth habit favors rapid height growth and that tall species have allometries better adapted to height growth.     

Fluidity of Liposome Membranes Doped with Organic Tin Compounds: ESR Study

The kinetics of change in the fluidity of liposome membranes, obtained in the process of sonication of Egg Yolk Lecithin (EYL), with the admixture of organic tin compounds, was investigated. Five compounds were selected for the research: three differed in the length of hydrocarbon chains, (CH₃)₄Sn, (C₂H₅)₄Sn, and (C₃H₇)₃SnCl, whereas two differed in the number of aromatic rings, (C₆H₅)₂SnCl₂ and (C₆H₅)₃SnCl. The concentration of the compounds in proportion to EYL was 2 mol-%. Electron Spin (paramagnetic) Resonance (ESR) was applied using two spin probes TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) and 16-DOXYL-stearic acid methyl ester (2-ethyl-2-(15-methoxy-15-oxopentadecyl)-4,4-dimethyl-3-oxazolidinyloxyl) localized at different sites within the membrane, to determine the spectroscopic parameters: partition (F) and rotation correlation time (τ), related to the membrane's fluidity. The ESR spectroscopic spectra of investigated samples were recorded from the moment of introducing the admixture to membranes for 180h. Analysing the obtained results, the following conclusions can be drawn: chain compounds slightly stiffened the membrane both on the inside (hydrophobic) layer and on the surface one, whereas ring compounds resulted in fluidization of the membrane—stronger in the case of the two-layer middle and weaker with reference to the surface layer.     

The hydrogenase-nitrogenase relationship in the blue-green algaAnabaena cylindrica

Nitrogen-fixingAnabaena cylindrica cells are found to evolve hydrogen in high quantities in the presence of CO plus C₂H₂. Studies with the inhibitors dichlorophenyldimethylurea (DCMU), disalicylidenepropanediamine (DSPD), dibromothymoquinone (DBMIB), undecylbenzimidazole (UDB) and chloro-carbonyl-cyanide-phenylhydrazone (CCCP) and also withAnabaena grown on nitrate- and ammonia-nitrogen show that the H₂-formation is due to the ATP-dependent H₃O⁺-reduction catalysed by nitrogenase. In control experiments CO plus C₂H₂ inhibited the activities of a cell-free hydrogenase fromClostridium pasteurianum. It is concluded that Anabaena has a hydrogenase whose natural function is to recycle the H₂ lost by the action of nitrogenase.Abbreviations Cl-CCP m-chloro-carbonyl-cyanide-phenylhydrazone - DSPD disalicylidenepropanediamine(1–3) - DBMIB dibromothymoquinone - DCMU N-(3,4-dichlorophenyl) NN-dimethyl-urea - UDB 2-undecyl-benzimidazole     

Preparation and properties of partially oxidized N-methylisoquinolinium bis(oxalato)platinate nanowires

Electrochemical oxidation of [C₁₀H₁₀N]₂[Pt(ox)₂] · H₂O (1) (C₁₀H₁₀N = N-methylisoquinolinium, ox = oxalate) leads to the synthesis of new partially oxidized platinum nanowires of formula [C₁₀H₁₀N]_1.6[Pt(ox)₂] · 3H₂O (2). The nanowires were characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Wires with diameters of less than 5 nm and lengths of over 1 μm were observed. Energy dispersive spectroscopy (EDS) and microanalysis confirmed the degree of partial oxidation of the nanowires. The bulk electrical properties including phase angle and real and imaginary impedance values were measured and a model of the electrical conduction circuit was proposed. The significance of this work is that the large N-methylisoquilolinium cation leads to nanostructures, possibly involving individual molecular wires which has not been previously observed in the bis(oxalato)platinate nanowire system.